MotifMAF.H12INVITRO.0.PM.A
Gene (human)MAF
(GeneCards)
Gene synonyms (human)
Gene (mouse)Maf
Gene synonyms (mouse)Maf2
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length18
ConsensusnddddTGCTGASKYdKSn
GC content50.63%
Information content (bits; total / per base)15.689 / 0.872
Data sourcesChIP-Seq + Methyl-HT-SELEX
Aligned words1943

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (33) 0.768 0.825 0.687 0.78 0.76 0.81 2.51 3.101 45.921 263.0
Mouse 4 (26) 0.849 0.913 0.774 0.853 0.818 0.89 2.878 3.521 261.46 419.585

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.95 0.929 0.853 0.834 0.711 0.722
best 0.983 0.978 0.881 0.865 0.774 0.757
Methyl HT-SELEX, 2 experiments median 0.957 0.94 0.853 0.838 0.711 0.722
best 0.983 0.978 0.865 0.865 0.722 0.729
Non-Methyl HT-SELEX, 2 experiments median 0.95 0.929 0.855 0.834 0.73 0.73
best 0.957 0.944 0.881 0.847 0.774 0.757

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.924 0.466 0.924 0.592
batch 2 0.697 0.404 0.716 0.511
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyMaf-related {1.1.3} (TFClass)
TF subfamilyLarge MAF {1.1.3.1} (TFClass)
TFClass IDTFClass: 1.1.3.1.1
HGNCHGNC:6776
MGIMGI:96909
EntrezGene (human)GeneID:4094
(SSTAR profile)
EntrezGene (mouse)GeneID:17132
(SSTAR profile)
UniProt ID (human)MAF_HUMAN
UniProt ID (mouse)MAF_MOUSE
UniProt AC (human)O75444
(TFClass)
UniProt AC (mouse)P54843
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 4 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01669.25357.25574.25342.25
02822.5180.5451.5488.5
03837.0116.0238.0752.0
04783.0193.0218.0749.0
05594.0204.0484.0661.0
0648.0403.017.01475.0
071.05.01937.00.0
089.01932.00.02.0
090.04.02.01937.0
100.00.01936.07.0
111937.01.03.02.0
1233.01363.0476.071.0
13223.069.0378.01273.0
14268.01246.0132.0297.0
151058.0142.0489.0254.0
16193.0123.01379.0248.0
1797.51458.5267.5119.5
18656.75407.75521.75356.75
PFM
ACGT
010.3440.1840.2960.176
020.4230.0930.2320.251
030.4310.060.1220.387
040.4030.0990.1120.385
050.3060.1050.2490.34
060.0250.2070.0090.759
070.0010.0030.9970.0
080.0050.9940.00.001
090.00.0020.0010.997
100.00.00.9960.004
110.9970.0010.0020.001
120.0170.7010.2450.037
130.1150.0360.1950.655
140.1380.6410.0680.153
150.5450.0730.2520.131
160.0990.0630.710.128
170.050.7510.1380.062
180.3380.210.2690.184
PWM
ACGT
010.319-0.3060.167-0.349
020.525-0.983-0.0730.006
030.542-1.42-0.7090.436
040.476-0.917-0.7960.432
050.2-0.862-0.0040.307
06-2.28-0.186-3.2511.108
07-5.127-4.2591.38-5.551
08-3.8011.378-5.551-4.83
09-5.551-4.416-4.831.38
10-5.551-5.5511.38-4.004
111.38-5.127-4.602-4.83
12-2.6371.029-0.02-1.901
13-0.774-1.928-0.250.961
14-0.5920.94-1.293-0.489
150.776-1.2210.007-0.645
16-0.917-1.3621.041-0.669
17-1.5911.097-0.593-1.391
180.301-0.1740.071-0.307
Standard thresholds
P-value Threshold
0.001 1.79066
0.0005 3.23891
0.0001 6.29596