MotifMAFA.H12INVIVO.1.M.C
Gene (human)MAFA
(GeneCards)
Gene synonyms (human)
Gene (mouse)Mafa
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length19
ConsensusndWhnTGCTGACTCAGCdn
GC content49.59%
Information content (bits; total / per base)19.187 / 1.01
Data sourcesMethyl-HT-SELEX
Aligned words1055

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.724 0.748 0.648 0.65 0.695 0.742 2.255 2.329 77.509 100.337

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.997 0.996 0.987 0.982 0.922 0.917
best 0.997 0.996 0.99 0.986 0.939 0.933
Methyl HT-SELEX, 1 experiments median 0.997 0.996 0.984 0.979 0.905 0.901
best 0.997 0.996 0.984 0.979 0.905 0.901
Non-Methyl HT-SELEX, 1 experiments median 0.997 0.996 0.99 0.986 0.939 0.933
best 0.997 0.996 0.99 0.986 0.939 0.933

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.649 0.322 0.568 0.351
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyMaf-related {1.1.3} (TFClass)
TF subfamilyLarge MAF {1.1.3.1} (TFClass)
TFClass IDTFClass: 1.1.3.1.2
HGNCHGNC:23145
MGIMGI:2673307
EntrezGene (human)GeneID:389692
(SSTAR profile)
EntrezGene (mouse)GeneID:378435
(SSTAR profile)
UniProt ID (human)MAFA_HUMAN
UniProt ID (mouse)MAFA_MOUSE
UniProt AC (human)Q8NHW3
(TFClass)
UniProt AC (mouse)Q8CF90
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
01348.5217.5265.5223.5
02487.25115.25210.25242.25
03514.066.075.0400.0
04482.0116.055.0402.0
05288.0186.0214.0367.0
0619.0227.04.0805.0
071.00.01054.00.0
080.01055.00.00.0
090.00.00.01055.0
100.00.01055.00.0
111055.00.00.00.0
121.0852.0188.014.0
1358.018.0133.0846.0
1460.0882.018.095.0
15847.072.0102.034.0
1686.034.0874.061.0
1718.0896.0107.034.0
18569.25104.25263.25118.25
19326.0242.0240.0247.0
PFM
ACGT
010.330.2060.2520.212
020.4620.1090.1990.23
030.4870.0630.0710.379
040.4570.110.0520.381
050.2730.1760.2030.348
060.0180.2150.0040.763
070.0010.00.9990.0
080.01.00.00.0
090.00.00.01.0
100.00.01.00.0
111.00.00.00.0
120.0010.8080.1780.013
130.0550.0170.1260.802
140.0570.8360.0170.09
150.8030.0680.0970.032
160.0820.0320.8280.058
170.0170.8490.1010.032
180.540.0990.250.112
190.3090.2290.2270.234
PWM
ACGT
010.277-0.1910.007-0.164
020.611-0.819-0.225-0.084
030.664-1.366-1.2410.414
040.6-0.813-1.5430.419
050.087-0.347-0.2080.329
06-2.549-0.149-3.8341.111
07-4.574-5.0281.38-5.028
08-5.0281.381-5.028-5.028
09-5.028-5.028-5.0281.381
10-5.028-5.0281.381-5.028
111.381-5.028-5.028-5.028
12-4.5741.168-0.336-2.825
13-1.492-2.599-0.6781.161
14-1.4591.203-2.599-1.01
151.162-1.281-0.94-2.005
16-1.107-2.0051.193-1.443
17-2.5991.218-0.893-2.005
180.766-0.918-0.002-0.794
190.211-0.085-0.094-0.065
Standard thresholds
P-value Threshold
0.001 -0.26309
0.0005 1.34266
0.0001 4.70976