MotifLMX1B.H12CORE.0.P.C
Gene (human)LMX1B
(GeneCards)
Gene synonyms (human)
Gene (mouse)Lmx1b
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
C
Motif length8
ConsensusYAATdAAR
GC content15.1%
Information content (bits; total / per base)9.921 / 1.24
Data sourcesChIP-Seq
Aligned words1007

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 1 (6) 0.733 0.755 0.584 0.656 0.733 0.743 2.024 2.081 41.886 48.444

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.941 0.905 0.919 0.881 0.847 0.819
best 0.984 0.964 0.979 0.96 0.96 0.939
Methyl HT-SELEX, 2 experiments median 0.979 0.958 0.965 0.945 0.922 0.9
best 0.984 0.964 0.973 0.954 0.95 0.927
Non-Methyl HT-SELEX, 6 experiments median 0.904 0.85 0.872 0.816 0.778 0.748
best 0.975 0.954 0.979 0.96 0.96 0.939

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.851 0.256 0.882 0.592
batch 2 0.682 0.445 0.775 0.548
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLMX {3.1.5.6} (TFClass)
TFClass IDTFClass: 3.1.5.6.2
HGNCHGNC:6654
MGIMGI:1100513
EntrezGene (human)GeneID:4010
(SSTAR profile)
EntrezGene (mouse)GeneID:16917
(SSTAR profile)
UniProt ID (human)LMX1B_HUMAN
UniProt ID (mouse)LMX1B_MOUSE
UniProt AC (human)O60663
(TFClass)
UniProt AC (mouse)O88609
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 1 mouse
HT-SELEX 6
Methyl-HT-SELEX 2
PCM
ACGT
01141.0176.019.0671.0
02943.011.038.015.0
03985.09.06.07.0
049.255.2527.25965.25
05199.2539.25483.25285.25
06955.255.2540.256.25
07875.2519.25107.255.25
08745.2556.25174.2531.25
PFM
ACGT
010.140.1750.0190.666
020.9360.0110.0380.015
030.9780.0090.0060.007
040.0090.0050.0270.959
050.1980.0390.480.283
060.9490.0050.040.006
070.8690.0190.1070.005
080.740.0560.1730.031
PWM
ACGT
01-0.574-0.355-2.5040.976
021.316-2.991-1.853-2.718
031.359-3.162-3.49-3.369
04-3.139-3.592-2.1691.339
05-0.232-1.8220.6490.124
061.329-3.592-1.798-3.459
071.241-2.492-0.844-3.592
081.081-1.475-0.365-2.039
Standard thresholds
P-value Threshold
0.001 4.724845
0.0005 5.63559
0.0001 7.3974