MAFB.H12INVIVO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFB.H12INVIVO.0.PS.A
Gene (human)	MAFB (GeneCards)
Gene synonyms (human)	KRML
Gene (mouse)	Mafb
Gene synonyms (mouse)	Krml, Maf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	TGCTGAShhdRv
GC content	53.33%
Information content (bits; total / per base)	11.523 / 0.96
Data sources	ChIP-Seq + HT-SELEX
Aligned words	997

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (16)	0.886	0.902	0.806	0.831	0.852	0.868	3.076	3.419	279.254	424.398

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.939	0.936	0.848	0.856	0.744	0.764
Non-Methyl HT-SELEX, 2 experiments	best	1.0	0.999	0.997	0.996	0.889	0.903

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.472	0.012	-0.032	0.012

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Large MAF {1.1.3.1} (TFClass)
TFClass ID	TFClass: 1.1.3.1.3
HGNC	HGNC:6408
MGI	MGI:104555
EntrezGene (human)	GeneID:9935 (SSTAR profile)
EntrezGene (mouse)	GeneID:16658 (SSTAR profile)
UniProt ID (human)	MAFB_HUMAN
UniProt ID (mouse)	MAFB_MOUSE
UniProt AC (human)	Q9Y5Q3 (TFClass)
UniProt AC (mouse)	P54841 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MAFB.H12INVIVO.0.PS.A.pcm
PWM	MAFB.H12INVIVO.0.PS.A.pwm
PFM	MAFB.H12INVIVO.0.PS.A.pfm
Alignment	MAFB.H12INVIVO.0.PS.A.words.tsv
Threshold to P-value map	MAFB.H12INVIVO.0.PS.A.thr
Motif in other formats
JASPAR format	MAFB.H12INVIVO.0.PS.A_jaspar_format.txt
MEME format	MAFB.H12INVIVO.0.PS.A_meme_format.meme
Transfac format	MAFB.H12INVIVO.0.PS.A_transfac_format.txt
Homer format	MAFB.H12INVIVO.0.PS.A_homer_format_0.001.txt MAFB.H12INVIVO.0.PS.A_homer_format_0.0005.txt MAFB.H12INVIVO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	82.0	23.0	12.0	880.0
02	2.0	6.0	980.0	9.0
03	42.0	950.0	0.0	5.0
04	21.0	3.0	0.0	973.0
05	8.0	10.0	931.0	48.0
06	933.0	8.0	17.0	39.0
07	38.0	547.0	302.0	110.0
08	240.0	159.0	122.0	476.0
09	188.0	439.0	156.0	214.0
10	456.0	121.0	198.0	222.0
11	209.0	57.0	604.0	127.0
12	135.0	466.0	269.0	127.0

PFM

	A	C	G	T
01	0.082	0.023	0.012	0.883
02	0.002	0.006	0.983	0.009
03	0.042	0.953	0.0	0.005
04	0.021	0.003	0.0	0.976
05	0.008	0.01	0.934	0.048
06	0.936	0.008	0.017	0.039
07	0.038	0.549	0.303	0.11
08	0.241	0.159	0.122	0.477
09	0.189	0.44	0.156	0.215
10	0.457	0.121	0.199	0.223
11	0.21	0.057	0.606	0.127
12	0.135	0.467	0.27	0.127

PWM

	A	C	G	T
01	-1.098	-2.317	-2.906	1.257
02	-4.21	-3.481	1.364	-3.153
03	-1.747	1.333	-4.979	-3.619
04	-2.402	-3.972	-4.979	1.357
05	-3.251	-3.064	1.313	-1.619
06	1.315	-3.251	-2.595	-1.818
07	-1.843	0.782	0.191	-0.809
08	-0.038	-0.446	-0.707	0.644
09	-0.28	0.563	-0.464	-0.151
10	0.601	-0.715	-0.228	-0.115
11	-0.175	-1.452	0.881	-0.668
12	-0.607	0.623	0.076	-0.668

Standard thresholds

P-value	Threshold
0.001	4.270465
0.0005	5.256735
0.0001	7.35507