| Motif | MAF.H12RSNP.0.PM.A |
| Gene (human) | MAF (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Maf |
| Gene synonyms (mouse) | Maf2 |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | MAF.H12RSNP.0.PM.A |
| Gene (human) | MAF (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Maf |
| Gene synonyms (mouse) | Maf2 |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 19 |
| Consensus | vdWdnTGCTGAbdhddvhd |
| GC content | 46.18% |
| Information content (bits; total / per base) | 11.102 / 0.584 |
| Data sources | ChIP-Seq + Methyl-HT-SELEX |
| Aligned words | 500 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 5 (33) | 0.762 | 0.826 | 0.65 | 0.774 | 0.762 | 0.822 | 2.434 | 3.137 | 43.398 | 242.538 |
| Mouse | 4 (26) | 0.857 | 0.925 | 0.78 | 0.869 | 0.816 | 0.894 | 2.842 | 3.593 | 275.577 | 431.678 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.946 | 0.922 | 0.851 | 0.832 | 0.7 | 0.72 |
| best | 0.98 | 0.974 | 0.873 | 0.861 | 0.778 | 0.754 | |
| Methyl HT-SELEX, 2 experiments | median | 0.941 | 0.92 | 0.834 | 0.816 | 0.697 | 0.706 |
| best | 0.98 | 0.974 | 0.864 | 0.861 | 0.701 | 0.727 | |
| Non-Methyl HT-SELEX, 2 experiments | median | 0.946 | 0.922 | 0.856 | 0.832 | 0.738 | 0.733 |
| best | 0.958 | 0.945 | 0.873 | 0.836 | 0.778 | 0.754 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.924 | 0.31 | 0.914 | 0.582 |
| batch 2 | 0.708 | 0.421 | 0.739 | 0.532 |
| TF superclass | Basic domains {1} (TFClass) |
| TF class | Basic leucine zipper factors (bZIP) {1.1} (TFClass) |
| TF family | Maf-related {1.1.3} (TFClass) |
| TF subfamily | Large MAF {1.1.3.1} (TFClass) |
| TFClass ID | TFClass: 1.1.3.1.1 |
| HGNC | HGNC:6776 |
| MGI | MGI:96909 |
| EntrezGene (human) | GeneID:4094 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:17132 (SSTAR profile) |
| UniProt ID (human) | MAF_HUMAN |
| UniProt ID (mouse) | MAF_MOUSE |
| UniProt AC (human) | O75444 (TFClass) |
| UniProt AC (mouse) | P54843 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 5 human, 4 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 2 |
| PCM | MAF.H12RSNP.0.PM.A.pcm |
| PWM | MAF.H12RSNP.0.PM.A.pwm |
| PFM | MAF.H12RSNP.0.PM.A.pfm |
| Alignment | MAF.H12RSNP.0.PM.A.words.tsv |
| Threshold to P-value map | MAF.H12RSNP.0.PM.A.thr |
| Motif in other formats | |
| JASPAR format | MAF.H12RSNP.0.PM.A_jaspar_format.txt |
| MEME format | MAF.H12RSNP.0.PM.A_meme_format.meme |
| Transfac format | MAF.H12RSNP.0.PM.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 153.0 | 118.0 | 167.0 | 62.0 |
| 02 | 235.0 | 71.0 | 101.0 | 93.0 |
| 03 | 294.0 | 42.0 | 39.0 | 125.0 |
| 04 | 196.0 | 44.0 | 59.0 | 201.0 |
| 05 | 77.0 | 156.0 | 135.0 | 132.0 |
| 06 | 55.0 | 20.0 | 13.0 | 412.0 |
| 07 | 9.0 | 7.0 | 480.0 | 4.0 |
| 08 | 62.0 | 428.0 | 3.0 | 7.0 |
| 09 | 32.0 | 3.0 | 6.0 | 459.0 |
| 10 | 9.0 | 3.0 | 451.0 | 37.0 |
| 11 | 441.0 | 12.0 | 34.0 | 13.0 |
| 12 | 51.0 | 223.0 | 164.0 | 62.0 |
| 13 | 119.0 | 59.0 | 77.0 | 245.0 |
| 14 | 121.0 | 206.0 | 60.0 | 113.0 |
| 15 | 237.0 | 56.0 | 77.0 | 130.0 |
| 16 | 97.0 | 36.0 | 288.0 | 79.0 |
| 17 | 80.0 | 256.0 | 109.0 | 55.0 |
| 18 | 231.0 | 118.0 | 73.0 | 78.0 |
| 19 | 201.0 | 76.0 | 117.0 | 106.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.306 | 0.236 | 0.334 | 0.124 |
| 02 | 0.47 | 0.142 | 0.202 | 0.186 |
| 03 | 0.588 | 0.084 | 0.078 | 0.25 |
| 04 | 0.392 | 0.088 | 0.118 | 0.402 |
| 05 | 0.154 | 0.312 | 0.27 | 0.264 |
| 06 | 0.11 | 0.04 | 0.026 | 0.824 |
| 07 | 0.018 | 0.014 | 0.96 | 0.008 |
| 08 | 0.124 | 0.856 | 0.006 | 0.014 |
| 09 | 0.064 | 0.006 | 0.012 | 0.918 |
| 10 | 0.018 | 0.006 | 0.902 | 0.074 |
| 11 | 0.882 | 0.024 | 0.068 | 0.026 |
| 12 | 0.102 | 0.446 | 0.328 | 0.124 |
| 13 | 0.238 | 0.118 | 0.154 | 0.49 |
| 14 | 0.242 | 0.412 | 0.12 | 0.226 |
| 15 | 0.474 | 0.112 | 0.154 | 0.26 |
| 16 | 0.194 | 0.072 | 0.576 | 0.158 |
| 17 | 0.16 | 0.512 | 0.218 | 0.11 |
| 18 | 0.462 | 0.236 | 0.146 | 0.156 |
| 19 | 0.402 | 0.152 | 0.234 | 0.212 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.2 | -0.057 | 0.287 | -0.689 |
| 02 | 0.626 | -0.556 | -0.21 | -0.291 |
| 03 | 0.848 | -1.067 | -1.138 | 0.0 |
| 04 | 0.445 | -1.022 | -0.737 | 0.47 |
| 05 | -0.477 | 0.219 | 0.076 | 0.054 |
| 06 | -0.805 | -1.77 | -2.163 | 1.184 |
| 07 | -2.484 | -2.694 | 1.336 | -3.126 |
| 08 | -0.689 | 1.222 | -3.325 | -2.694 |
| 09 | -1.328 | -3.325 | -2.819 | 1.292 |
| 10 | -2.484 | -3.325 | 1.274 | -1.189 |
| 11 | 1.252 | -2.234 | -1.27 | -2.163 |
| 12 | -0.879 | 0.573 | 0.269 | -0.689 |
| 13 | -0.049 | -0.737 | -0.477 | 0.667 |
| 14 | -0.032 | 0.495 | -0.721 | -0.1 |
| 15 | 0.634 | -0.788 | -0.477 | 0.039 |
| 16 | -0.25 | -1.215 | 0.828 | -0.452 |
| 17 | -0.439 | 0.711 | -0.135 | -0.805 |
| 18 | 0.608 | -0.057 | -0.529 | -0.464 |
| 19 | 0.47 | -0.49 | -0.065 | -0.163 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.50161 |
| 0.0005 | 5.37761 |
| 0.0001 | 7.19141 |