MAFA.H12CORE.1.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAFA.H12CORE.1.M.C
Gene (human)	MAFA (GeneCards)
Gene synonyms (human)
Gene (mouse)	Mafa
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	19
Consensus	ndWhnTGCTGACTCAGCdn
GC content	49.59%
Information content (bits; total / per base)	19.187 / 1.01
Data sources	Methyl-HT-SELEX
Aligned words	1055

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Mouse	1 (5)	0.724	0.748	0.648	0.65	0.695	0.742	2.255	2.329	77.509	100.337

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.997	0.996	0.987	0.982	0.922	0.917
Overall, 2 experiments	best	0.997	0.996	0.99	0.986	0.939	0.933
Methyl HT-SELEX, 1 experiments	median	0.997	0.996	0.984	0.979	0.905	0.901
Methyl HT-SELEX, 1 experiments	best	0.997	0.996	0.984	0.979	0.905	0.901
Non-Methyl HT-SELEX, 1 experiments	median	0.997	0.996	0.99	0.986	0.939	0.933
Non-Methyl HT-SELEX, 1 experiments	best	0.997	0.996	0.99	0.986	0.939	0.933

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.649	0.322	0.568	0.351

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Large MAF {1.1.3.1} (TFClass)
TFClass ID	TFClass: 1.1.3.1.2
HGNC	HGNC:23145
MGI	MGI:2673307
EntrezGene (human)	GeneID:389692 (SSTAR profile)
EntrezGene (mouse)	GeneID:378435 (SSTAR profile)
UniProt ID (human)	MAFA_HUMAN
UniProt ID (mouse)	MAFA_MOUSE
UniProt AC (human)	Q8NHW3 (TFClass)
UniProt AC (mouse)	Q8CF90 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	0 human, 1 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	MAFA.H12CORE.1.M.C.pcm
PWM	MAFA.H12CORE.1.M.C.pwm
PFM	MAFA.H12CORE.1.M.C.pfm
Alignment	MAFA.H12CORE.1.M.C.words.tsv
Threshold to P-value map	MAFA.H12CORE.1.M.C.thr
Motif in other formats
JASPAR format	MAFA.H12CORE.1.M.C_jaspar_format.txt
MEME format	MAFA.H12CORE.1.M.C_meme_format.meme
Transfac format	MAFA.H12CORE.1.M.C_transfac_format.txt
Homer format	MAFA.H12CORE.1.M.C_homer_format_0.001.txt MAFA.H12CORE.1.M.C_homer_format_0.0005.txt MAFA.H12CORE.1.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	348.5	217.5	265.5	223.5
02	487.25	115.25	210.25	242.25
03	514.0	66.0	75.0	400.0
04	482.0	116.0	55.0	402.0
05	288.0	186.0	214.0	367.0
06	19.0	227.0	4.0	805.0
07	1.0	0.0	1054.0	0.0
08	0.0	1055.0	0.0	0.0
09	0.0	0.0	0.0	1055.0
10	0.0	0.0	1055.0	0.0
11	1055.0	0.0	0.0	0.0
12	1.0	852.0	188.0	14.0
13	58.0	18.0	133.0	846.0
14	60.0	882.0	18.0	95.0
15	847.0	72.0	102.0	34.0
16	86.0	34.0	874.0	61.0
17	18.0	896.0	107.0	34.0
18	569.25	104.25	263.25	118.25
19	326.0	242.0	240.0	247.0

PFM

	A	C	G	T
01	0.33	0.206	0.252	0.212
02	0.462	0.109	0.199	0.23
03	0.487	0.063	0.071	0.379
04	0.457	0.11	0.052	0.381
05	0.273	0.176	0.203	0.348
06	0.018	0.215	0.004	0.763
07	0.001	0.0	0.999	0.0
08	0.0	1.0	0.0	0.0
09	0.0	0.0	0.0	1.0
10	0.0	0.0	1.0	0.0
11	1.0	0.0	0.0	0.0
12	0.001	0.808	0.178	0.013
13	0.055	0.017	0.126	0.802
14	0.057	0.836	0.017	0.09
15	0.803	0.068	0.097	0.032
16	0.082	0.032	0.828	0.058
17	0.017	0.849	0.101	0.032
18	0.54	0.099	0.25	0.112
19	0.309	0.229	0.227	0.234

PWM

	A	C	G	T
01	0.277	-0.191	0.007	-0.164
02	0.611	-0.819	-0.225	-0.084
03	0.664	-1.366	-1.241	0.414
04	0.6	-0.813	-1.543	0.419
05	0.087	-0.347	-0.208	0.329
06	-2.549	-0.149	-3.834	1.111
07	-4.574	-5.028	1.38	-5.028
08	-5.028	1.381	-5.028	-5.028
09	-5.028	-5.028	-5.028	1.381
10	-5.028	-5.028	1.381	-5.028
11	1.381	-5.028	-5.028	-5.028
12	-4.574	1.168	-0.336	-2.825
13	-1.492	-2.599	-0.678	1.161
14	-1.459	1.203	-2.599	-1.01
15	1.162	-1.281	-0.94	-2.005
16	-1.107	-2.005	1.193	-1.443
17	-2.599	1.218	-0.893	-2.005
18	0.766	-0.918	-0.002	-0.794
19	0.211	-0.085	-0.094	-0.065

Standard thresholds

P-value	Threshold
0.001	-0.26309
0.0005	1.34266
0.0001	4.70976