MAFF.H12CORE.1.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFF.H12CORE.1.PSM.A
Gene (human)	MAFF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Maff
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	14
Consensus	dhSTCAGCAhdhhn
GC content	47.32%
Information content (bits; total / per base)	13.001 / 0.929
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	2493

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (14)	0.958	0.972	0.929	0.948	0.938	0.958	4.575	4.909	793.093	939.602
Mouse	7 (48)	0.917	0.958	0.884	0.935	0.901	0.946	4.182	4.856	299.316	629.119

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.996	0.994	0.988	0.984	0.944	0.935
Overall, 4 experiments	best	0.999	0.998	0.998	0.996	0.994	0.991
Methyl HT-SELEX, 2 experiments	median	0.996	0.994	0.988	0.984	0.944	0.935
Methyl HT-SELEX, 2 experiments	best	0.998	0.997	0.99	0.987	0.948	0.938
Non-Methyl HT-SELEX, 2 experiments	median	0.762	0.769	0.751	0.756	0.746	0.749
Non-Methyl HT-SELEX, 2 experiments	best	0.999	0.998	0.998	0.996	0.994	0.991

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.756	0.681	0.726	0.533

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Small MAF {1.1.3.2} (TFClass)
TFClass ID	TFClass: 1.1.3.2.1
HGNC	HGNC:6780
MGI	MGI:96910
EntrezGene (human)	GeneID:23764 (SSTAR profile)
EntrezGene (mouse)	GeneID:17133 (SSTAR profile)
UniProt ID (human)	MAFF_HUMAN
UniProt ID (mouse)	MAFF_MOUSE
UniProt AC (human)	Q9ULX9 (TFClass)
UniProt AC (mouse)	O54791 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 7 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	MAFF.H12CORE.1.PSM.A.pcm
PWM	MAFF.H12CORE.1.PSM.A.pwm
PFM	MAFF.H12CORE.1.PSM.A.pfm
Alignment	MAFF.H12CORE.1.PSM.A.words.tsv
Threshold to P-value map	MAFF.H12CORE.1.PSM.A.thr
Motif in other formats
JASPAR format	MAFF.H12CORE.1.PSM.A_jaspar_format.txt
MEME format	MAFF.H12CORE.1.PSM.A_meme_format.meme
Transfac format	MAFF.H12CORE.1.PSM.A_transfac_format.txt
Homer format	MAFF.H12CORE.1.PSM.A_homer_format_0.001.txt MAFF.H12CORE.1.PSM.A_homer_format_0.0005.txt MAFF.H12CORE.1.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	533.25	292.25	1268.25	399.25
02	1336.75	582.75	234.75	338.75
03	208.0	1063.0	1177.0	45.0
04	1.0	3.0	2.0	2487.0
05	4.0	2489.0	0.0	0.0
06	2486.0	0.0	7.0	0.0
07	0.0	1.0	2491.0	1.0
08	0.0	2491.0	2.0	0.0
09	1850.0	1.0	601.0	41.0
10	848.0	443.0	363.0	839.0
11	1053.0	206.0	217.0	1017.0
12	854.0	258.0	245.0	1136.0
13	547.25	498.25	357.25	1090.25
14	441.5	604.5	617.5	829.5

PFM

	A	C	G	T
01	0.214	0.117	0.509	0.16
02	0.536	0.234	0.094	0.136
03	0.083	0.426	0.472	0.018
04	0.0	0.001	0.001	0.998
05	0.002	0.998	0.0	0.0
06	0.997	0.0	0.003	0.0
07	0.0	0.0	0.999	0.0
08	0.0	0.999	0.001	0.0
09	0.742	0.0	0.241	0.016
10	0.34	0.178	0.146	0.337
11	0.422	0.083	0.087	0.408
12	0.343	0.103	0.098	0.456
13	0.22	0.2	0.143	0.437
14	0.177	0.242	0.248	0.333

PWM

	A	C	G	T
01	-0.155	-0.754	0.709	-0.444
02	0.761	-0.067	-0.971	-0.607
03	-1.091	0.533	0.634	-2.589
04	-5.354	-4.838	-5.063	1.382
05	-4.654	1.382	-5.768	-5.768
06	1.381	-5.768	-4.246	-5.768
07	-5.768	-5.354	1.383	-5.354
08	-5.768	1.383	-5.063	-5.768
09	1.086	-5.354	-0.036	-2.678
10	0.307	-0.34	-0.538	0.296
11	0.523	-1.101	-1.049	0.488
12	0.314	-0.878	-0.929	0.599
13	-0.13	-0.223	-0.554	0.558
14	-0.343	-0.03	-0.009	0.285

Standard thresholds

P-value	Threshold
0.001	2.38806
0.0005	3.93531
0.0001	7.51146