| Motif | LMX1B.H12CORE.2.S.B |
| Gene (human) | LMX1B (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Lmx1b |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 2 |
| Quality | B |
| Motif | LMX1B.H12CORE.2.S.B |
| Gene (human) | LMX1B (GeneCards) |
| Gene synonyms (human) | |
| Gene (mouse) | Lmx1b |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 2 |
| Quality | B |
| Motif length | 20 |
| Consensus | vvYTAATTARYhhhWWWddd |
| GC content | 20.88% |
| Information content (bits; total / per base) | 17.208 / 0.86 |
| Data sources | HT-SELEX |
| Aligned words | 2258 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mouse | 1 (6) | 0.687 | 0.719 | 0.521 | 0.601 | 0.648 | 0.652 | 1.76 | 1.774 | 30.585 | 42.921 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 8 experiments | median | 0.98 | 0.965 | 0.967 | 0.948 | 0.883 | 0.876 |
| best | 0.988 | 0.977 | 0.987 | 0.976 | 0.981 | 0.965 | |
| Methyl HT-SELEX, 2 experiments | median | 0.985 | 0.972 | 0.983 | 0.969 | 0.953 | 0.94 |
| best | 0.988 | 0.977 | 0.987 | 0.976 | 0.975 | 0.963 | |
| Non-Methyl HT-SELEX, 6 experiments | median | 0.974 | 0.956 | 0.945 | 0.922 | 0.811 | 0.814 |
| best | 0.984 | 0.971 | 0.984 | 0.969 | 0.981 | 0.965 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 1 | 0.947 | 0.695 | 0.899 | 0.541 |
| batch 2 | 0.732 | 0.524 | 0.758 | 0.567 |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HD-LIM {3.1.5} (TFClass) |
| TF subfamily | LMX {3.1.5.6} (TFClass) |
| TFClass ID | TFClass: 3.1.5.6.2 |
| HGNC | HGNC:6654 |
| MGI | MGI:1100513 |
| EntrezGene (human) | GeneID:4010 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:16917 (SSTAR profile) |
| UniProt ID (human) | LMX1B_HUMAN |
| UniProt ID (mouse) | LMX1B_MOUSE |
| UniProt AC (human) | O60663 (TFClass) |
| UniProt AC (mouse) | O88609 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 0 human, 1 mouse |
| HT-SELEX | 6 |
| Methyl-HT-SELEX | 2 |
| PCM | LMX1B.H12CORE.2.S.B.pcm |
| PWM | LMX1B.H12CORE.2.S.B.pwm |
| PFM | LMX1B.H12CORE.2.S.B.pfm |
| Alignment | LMX1B.H12CORE.2.S.B.words.tsv |
| Threshold to P-value map | LMX1B.H12CORE.2.S.B.thr |
| Motif in other formats | |
| JASPAR format | LMX1B.H12CORE.2.S.B_jaspar_format.txt |
| MEME format | LMX1B.H12CORE.2.S.B_meme_format.meme |
| Transfac format | LMX1B.H12CORE.2.S.B_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 614.5 | 867.5 | 408.5 | 367.5 |
| 02 | 748.75 | 855.75 | 388.75 | 264.75 |
| 03 | 46.0 | 927.0 | 266.0 | 1019.0 |
| 04 | 0.0 | 20.0 | 0.0 | 2238.0 |
| 05 | 2255.0 | 0.0 | 3.0 | 0.0 |
| 06 | 2258.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 2258.0 |
| 08 | 0.0 | 1.0 | 0.0 | 2257.0 |
| 09 | 2255.0 | 0.0 | 3.0 | 0.0 |
| 10 | 1502.0 | 194.0 | 553.0 | 9.0 |
| 11 | 96.0 | 480.0 | 282.0 | 1400.0 |
| 12 | 401.0 | 354.0 | 308.0 | 1195.0 |
| 13 | 1226.0 | 333.0 | 292.0 | 407.0 |
| 14 | 1006.0 | 317.0 | 199.0 | 736.0 |
| 15 | 507.0 | 245.0 | 139.0 | 1367.0 |
| 16 | 883.0 | 152.0 | 80.0 | 1143.0 |
| 17 | 1315.0 | 89.0 | 86.0 | 768.0 |
| 18 | 1091.0 | 121.0 | 215.0 | 831.0 |
| 19 | 691.5 | 148.5 | 388.5 | 1029.5 |
| 20 | 613.75 | 216.75 | 495.75 | 931.75 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.272 | 0.384 | 0.181 | 0.163 |
| 02 | 0.332 | 0.379 | 0.172 | 0.117 |
| 03 | 0.02 | 0.411 | 0.118 | 0.451 |
| 04 | 0.0 | 0.009 | 0.0 | 0.991 |
| 05 | 0.999 | 0.0 | 0.001 | 0.0 |
| 06 | 1.0 | 0.0 | 0.0 | 0.0 |
| 07 | 0.0 | 0.0 | 0.0 | 1.0 |
| 08 | 0.0 | 0.0 | 0.0 | 1.0 |
| 09 | 0.999 | 0.0 | 0.001 | 0.0 |
| 10 | 0.665 | 0.086 | 0.245 | 0.004 |
| 11 | 0.043 | 0.213 | 0.125 | 0.62 |
| 12 | 0.178 | 0.157 | 0.136 | 0.529 |
| 13 | 0.543 | 0.147 | 0.129 | 0.18 |
| 14 | 0.446 | 0.14 | 0.088 | 0.326 |
| 15 | 0.225 | 0.109 | 0.062 | 0.605 |
| 16 | 0.391 | 0.067 | 0.035 | 0.506 |
| 17 | 0.582 | 0.039 | 0.038 | 0.34 |
| 18 | 0.483 | 0.054 | 0.095 | 0.368 |
| 19 | 0.306 | 0.066 | 0.172 | 0.456 |
| 20 | 0.272 | 0.096 | 0.22 | 0.413 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.085 | 0.428 | -0.322 | -0.427 |
| 02 | 0.282 | 0.415 | -0.371 | -0.753 |
| 03 | -2.47 | 0.495 | -0.749 | 0.589 |
| 04 | -5.682 | -3.251 | -5.682 | 1.375 |
| 05 | 1.382 | -5.682 | -4.744 | -5.682 |
| 06 | 1.384 | -5.682 | -5.682 | -5.682 |
| 07 | -5.682 | -5.682 | -5.682 | 1.384 |
| 08 | -5.682 | -5.264 | -5.682 | 1.383 |
| 09 | 1.382 | -5.682 | -4.744 | -5.682 |
| 10 | 0.976 | -1.062 | -0.021 | -3.948 |
| 11 | -1.755 | -0.162 | -0.691 | 0.906 |
| 12 | -0.341 | -0.465 | -0.603 | 0.748 |
| 13 | 0.774 | -0.525 | -0.656 | -0.326 |
| 14 | 0.576 | -0.574 | -1.036 | 0.264 |
| 15 | -0.107 | -0.83 | -1.391 | 0.882 |
| 16 | 0.446 | -1.303 | -1.933 | 0.704 |
| 17 | 0.844 | -1.829 | -1.863 | 0.307 |
| 18 | 0.657 | -1.528 | -0.96 | 0.386 |
| 19 | 0.202 | -1.326 | -0.372 | 0.599 |
| 20 | 0.083 | -0.952 | -0.129 | 0.5 |
| P-value | Threshold |
|---|---|
| 0.001 | 0.00041 |
| 0.0005 | 1.66271 |
| 0.0001 | 5.15976 |