| Motif | MAFG.H12INVITRO.0.PSM.A |
| Gene (human) | MAFG (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Mafg |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | MAFG.H12INVITRO.0.PSM.A |
| Gene (human) | MAFG (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Mafg |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 18 |
| Consensus | vdWWnTGCTGAbYYWGCW |
| GC content | 45.61% |
| Information content (bits; total / per base) | 16.856 / 0.936 |
| Data sources | ChIP-Seq + HT-SELEX + Methyl-HT-SELEX |
| Aligned words | 1003 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 2 (14) | 0.89 | 0.959 | 0.881 | 0.942 | 0.897 | 0.945 | 5.196 | 6.643 | 333.491 | 883.745 |
| Mouse | 2 (14) | 0.989 | 0.99 | 0.984 | 0.986 | 0.986 | 0.988 | 7.617 | 7.74 | 698.227 | 872.252 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 6 experiments | median | 0.985 | 0.977 | 0.934 | 0.93 | 0.79 | 0.805 |
| best | 1.0 | 1.0 | 0.962 | 0.95 | 0.898 | 0.879 | |
| Methyl HT-SELEX, 2 experiments | median | 0.965 | 0.951 | 0.898 | 0.88 | 0.786 | 0.782 |
| best | 0.987 | 0.982 | 0.953 | 0.94 | 0.853 | 0.845 | |
| Non-Methyl HT-SELEX, 4 experiments | median | 0.987 | 0.979 | 0.938 | 0.933 | 0.794 | 0.81 |
| best | 1.0 | 1.0 | 0.962 | 0.95 | 0.898 | 0.879 | |
| rSNP benchmarking, ADASTRA | odds-ratio | -log-Fisher's P | Pearson r | Kendall tau |
|---|---|---|---|---|
| # | 11.957 | 10.555 | 0.334 | 0.188 |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.905 | 0.455 | 0.902 | 0.575 |
| batch 2 | 0.689 | 0.418 | 0.742 | 0.547 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
| TF family | Maf-related {1.1.3} (TFClass) |
| TF subfamily | Small MAF {1.1.3.2} (TFClass) |
| TFClass ID | TFClass: 1.1.3.2.2 |
| HGNC | HGNC:6781 |
| MGI | MGI:96911 |
| EntrezGene (human) | GeneID:4097 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17134 (SSTAR profile) |
| UniProt ID (human) | MAFG_HUMAN |
| UniProt ID (mouse) | MAFG_MOUSE |
| UniProt AC (human) | O15525 (TFClass) |
| UniProt AC (mouse) | O54790 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 2 human, 2 mouse |
| HT-SELEX | 4 |
| Methyl-HT-SELEX | 2 |
| PCM | MAFG.H12INVITRO.0.PSM.A.pcm |
| PWM | MAFG.H12INVITRO.0.PSM.A.pwm |
| PFM | MAFG.H12INVITRO.0.PSM.A.pfm |
| Alignment | MAFG.H12INVITRO.0.PSM.A.words.tsv |
| Threshold to P-value map | MAFG.H12INVITRO.0.PSM.A.thr |
| Motif in other formats | |
| JASPAR format | MAFG.H12INVITRO.0.PSM.A_jaspar_format.txt |
| MEME format | MAFG.H12INVITRO.0.PSM.A_meme_format.meme |
| Transfac format | MAFG.H12INVITRO.0.PSM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 462.0 | 134.0 | 275.0 | 132.0 |
| 02 | 509.0 | 66.0 | 209.0 | 219.0 |
| 03 | 608.0 | 46.0 | 67.0 | 282.0 |
| 04 | 468.0 | 43.0 | 102.0 | 390.0 |
| 05 | 257.0 | 200.0 | 221.0 | 325.0 |
| 06 | 39.0 | 69.0 | 14.0 | 881.0 |
| 07 | 7.0 | 21.0 | 972.0 | 3.0 |
| 08 | 58.0 | 923.0 | 6.0 | 16.0 |
| 09 | 12.0 | 8.0 | 6.0 | 977.0 |
| 10 | 1.0 | 5.0 | 979.0 | 18.0 |
| 11 | 966.0 | 20.0 | 4.0 | 13.0 |
| 12 | 76.0 | 428.0 | 417.0 | 82.0 |
| 13 | 87.0 | 88.0 | 48.0 | 780.0 |
| 14 | 111.0 | 694.0 | 65.0 | 133.0 |
| 15 | 732.0 | 18.0 | 117.0 | 136.0 |
| 16 | 65.0 | 22.0 | 802.0 | 114.0 |
| 17 | 33.0 | 834.0 | 105.0 | 31.0 |
| 18 | 678.0 | 113.0 | 93.0 | 119.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.461 | 0.134 | 0.274 | 0.132 |
| 02 | 0.507 | 0.066 | 0.208 | 0.218 |
| 03 | 0.606 | 0.046 | 0.067 | 0.281 |
| 04 | 0.467 | 0.043 | 0.102 | 0.389 |
| 05 | 0.256 | 0.199 | 0.22 | 0.324 |
| 06 | 0.039 | 0.069 | 0.014 | 0.878 |
| 07 | 0.007 | 0.021 | 0.969 | 0.003 |
| 08 | 0.058 | 0.92 | 0.006 | 0.016 |
| 09 | 0.012 | 0.008 | 0.006 | 0.974 |
| 10 | 0.001 | 0.005 | 0.976 | 0.018 |
| 11 | 0.963 | 0.02 | 0.004 | 0.013 |
| 12 | 0.076 | 0.427 | 0.416 | 0.082 |
| 13 | 0.087 | 0.088 | 0.048 | 0.778 |
| 14 | 0.111 | 0.692 | 0.065 | 0.133 |
| 15 | 0.73 | 0.018 | 0.117 | 0.136 |
| 16 | 0.065 | 0.022 | 0.8 | 0.114 |
| 17 | 0.033 | 0.832 | 0.105 | 0.031 |
| 18 | 0.676 | 0.113 | 0.093 | 0.119 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.608 | -0.621 | 0.092 | -0.636 |
| 02 | 0.705 | -1.316 | -0.181 | -0.134 |
| 03 | 0.882 | -1.666 | -1.301 | 0.117 |
| 04 | 0.621 | -1.731 | -0.89 | 0.439 |
| 05 | 0.024 | -0.224 | -0.125 | 0.258 |
| 06 | -1.824 | -1.272 | -2.776 | 1.252 |
| 07 | -3.365 | -2.408 | 1.35 | -3.978 |
| 08 | -1.442 | 1.298 | -3.487 | -2.656 |
| 09 | -2.912 | -3.256 | -3.487 | 1.355 |
| 10 | -4.528 | -3.625 | 1.357 | -2.549 |
| 11 | 1.344 | -2.453 | -3.786 | -2.842 |
| 12 | -1.178 | 0.532 | 0.506 | -1.104 |
| 13 | -1.046 | -1.035 | -1.625 | 1.13 |
| 14 | -0.806 | 1.014 | -1.331 | -0.628 |
| 15 | 1.067 | -2.549 | -0.754 | -0.606 |
| 16 | -1.331 | -2.365 | 1.158 | -0.78 |
| 17 | -1.984 | 1.197 | -0.861 | -2.043 |
| 18 | 0.99 | -0.789 | -0.98 | -0.738 |
| P-value | Threshold |
|---|---|
| 0.001 | 2.34861 |
| 0.0005 | 3.55326 |
| 0.0001 | 6.09301 |