MAFB.H12INVIVO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFB.H12INVIVO.1.P.B
Gene (human)	MAFB (GeneCards)
Gene synonyms (human)	KRML
Gene (mouse)	Mafb
Gene synonyms (mouse)	Krml, Maf1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	10
Consensus	hnTGCTGAbh
GC content	49.15%
Information content (bits; total / per base)	9.394 / 0.939
Data sources	ChIP-Seq
Aligned words	989

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (16)	0.868	0.883	0.771	0.793	0.828	0.844	2.629	2.781	246.203	401.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.927	0.918	0.846	0.846	0.743	0.758
Non-Methyl HT-SELEX, 2 experiments	best	0.996	0.994	0.992	0.988	0.883	0.893

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.498	0.012	0.349	0.312

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Large MAF {1.1.3.1} (TFClass)
TFClass ID	TFClass: 1.1.3.1.3
HGNC	HGNC:6408
MGI	MGI:104555
EntrezGene (human)	GeneID:9935 (SSTAR profile)
EntrezGene (mouse)	GeneID:16658 (SSTAR profile)
UniProt ID (human)	MAFB_HUMAN
UniProt ID (mouse)	MAFB_MOUSE
UniProt AC (human)	Q9Y5Q3 (TFClass)
UniProt AC (mouse)	P54841 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MAFB.H12INVIVO.1.P.B.pcm
PWM	MAFB.H12INVIVO.1.P.B.pwm
PFM	MAFB.H12INVIVO.1.P.B.pfm
Alignment	MAFB.H12INVIVO.1.P.B.words.tsv
Threshold to P-value map	MAFB.H12INVIVO.1.P.B.thr
Motif in other formats
JASPAR format	MAFB.H12INVIVO.1.P.B_jaspar_format.txt
MEME format	MAFB.H12INVIVO.1.P.B_meme_format.meme
Transfac format	MAFB.H12INVIVO.1.P.B_transfac_format.txt
Homer format	MAFB.H12INVIVO.1.P.B_homer_format_0.001.txt MAFB.H12INVIVO.1.P.B_homer_format_0.0005.txt MAFB.H12INVIVO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	409.0	147.0	115.0	318.0
02	205.0	294.0	203.0	287.0
03	90.0	38.0	45.0	816.0
04	15.0	30.0	921.0	23.0
05	37.0	944.0	6.0	2.0
06	36.0	5.0	2.0	946.0
07	12.0	19.0	891.0	67.0
08	852.0	18.0	47.0	72.0
09	51.0	505.0	309.0	124.0
10	213.0	185.0	137.0	454.0

PFM

	A	C	G	T
01	0.414	0.149	0.116	0.322
02	0.207	0.297	0.205	0.29
03	0.091	0.038	0.046	0.825
04	0.015	0.03	0.931	0.023
05	0.037	0.954	0.006	0.002
06	0.036	0.005	0.002	0.957
07	0.012	0.019	0.901	0.068
08	0.861	0.018	0.048	0.073
09	0.052	0.511	0.312	0.125
10	0.215	0.187	0.139	0.459

PWM

	A	C	G	T
01	0.501	-0.515	-0.758	0.25
02	-0.186	0.172	-0.196	0.148
03	-0.999	-1.835	-1.673	1.189
04	-2.7	-2.06	1.31	-2.31
05	-1.861	1.335	-3.473	-4.203
06	-1.887	-3.612	-4.203	1.337
07	-2.898	-2.486	1.277	-1.287
08	1.232	-2.536	-1.631	-1.217
09	-1.552	0.711	0.222	-0.683
10	-0.148	-0.288	-0.585	0.605

Standard thresholds

P-value	Threshold
0.001	4.9031
0.0005	5.6436
0.0001	7.397695