MotifMAF.H12CORE.1.PSM.A
Gene (human)MAF
(GeneCards)
Gene synonyms (human)
Gene (mouse)Maf
Gene synonyms (mouse)Maf2
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
A
Motif length13
ConsensusndhnTGCTGACdn
GC content52.62%
Information content (bits; total / per base)12.751 / 0.981
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words1706

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 5 (33) 0.737 0.782 0.643 0.723 0.721 0.782 2.173 2.393 45.387 194.959
Mouse 4 (26) 0.788 0.84 0.693 0.751 0.776 0.838 2.399 2.79 222.391 322.602

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.939 0.916 0.838 0.81 0.727 0.721
best 0.977 0.964 0.891 0.879 0.755 0.753
Methyl HT-SELEX, 2 experiments median 0.952 0.93 0.855 0.836 0.727 0.729
best 0.977 0.964 0.891 0.879 0.74 0.753
Non-Methyl HT-SELEX, 2 experiments median 0.939 0.916 0.828 0.808 0.714 0.712
best 0.94 0.922 0.857 0.827 0.755 0.739

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.928 0.625 0.899 0.573
batch 2 0.687 0.404 0.724 0.497
TF superclassBasic domains {1} (TFClass)
TF classBasic leucine zipper factors (bZIP) {1.1} (TFClass)
TF familyMaf-related {1.1.3} (TFClass)
TF subfamilyLarge MAF {1.1.3.1} (TFClass)
TFClass IDTFClass: 1.1.3.1.1
HGNCHGNC:6776
MGIMGI:96909
EntrezGene (human)GeneID:4094
(SSTAR profile)
EntrezGene (mouse)GeneID:17132
(SSTAR profile)
UniProt ID (human)MAF_HUMAN
UniProt ID (mouse)MAF_MOUSE
UniProt AC (human)O75444
(TFClass)
UniProt AC (mouse)P54843
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 5 human, 4 mouse
HT-SELEX 2
Methyl-HT-SELEX 2
PCM
ACGT
01512.75282.75497.75412.75
02610.25233.25310.25552.25
03584.0298.0222.0602.0
04486.0250.0468.0502.0
0530.0413.06.01257.0
060.00.01706.00.0
070.01706.00.00.0
080.00.00.01706.0
090.00.01706.00.0
101706.00.00.00.0
118.01419.0181.098.0
12296.75205.75748.75454.75
13319.75672.75342.75370.75
PFM
ACGT
010.3010.1660.2920.242
020.3580.1370.1820.324
030.3420.1750.130.353
040.2850.1470.2740.294
050.0180.2420.0040.737
060.00.01.00.0
070.01.00.00.0
080.00.00.01.0
090.00.01.00.0
101.00.00.00.0
110.0050.8320.1060.057
120.1740.1210.4390.267
130.1870.3940.2010.217
PWM
ACGT
010.183-0.4090.154-0.033
020.357-0.6-0.3170.257
030.313-0.357-0.6490.343
040.13-0.5310.0920.162
05-2.599-0.032-3.9981.078
06-5.439-5.4391.383-5.439
07-5.4391.383-5.439-5.439
08-5.439-5.439-5.4391.383
09-5.439-5.4391.383-5.439
101.383-5.439-5.439-5.439
11-3.7711.199-0.851-1.456
12-0.361-0.7240.5610.064
13-0.2870.454-0.218-0.139
Standard thresholds
P-value Threshold
0.001 2.44601
0.0005 3.88437
0.0001 7.65197