MAFB.H12CORE.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFB.H12CORE.0.PS.A
Gene (human)	MAFB (GeneCards)
Gene synonyms (human)	KRML
Gene (mouse)	Mafb
Gene synonyms (mouse)	Krml, Maf1
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	20
Consensus	ddTGCTGASKYMRSvddWhb
GC content	45.08%
Information content (bits; total / per base)	16.477 / 0.824
Data sources	ChIP-Seq + HT-SELEX
Aligned words	9525

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	3 (16)	0.883	0.899	0.799	0.829	0.844	0.862	3.012	3.382	240.241	378.886

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.944	0.943	0.851	0.86	0.745	0.767
Non-Methyl HT-SELEX, 2 experiments	best	1.0	1.0	0.999	0.999	0.888	0.903

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.548	0.017	-0.059	0.009

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Large MAF {1.1.3.1} (TFClass)
TFClass ID	TFClass: 1.1.3.1.3
HGNC	HGNC:6408
MGI	MGI:104555
EntrezGene (human)	GeneID:9935 (SSTAR profile)
EntrezGene (mouse)	GeneID:16658 (SSTAR profile)
UniProt ID (human)	MAFB_HUMAN
UniProt ID (mouse)	MAFB_MOUSE
UniProt AC (human)	Q9Y5Q3 (TFClass)
UniProt AC (mouse)	P54841 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 3 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	MAFB.H12CORE.0.PS.A.pcm
PWM	MAFB.H12CORE.0.PS.A.pwm
PFM	MAFB.H12CORE.0.PS.A.pfm
Alignment	MAFB.H12CORE.0.PS.A.words.tsv
Threshold to P-value map	MAFB.H12CORE.0.PS.A.thr
Motif in other formats
JASPAR format	MAFB.H12CORE.0.PS.A_jaspar_format.txt
MEME format	MAFB.H12CORE.0.PS.A_meme_format.meme
Transfac format	MAFB.H12CORE.0.PS.A_transfac_format.txt
Homer format	MAFB.H12CORE.0.PS.A_homer_format_0.001.txt MAFB.H12CORE.0.PS.A_homer_format_0.0005.txt MAFB.H12CORE.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	5375.5	962.5	1011.5	2175.5
02	4089.0	1055.0	2223.0	2158.0
03	518.0	1296.0	70.0	7641.0
04	28.0	60.0	9423.0	14.0
05	411.0	8955.0	32.0	127.0
06	71.0	142.0	47.0	9265.0
07	100.0	6.0	8997.0	422.0
08	9158.0	238.0	5.0	124.0
09	141.0	6444.0	2653.0	287.0
10	438.0	43.0	3226.0	5818.0
11	902.0	5565.0	76.0	2982.0
12	6749.0	1341.0	703.0	732.0
13	1727.0	170.0	6666.0	962.0
14	282.0	6645.0	1901.0	697.0
15	4745.0	2177.0	1741.0	862.0
16	3655.0	1543.0	1737.0	2590.0
17	3319.0	1030.0	1047.0	4129.0
18	2506.0	507.0	483.0	6029.0
19	1930.75	1295.75	894.75	5403.75
20	1664.75	1755.75	1710.75	4393.75

PFM

	A	C	G	T
01	0.564	0.101	0.106	0.228
02	0.429	0.111	0.233	0.227
03	0.054	0.136	0.007	0.802
04	0.003	0.006	0.989	0.001
05	0.043	0.94	0.003	0.013
06	0.007	0.015	0.005	0.973
07	0.01	0.001	0.945	0.044
08	0.961	0.025	0.001	0.013
09	0.015	0.677	0.279	0.03
10	0.046	0.005	0.339	0.611
11	0.095	0.584	0.008	0.313
12	0.709	0.141	0.074	0.077
13	0.181	0.018	0.7	0.101
14	0.03	0.698	0.2	0.073
15	0.498	0.229	0.183	0.09
16	0.384	0.162	0.182	0.272
17	0.348	0.108	0.11	0.433
18	0.263	0.053	0.051	0.633
19	0.203	0.136	0.094	0.567
20	0.175	0.184	0.18	0.461

PWM

	A	C	G	T
01	0.814	-0.904	-0.855	-0.09
02	0.54	-0.813	-0.069	-0.098
03	-1.522	-0.608	-3.496	1.165
04	-4.366	-3.645	1.375	-4.986
05	-1.752	1.324	-4.241	-2.914
06	-3.482	-2.805	-3.879	1.358
07	-3.149	-5.661	1.329	-1.726
08	1.346	-2.294	-5.79	-2.938
09	-2.811	0.995	0.108	-2.109
10	-1.689	-3.963	0.303	0.893
11	-0.969	0.848	-3.416	0.225
12	1.041	-0.573	-1.218	-1.177
13	-0.321	-2.627	1.029	-0.905
14	-2.126	1.026	-0.225	-1.226
15	0.689	-0.09	-0.313	-1.014
16	0.428	-0.433	-0.315	0.084
17	0.332	-0.837	-0.82	0.55
18	0.051	-1.543	-1.592	0.928
19	-0.209	-0.608	-0.977	0.819
20	-0.358	-0.304	-0.33	0.612

Standard thresholds

P-value	Threshold
0.001	2.13226
0.0005	3.41446
0.0001	6.08601