MotifMAFA.H12INVIVO.0.PSM.A
Gene (human)MAFA
(GeneCards)
Gene synonyms (human)
Gene (mouse)Mafa
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length18
ConsensusnddhnYGCTGASdhndvn
GC content49.47%
Information content (bits; total / per base)12.457 / 0.692
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words9900

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (5) 0.756 0.795 0.69 0.708 0.714 0.766 2.299 2.43 95.469 102.62

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.998 0.997 0.992 0.989 0.942 0.938
best 0.998 0.998 0.994 0.992 0.956 0.951
Methyl HT-SELEX, 1 experiments median 0.998 0.997 0.99 0.987 0.928 0.924
best 0.998 0.997 0.99 0.987 0.928 0.924
Non-Methyl HT-SELEX, 1 experiments median 0.998 0.998 0.994 0.992 0.956 0.951
best 0.998 0.998 0.994 0.992 0.956 0.951

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.657 0.344 0.574 0.355
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyMaf-related {1.1.3} (TFClass)
TF subfamilyLarge MAF {1.1.3.1} (TFClass)
TFClass IDTFClass: 1.1.3.1.2
HGNCHGNC:23145
MGIMGI:2673307
EntrezGene (human)GeneID:389692
(SSTAR profile)
EntrezGene (mouse)GeneID:378435
(SSTAR profile)
UniProt ID (human)MAFA_HUMAN
UniProt ID (mouse)MAFA_MOUSE
UniProt AC (human)Q8NHW3
(TFClass)
UniProt AC (mouse)Q8CF90
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
013255.252114.252384.252146.25
024243.751098.752003.752553.75
034394.0738.0882.03886.0
043927.01197.0831.03945.0
052609.01825.02237.03229.0
06357.02287.0123.07133.0
0778.0132.09648.042.0
08126.09671.056.047.0
0960.0200.073.09567.0
1096.031.09529.0244.0
119648.0107.038.0107.0
12145.07810.01173.0772.0
131979.01137.02838.03946.0
141611.04736.01311.02242.0
153842.01867.02494.01697.0
162231.01342.04599.01728.0
171518.54835.52154.51391.5
183701.02231.02426.01542.0
PFM
ACGT
010.3290.2140.2410.217
020.4290.1110.2020.258
030.4440.0750.0890.393
040.3970.1210.0840.398
050.2640.1840.2260.326
060.0360.2310.0120.721
070.0080.0130.9750.004
080.0130.9770.0060.005
090.0060.020.0070.966
100.010.0030.9630.025
110.9750.0110.0040.011
120.0150.7890.1180.078
130.20.1150.2870.399
140.1630.4780.1320.226
150.3880.1890.2520.171
160.2250.1360.4650.175
170.1530.4880.2180.141
180.3740.2250.2450.156
PWM
ACGT
010.274-0.157-0.037-0.142
020.539-0.811-0.2110.031
030.574-1.208-1.030.451
040.461-0.725-1.090.466
050.053-0.304-0.1010.266
06-1.931-0.079-2.9841.058
07-3.429-2.9151.36-4.024
08-2.9611.362-3.749-3.917
09-3.683-2.505-3.4931.351
10-3.227-4.3091.347-2.308
111.36-3.121-4.119-3.121
12-2.8221.149-0.746-1.163
13-0.223-0.7770.1370.466
14-0.4290.649-0.635-0.099
150.439-0.2820.008-0.377
16-0.104-0.6110.619-0.359
17-0.4880.669-0.139-0.575
180.402-0.104-0.02-0.473
Standard thresholds
P-value Threshold
0.001 3.79621
0.0005 4.87661
0.0001 7.18376