MotifMAFF.H12INVIVO.0.PSM.A
Gene (human)MAFF
(GeneCards)
Gene synonyms (human)
Gene (mouse)Maff
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length22
ConsensusdhhhKGCYKRSTCAGCWnWYYh
GC content43.66%
Information content (bits; total / per base)17.272 / 0.785
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words927

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 2 (14) 0.961 0.972 0.949 0.963 0.956 0.97 6.549 7.122 850.256 1020.367
Mouse 7 (48) 0.931 0.961 0.915 0.948 0.926 0.954 6.297 7.524 332.663 686.367

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.982 0.978 0.906 0.904 0.788 0.8
best 0.999 0.999 0.997 0.996 0.957 0.954
Methyl HT-SELEX, 2 experiments median 0.982 0.978 0.906 0.904 0.788 0.8
best 0.999 0.998 0.989 0.986 0.898 0.899
Non-Methyl HT-SELEX, 2 experiments median 0.778 0.779 0.764 0.764 0.737 0.737
best 0.999 0.999 0.997 0.996 0.957 0.954

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.791 0.697 0.771 0.59
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyMaf-related {1.1.3} (TFClass)
TF subfamilySmall MAF {1.1.3.2} (TFClass)
TFClass IDTFClass: 1.1.3.2.1
HGNCHGNC:6780
MGIMGI:96910
EntrezGene (human)GeneID:23764
(SSTAR profile)
EntrezGene (mouse)GeneID:17133
(SSTAR profile)
UniProt ID (human)MAFF_HUMAN
UniProt ID (mouse)MAFF_MOUSE
UniProt AC (human)Q9ULX9
(TFClass)
UniProt AC (mouse)O54791
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 2 human, 7 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01343.0125.0141.0318.0
02358.0100.068.0401.0
03249.0117.0106.0455.0
04159.0260.0143.0365.0
0575.074.078.0700.0
0626.081.0791.029.0
0759.0790.022.056.0
08104.0126.027.0670.0
09115.059.0632.0121.0
10707.046.0103.071.0
1153.0341.0506.027.0
1213.06.014.0894.0
1340.0866.013.08.0
14891.02.021.013.0
155.012.0792.0118.0
166.0861.034.026.0
17721.035.072.099.0
18184.0240.0177.0326.0
19181.082.084.0580.0
20142.0150.051.0584.0
21111.0253.045.0518.0
22143.0241.0117.0426.0
PFM
ACGT
010.370.1350.1520.343
020.3860.1080.0730.433
030.2690.1260.1140.491
040.1720.280.1540.394
050.0810.080.0840.755
060.0280.0870.8530.031
070.0640.8520.0240.06
080.1120.1360.0290.723
090.1240.0640.6820.131
100.7630.050.1110.077
110.0570.3680.5460.029
120.0140.0060.0150.964
130.0430.9340.0140.009
140.9610.0020.0230.014
150.0050.0130.8540.127
160.0060.9290.0370.028
170.7780.0380.0780.107
180.1980.2590.1910.352
190.1950.0880.0910.626
200.1530.1620.0550.63
210.120.2730.0490.559
220.1540.260.1260.46
PWM
ACGT
010.39-0.611-0.4920.314
020.432-0.831-1.2090.545
030.071-0.676-0.7740.671
04-0.3730.114-0.4780.452
05-1.113-1.126-1.0751.101
06-2.131-1.0381.222-2.028
07-1.3471.221-2.287-1.398
08-0.792-0.603-2.0961.057
09-0.693-1.3470.999-0.643
101.11-1.588-0.802-1.167
11-1.4510.3840.777-2.096
12-2.765-3.411-2.6991.345
13-1.7221.313-2.765-3.18
141.341-4.143-2.33-2.765
15-3.55-2.8351.224-0.668
16-3.4111.307-1.878-2.131
171.13-1.85-1.153-0.841
18-0.2290.035-0.2670.339
19-0.245-1.026-1.0020.913
20-0.485-0.431-1.4880.92
21-0.7280.087-1.6090.8
22-0.4780.039-0.6760.605
Standard thresholds
P-value Threshold
0.001 2.46096
0.0005 3.61511
0.0001 6.06321