MAFB.H12INVITRO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFB.H12INVITRO.1.P.B
Gene (human)	MAFB (GeneCards)
Gene synonyms (human)	KRML
Gene (mouse)	Mafb
Gene synonyms (mouse)	Krml, Maf1
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	10
Consensus	hnTGCTGASh
GC content	49.45%
Information content (bits; total / per base)	11.119 / 1.112
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (16)	0.862	0.881	0.759	0.787	0.826	0.845	2.618	2.784	244.131	407.509

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.928	0.918	0.849	0.847	0.75	0.761
Non-Methyl HT-SELEX, 2 experiments	best	0.997	0.994	0.992	0.988	0.887	0.895

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.537	0.013	0.195	0.196

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Large MAF {1.1.3.1} (TFClass)
TFClass ID	TFClass: 1.1.3.1.3
HGNC	HGNC:6408
MGI	MGI:104555
EntrezGene (human)	GeneID:9935 (SSTAR profile)
EntrezGene (mouse)	GeneID:16658 (SSTAR profile)
UniProt ID (human)	MAFB_HUMAN
UniProt ID (mouse)	MAFB_MOUSE
UniProt AC (human)	Q9Y5Q3 (TFClass)
UniProt AC (mouse)	P54841 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MAFB.H12INVITRO.1.P.B.pcm
PWM	MAFB.H12INVITRO.1.P.B.pwm
PFM	MAFB.H12INVITRO.1.P.B.pfm
Alignment	MAFB.H12INVITRO.1.P.B.words.tsv
Threshold to P-value map	MAFB.H12INVITRO.1.P.B.thr
Motif in other formats
JASPAR format	MAFB.H12INVITRO.1.P.B_jaspar_format.txt
MEME format	MAFB.H12INVITRO.1.P.B_meme_format.meme
Transfac format	MAFB.H12INVITRO.1.P.B_transfac_format.txt
Homer format	MAFB.H12INVITRO.1.P.B_homer_format_0.001.txt MAFB.H12INVITRO.1.P.B_homer_format_0.0005.txt MAFB.H12INVITRO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	439.0	129.0	102.0	330.0
02	182.0	317.0	227.0	274.0
03	76.0	33.0	8.0	883.0
04	2.0	7.0	990.0	1.0
05	5.0	987.0	3.0	5.0
06	29.0	1.0	0.0	970.0
07	4.0	7.0	959.0	30.0
08	919.0	7.0	21.0	53.0
09	40.0	557.0	311.0	92.0
10	231.0	162.0	117.0	490.0

PFM

	A	C	G	T
01	0.439	0.129	0.102	0.33
02	0.182	0.317	0.227	0.274
03	0.076	0.033	0.008	0.883
04	0.002	0.007	0.99	0.001
05	0.005	0.987	0.003	0.005
06	0.029	0.001	0.0	0.97
07	0.004	0.007	0.959	0.03
08	0.919	0.007	0.021	0.053
09	0.04	0.557	0.311	0.092
10	0.231	0.162	0.117	0.49

PWM

	A	C	G	T
01	0.56	-0.655	-0.887	0.276
02	-0.315	0.236	-0.096	0.091
03	-1.175	-1.981	-3.253	1.257
04	-4.213	-3.362	1.371	-4.525
05	-3.622	1.368	-3.975	-3.622
06	-2.103	-4.525	-4.982	1.351
07	-3.783	-3.362	1.339	-2.071
08	1.297	-3.362	-2.405	-1.526
09	-1.797	0.797	0.217	-0.988
10	-0.078	-0.43	-0.752	0.67

Standard thresholds

P-value	Threshold
0.001	4.341655
0.0005	5.334325
0.0001	7.56519