MAFG.H12INVIVO.1.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFG.H12INVIVO.1.PSM.A
Gene (human)	MAFG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	15
Consensus	dhdYGCTGAYdhnnn
GC content	47.95%
Information content (bits; total / per base)	12.12 / 0.808
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9953

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.889	0.946	0.876	0.919	0.885	0.915	4.123	4.838	314.784	767.854
Mouse	2 (14)	0.989	0.991	0.979	0.981	0.984	0.986	5.848	5.921	699.81	867.149

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.987	0.979	0.937	0.93	0.801	0.814
Overall, 6 experiments	best	0.998	0.997	0.975	0.967	0.896	0.878
Methyl HT-SELEX, 2 experiments	median	0.972	0.958	0.918	0.902	0.807	0.804
Methyl HT-SELEX, 2 experiments	best	0.993	0.989	0.972	0.963	0.878	0.873
Non-Methyl HT-SELEX, 4 experiments	median	0.988	0.98	0.937	0.93	0.795	0.814
Non-Methyl HT-SELEX, 4 experiments	best	0.998	0.997	0.975	0.967	0.896	0.878

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	11.08	10.732	0.317	0.167

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.861	0.541	0.831	0.541
batch 2	0.66	0.416	0.688	0.491

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.2
HGNC	HGNC:6781
MGI	MGI:96911
EntrezGene (human)	GeneID:4097 (SSTAR profile)
EntrezGene (mouse)	GeneID:17134 (SSTAR profile)
UniProt ID (human)	MAFG_HUMAN
UniProt ID (mouse)	MAFG_MOUSE
UniProt AC (human)	O15525 (TFClass)
UniProt AC (mouse)	O54790 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 2 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	MAFG.H12INVIVO.1.PSM.A.pcm
PWM	MAFG.H12INVIVO.1.PSM.A.pwm
PFM	MAFG.H12INVIVO.1.PSM.A.pfm
Alignment	MAFG.H12INVIVO.1.PSM.A.words.tsv
Threshold to P-value map	MAFG.H12INVIVO.1.PSM.A.thr
Motif in other formats
JASPAR format	MAFG.H12INVIVO.1.PSM.A_jaspar_format.txt
MEME format	MAFG.H12INVIVO.1.PSM.A_meme_format.meme
Transfac format	MAFG.H12INVIVO.1.PSM.A_transfac_format.txt
Homer format	MAFG.H12INVIVO.1.PSM.A_homer_format_0.001.txt MAFG.H12INVIVO.1.PSM.A_homer_format_0.0005.txt MAFG.H12INVIVO.1.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	4207.25	1025.25	1155.25	3565.25
02	3723.75	1053.75	821.75	4353.75
03	2955.0	1298.0	1546.0	4154.0
04	346.0	2212.0	150.0	7245.0
05	67.0	124.0	9719.0	43.0
06	83.0	9802.0	32.0	36.0
07	10.0	132.0	68.0	9743.0
08	46.0	5.0	9746.0	156.0
09	9807.0	31.0	48.0	67.0
10	190.0	7163.0	1118.0	1482.0
11	1919.0	1119.0	2103.0	4812.0
12	2257.0	3847.0	1409.0	2440.0
13	3380.0	1515.0	2835.0	2223.0
14	2226.25	1607.25	3851.25	2268.25
15	1973.25	3926.25	2125.25	1928.25

PFM

	A	C	G	T
01	0.423	0.103	0.116	0.358
02	0.374	0.106	0.083	0.437
03	0.297	0.13	0.155	0.417
04	0.035	0.222	0.015	0.728
05	0.007	0.012	0.976	0.004
06	0.008	0.985	0.003	0.004
07	0.001	0.013	0.007	0.979
08	0.005	0.001	0.979	0.016
09	0.985	0.003	0.005	0.007
10	0.019	0.72	0.112	0.149
11	0.193	0.112	0.211	0.483
12	0.227	0.387	0.142	0.245
13	0.34	0.152	0.285	0.223
14	0.224	0.161	0.387	0.228
15	0.198	0.394	0.214	0.194

PWM

	A	C	G	T
01	0.525	-0.885	-0.766	0.359
02	0.403	-0.858	-1.106	0.559
03	0.172	-0.65	-0.475	0.512
04	-1.967	-0.118	-2.794	1.068
05	-3.582	-2.982	1.362	-4.007
06	-3.374	1.37	-4.285	-4.175
07	-5.311	-2.92	-3.567	1.364
08	-3.943	-5.832	1.365	-2.756
09	1.371	-4.315	-3.902	-3.582
10	-2.561	1.057	-0.799	-0.518
11	-0.26	-0.798	-0.168	0.659
12	-0.097	0.435	-0.568	-0.02
13	0.306	-0.496	0.13	-0.113
14	-0.111	-0.437	0.436	-0.092
15	-0.232	0.456	-0.158	-0.255

Standard thresholds

P-value	Threshold
0.001	3.74826
0.0005	4.89456
0.0001	7.41906