MotifMAF.H12INVIVO.0.PM.A
Gene (human)MAF
(GeneCards)
Gene synonyms (human)
Gene (mouse)Maf
Gene synonyms (mouse)Maf2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length18
ConsensusnvdddnTGCTGAbdhhRb
GC content47.37%
Information content (bits; total / per base)11.303 / 0.628
Data sourcesChIP-Seq + Methyl-HT-SELEX
Aligned words1007

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (33) 0.782 0.839 0.692 0.794 0.771 0.823 2.473 3.138 48.284 244.886
Mouse 4 (26) 0.86 0.925 0.785 0.869 0.818 0.892 2.872 3.542 273.128 421.229

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.94 0.915 0.838 0.818 0.697 0.71
best 0.979 0.973 0.863 0.856 0.763 0.742
Methyl HT-SELEX, 2 experiments median 0.947 0.927 0.837 0.822 0.697 0.709
best 0.979 0.973 0.858 0.856 0.699 0.723
Non-Methyl HT-SELEX, 2 experiments median 0.94 0.915 0.841 0.818 0.722 0.72
best 0.949 0.934 0.863 0.827 0.763 0.742

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.936 0.302 0.928 0.556
batch 2 0.705 0.43 0.716 0.509
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyMaf-related {1.1.3} (TFClass)
TF subfamilyLarge MAF {1.1.3.1} (TFClass)
TFClass IDTFClass: 1.1.3.1.1
HGNCHGNC:6776
MGIMGI:96909
EntrezGene (human)GeneID:4094
(SSTAR profile)
EntrezGene (mouse)GeneID:17132
(SSTAR profile)
UniProt ID (human)MAF_HUMAN
UniProt ID (mouse)MAF_MOUSE
UniProt AC (human)O75444
(TFClass)
UniProt AC (mouse)P54843
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 4 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01303.0197.0285.0222.0
02341.0199.0327.0140.0
03485.0115.0219.0188.0
04541.084.0107.0275.0
05364.0102.0125.0416.0
06149.0278.0281.0299.0
0799.047.032.0829.0
0816.021.0960.010.0
09101.0876.09.021.0
1034.03.03.0967.0
1113.012.0931.051.0
12902.028.037.040.0
1365.0488.0310.0144.0
14229.0116.0128.0534.0
15213.0485.0116.0193.0
16508.0149.0144.0206.0
17202.050.0579.0176.0
18127.0507.0237.0136.0
PFM
ACGT
010.3010.1960.2830.22
020.3390.1980.3250.139
030.4820.1140.2170.187
040.5370.0830.1060.273
050.3610.1010.1240.413
060.1480.2760.2790.297
070.0980.0470.0320.823
080.0160.0210.9530.01
090.10.870.0090.021
100.0340.0030.0030.96
110.0130.0120.9250.051
120.8960.0280.0370.04
130.0650.4850.3080.143
140.2270.1150.1270.53
150.2120.4820.1150.192
160.5040.1480.1430.205
170.2010.050.5750.175
180.1260.5030.2350.135
PWM
ACGT
010.184-0.2430.123-0.125
020.302-0.2330.26-0.581
030.652-0.775-0.138-0.29
040.761-1.084-0.8460.088
050.367-0.894-0.6930.5
06-0.520.0990.1090.171
07-0.923-1.649-2.0171.187
08-2.66-2.4121.333-3.073
09-0.9031.242-3.162-2.412
10-1.959-3.982-3.9821.341
11-2.845-2.9161.303-1.57
121.271-2.143-1.879-1.804
13-1.3350.6590.207-0.554
14-0.094-0.767-0.670.748
15-0.1660.652-0.767-0.264
160.699-0.52-0.554-0.199
17-0.218-1.5890.829-0.355
18-0.6780.697-0.06-0.61
Standard thresholds
P-value Threshold
0.001 4.40986
0.0005 5.31656
0.0001 7.19261