MAFG.H12INVITRO.1.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFG.H12INVITRO.1.PSM.A
Gene (human)	MAFG (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafg
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	15
Consensus	ndTGCTGAYdhddbn
GC content	50.69%
Information content (bits; total / per base)	12.139 / 0.809
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	2433

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.878	0.922	0.829	0.866	0.854	0.898	3.324	4.31	285.553	678.854
Mouse	2 (14)	0.98	0.982	0.957	0.961	0.971	0.973	5.124	5.197	669.926	838.013

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 6 experiments	median	0.987	0.978	0.941	0.934	0.809	0.821
Overall, 6 experiments	best	0.995	0.993	0.977	0.967	0.917	0.9
Methyl HT-SELEX, 2 experiments	median	0.964	0.946	0.91	0.891	0.807	0.8
Methyl HT-SELEX, 2 experiments	best	0.989	0.981	0.972	0.96	0.887	0.879
Non-Methyl HT-SELEX, 4 experiments	median	0.988	0.981	0.941	0.934	0.809	0.823
Non-Methyl HT-SELEX, 4 experiments	best	0.995	0.993	0.977	0.967	0.917	0.9

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	6.489	7.767	0.283	0.173

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.864	0.535	0.833	0.559
batch 2	0.657	0.419	0.669	0.444

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.2
HGNC	HGNC:6781
MGI	MGI:96911
EntrezGene (human)	GeneID:4097 (SSTAR profile)
EntrezGene (mouse)	GeneID:17134 (SSTAR profile)
UniProt ID (human)	MAFG_HUMAN
UniProt ID (mouse)	MAFG_MOUSE
UniProt AC (human)	O15525 (TFClass)
UniProt AC (mouse)	O54790 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 2 mouse
HT-SELEX	4
Methyl-HT-SELEX	2

PCM	MAFG.H12INVITRO.1.PSM.A.pcm
PWM	MAFG.H12INVITRO.1.PSM.A.pwm
PFM	MAFG.H12INVITRO.1.PSM.A.pfm
Alignment	MAFG.H12INVITRO.1.PSM.A.words.tsv
Threshold to P-value map	MAFG.H12INVITRO.1.PSM.A.thr
Motif in other formats
JASPAR format	MAFG.H12INVITRO.1.PSM.A_jaspar_format.txt
MEME format	MAFG.H12INVITRO.1.PSM.A_meme_format.meme
Transfac format	MAFG.H12INVITRO.1.PSM.A_transfac_format.txt
Homer format	MAFG.H12INVITRO.1.PSM.A_homer_format_0.001.txt MAFG.H12INVITRO.1.PSM.A_homer_format_0.0005.txt MAFG.H12INVITRO.1.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	730.75	531.75	394.75	775.75
02	943.0	270.0	501.0	719.0
03	117.0	288.0	20.0	2008.0
04	11.0	42.0	2379.0	1.0
05	33.0	2388.0	7.0	5.0
06	3.0	5.0	7.0	2418.0
07	13.0	0.0	2292.0	128.0
08	2411.0	14.0	0.0	8.0
09	51.0	1825.0	259.0	298.0
10	283.0	213.0	1089.0	848.0
11	522.0	583.0	261.0	1067.0
12	968.0	375.0	562.0	528.0
13	643.0	337.0	994.0	459.0
14	346.75	1020.75	605.75	459.75
15	712.25	591.25	642.25	487.25

PFM

	A	C	G	T
01	0.3	0.219	0.162	0.319
02	0.388	0.111	0.206	0.296
03	0.048	0.118	0.008	0.825
04	0.005	0.017	0.978	0.0
05	0.014	0.982	0.003	0.002
06	0.001	0.002	0.003	0.994
07	0.005	0.0	0.942	0.053
08	0.991	0.006	0.0	0.003
09	0.021	0.75	0.106	0.122
10	0.116	0.088	0.448	0.349
11	0.215	0.24	0.107	0.439
12	0.398	0.154	0.231	0.217
13	0.264	0.139	0.409	0.189
14	0.143	0.42	0.249	0.189
15	0.293	0.243	0.264	0.2

PWM

	A	C	G	T
01	0.183	-0.134	-0.431	0.243
02	0.437	-0.808	-0.193	0.167
03	-1.635	-0.744	-3.325	1.192
04	-3.853	-2.631	1.361	-5.332
05	-2.86	1.365	-4.222	-4.475
06	-4.815	-4.475	-4.222	1.378
07	-3.709	-5.746	1.324	-1.547
08	1.375	-3.644	-5.746	-4.116
09	-2.444	1.097	-0.849	-0.71
10	-0.761	-1.043	0.581	0.331
11	-0.152	-0.042	-0.842	0.561
12	0.463	-0.482	-0.079	-0.141
13	0.055	-0.588	0.49	-0.28
14	-0.56	0.516	-0.004	-0.279
15	0.157	-0.028	0.054	-0.221

Standard thresholds

P-value	Threshold
0.001	3.79571
0.0005	4.99506
0.0001	7.41001