MAF.H12INVITRO.1.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	MAF.H12INVITRO.1.PSM.A
Gene (human)	MAF (GeneCards)
Gene synonyms (human)
Gene (mouse)	Maf
Gene synonyms (mouse)	Maf2
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	A

Motif length	9
Consensus	nYGCTGAYd
GC content	54.79%
Information content (bits; total / per base)	10.44 / 1.16
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9631

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	5 (33)	0.762	0.811	0.644	0.709	0.712	0.766	1.927	2.137	41.06	176.444
Mouse	4 (26)	0.8	0.852	0.678	0.723	0.753	0.815	2.096	2.368	207.484	310.638

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.942	0.913	0.858	0.831	0.718	0.721
Overall, 4 experiments	best	0.964	0.936	0.888	0.866	0.785	0.764
Methyl HT-SELEX, 2 experiments	median	0.94	0.906	0.855	0.828	0.718	0.72
Methyl HT-SELEX, 2 experiments	best	0.964	0.936	0.888	0.866	0.73	0.741
Non-Methyl HT-SELEX, 2 experiments	median	0.942	0.913	0.858	0.831	0.738	0.732
Non-Methyl HT-SELEX, 2 experiments	best	0.944	0.915	0.888	0.852	0.785	0.764

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 1	0.899	0.465	0.889	0.533
batch 2	0.678	0.367	0.685	0.466

TF superclass	Basic domains {1} (TFClass)
TF class	Basic leucine zipper factors (bZIP) {1.1} (TFClass)
TF family	Maf-related {1.1.3} (TFClass)
TF subfamily	Large MAF {1.1.3.1} (TFClass)
TFClass ID	TFClass: 1.1.3.1.1
HGNC	HGNC:6776
MGI	MGI:96909
EntrezGene (human)	GeneID:4094 (SSTAR profile)
EntrezGene (mouse)	GeneID:17132 (SSTAR profile)
UniProt ID (human)	MAF_HUMAN
UniProt ID (mouse)	MAF_MOUSE
UniProt AC (human)	O75444 (TFClass)
UniProt AC (mouse)	P54843 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	5 human, 4 mouse
HT-SELEX	2
Methyl-HT-SELEX	2

PCM	MAF.H12INVITRO.1.PSM.A.pcm
PWM	MAF.H12INVITRO.1.PSM.A.pwm
PFM	MAF.H12INVITRO.1.PSM.A.pfm
Alignment	MAF.H12INVITRO.1.PSM.A.words.tsv
Threshold to P-value map	MAF.H12INVITRO.1.PSM.A.thr
Motif in other formats
JASPAR format	MAF.H12INVITRO.1.PSM.A_jaspar_format.txt
MEME format	MAF.H12INVITRO.1.PSM.A_meme_format.meme
Transfac format	MAF.H12INVITRO.1.PSM.A_transfac_format.txt
Homer format	MAF.H12INVITRO.1.PSM.A_homer_format_0.001.txt MAF.H12INVITRO.1.PSM.A_homer_format_0.0005.txt MAF.H12INVITRO.1.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2640.5	1985.5	1991.5	3013.5
02	674.0	1840.0	266.0	6851.0
03	72.0	356.0	9164.0	39.0
04	224.0	9370.0	21.0	16.0
05	13.0	28.0	34.0	9556.0
06	63.0	1.0	8987.0	580.0
07	9491.0	71.0	24.0	45.0
08	409.25	6636.25	1151.25	1434.25
09	1941.0	1601.0	3964.0	2125.0

PFM

	A	C	G	T
01	0.274	0.206	0.207	0.313
02	0.07	0.191	0.028	0.711
03	0.007	0.037	0.952	0.004
04	0.023	0.973	0.002	0.002
05	0.001	0.003	0.004	0.992
06	0.007	0.0	0.933	0.06
07	0.985	0.007	0.002	0.005
08	0.042	0.689	0.12	0.149
09	0.202	0.166	0.412	0.221

PWM

	A	C	G	T
01	0.092	-0.193	-0.19	0.224
02	-1.271	-0.269	-2.195	1.045
03	-3.479	-1.906	1.336	-4.067
04	-2.366	1.358	-4.639	-4.881
05	-5.06	-4.376	-4.196	1.378
06	-3.609	-6.596	1.316	-1.42
07	1.371	-3.493	-4.518	-3.931
08	-1.767	1.013	-0.737	-0.517
09	-0.215	-0.408	0.498	-0.125

Standard thresholds

P-value	Threshold
0.001	4.450125
0.0005	5.680755
0.0001	7.556975