MAFB.H12RSNP.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFB.H12RSNP.0.PS.A
Gene (human)	MAFB (GeneCards)
Gene synonyms (human)	KRML
Gene (mouse)	Mafb
Gene synonyms (mouse)	Krml, Maf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	20
Consensus	dhdnTGCTGACTCAGCAhhh
GC content	46.25%
Information content (bits; total / per base)	26.065 / 1.303
Data sources	ChIP-Seq + HT-SELEX
Aligned words	670

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (16)	0.551	0.566	0.451	0.482	0.765	0.785	2.811	3.158	178.959	264.167

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.923	0.923	0.837	0.845	0.731	0.75
Non-Methyl HT-SELEX, 2 experiments	best	1.0	1.0	0.995	0.994	0.873	0.886

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.63	0.02	0.012	0.059

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Large MAF {1.1.3.1} (TFClass)
TFClass ID	TFClass: 1.1.3.1.3
HGNC	HGNC:6408
MGI	MGI:104555
EntrezGene (human)	GeneID:9935 (SSTAR profile)
EntrezGene (mouse)	GeneID:16658 (SSTAR profile)
UniProt ID (human)	MAFB_HUMAN
UniProt ID (mouse)	MAFB_MOUSE
UniProt AC (human)	Q9Y5Q3 (TFClass)
UniProt AC (mouse)	P54841 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MAFB.H12RSNP.0.PS.A.pcm
PWM	MAFB.H12RSNP.0.PS.A.pwm
PFM	MAFB.H12RSNP.0.PS.A.pfm
Alignment	MAFB.H12RSNP.0.PS.A.words.tsv
Threshold to P-value map	MAFB.H12RSNP.0.PS.A.thr
Motif in other formats
JASPAR format	MAFB.H12RSNP.0.PS.A_jaspar_format.txt
MEME format	MAFB.H12RSNP.0.PS.A_meme_format.meme
Transfac format	MAFB.H12RSNP.0.PS.A_transfac_format.txt
Homer format	MAFB.H12RSNP.0.PS.A_homer_format_0.001.txt MAFB.H12RSNP.0.PS.A_homer_format_0.0005.txt MAFB.H12RSNP.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	269.5	119.5	124.5	156.5
02	333.0	84.0	77.0	176.0
03	359.0	57.0	60.0	194.0
04	237.0	94.0	148.0	191.0
05	1.0	93.0	0.0	576.0
06	0.0	0.0	670.0	0.0
07	0.0	670.0	0.0	0.0
08	0.0	0.0	0.0	670.0
09	0.0	0.0	670.0	0.0
10	670.0	0.0	0.0	0.0
11	0.0	663.0	7.0	0.0
12	0.0	0.0	1.0	669.0
13	0.0	669.0	0.0	1.0
14	669.0	1.0	0.0	0.0
15	1.0	0.0	669.0	0.0
16	0.0	669.0	1.0	0.0
17	594.0	1.0	72.0	3.0
18	174.0	167.0	74.0	255.0
19	175.25	90.25	71.25	333.25
20	195.5	97.5	77.5	299.5

PFM

	A	C	G	T
01	0.402	0.178	0.186	0.234
02	0.497	0.125	0.115	0.263
03	0.536	0.085	0.09	0.29
04	0.354	0.14	0.221	0.285
05	0.001	0.139	0.0	0.86
06	0.0	0.0	1.0	0.0
07	0.0	1.0	0.0	0.0
08	0.0	0.0	0.0	1.0
09	0.0	0.0	1.0	0.0
10	1.0	0.0	0.0	0.0
11	0.0	0.99	0.01	0.0
12	0.0	0.0	0.001	0.999
13	0.0	0.999	0.0	0.001
14	0.999	0.001	0.0	0.0
15	0.001	0.0	0.999	0.0
16	0.0	0.999	0.001	0.0
17	0.887	0.001	0.107	0.004
18	0.26	0.249	0.11	0.381
19	0.262	0.135	0.106	0.497
20	0.292	0.146	0.116	0.447

PWM

	A	C	G	T
01	0.472	-0.334	-0.293	-0.067
02	0.682	-0.681	-0.766	0.049
03	0.757	-1.059	-1.01	0.146
04	0.344	-0.57	-0.123	0.13
05	-4.165	-0.581	-4.644	1.228
06	-4.644	-4.644	1.379	-4.644
07	-4.644	1.379	-4.644	-4.644
08	-4.644	-4.644	-4.644	1.379
09	-4.644	-4.644	1.379	-4.644
10	1.379	-4.644	-4.644	-4.644
11	-4.644	1.369	-2.976	-4.644
12	-4.644	-4.644	-4.165	1.378
13	-4.644	1.378	-4.644	-4.165
14	1.378	-4.165	-4.644	-4.644
15	-4.165	-4.644	1.378	-4.644
16	-4.644	1.378	-4.165	-4.644
17	1.259	-4.165	-0.832	-3.599
18	0.038	-0.003	-0.805	0.417
19	0.045	-0.61	-0.842	0.683
20	0.153	-0.534	-0.76	0.577

Standard thresholds

P-value	Threshold
0.001	-7.29649
0.0005	-5.45224
0.0001	-0.88934