MotifLHX9.H12INVIVO.1.M.B
Gene (human)LHX9
(GeneCards)
Gene synonyms (human)
Gene (mouse)Lhx9
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length12
ConsensusnvYTAAYGAKbn
GC content36.81%
Information content (bits; total / per base)11.441 / 0.953
Data sourcesMethyl-HT-SELEX
Aligned words911

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (5) 0.782 0.811 0.653 0.694 0.708 0.715 1.911 1.959 67.347 109.174

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 8 experiments median 0.931 0.896 0.857 0.828 0.751 0.743
best 0.975 0.958 0.963 0.941 0.93 0.904
Methyl HT-SELEX, 3 experiments median 0.97 0.95 0.949 0.923 0.877 0.856
best 0.975 0.958 0.963 0.941 0.93 0.904
Non-Methyl HT-SELEX, 5 experiments median 0.909 0.872 0.788 0.766 0.651 0.666
best 0.964 0.937 0.941 0.91 0.88 0.851

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.784 0.264 0.768 0.439
batch 2 0.619 0.441 0.487 0.33
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLHX2-like {3.1.5.3} (TFClass)
TFClass IDTFClass: 3.1.5.3.2
HGNCHGNC:14222
MGIMGI:1316721
EntrezGene (human)GeneID:56956
(SSTAR profile)
EntrezGene (mouse)GeneID:16876
(SSTAR profile)
UniProt ID (human)LHX9_HUMAN
UniProt ID (mouse)LHX9_MOUSE
UniProt AC (human)Q9NQ69
(TFClass)
UniProt AC (mouse)Q9WUH2
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 5
Methyl-HT-SELEX 3
PCM
ACGT
01316.0247.0166.0182.0
02358.094.0400.059.0
0342.0251.056.0562.0
040.01.05.0905.0
05909.00.02.00.0
06904.01.06.00.0
070.0497.06.0408.0
080.00.0542.0369.0
09887.03.021.00.0
1063.078.0621.0149.0
11105.5372.5259.5173.5
12220.25171.25224.25295.25
PFM
ACGT
010.3470.2710.1820.2
020.3930.1030.4390.065
030.0460.2760.0610.617
040.00.0010.0050.993
050.9980.00.0020.0
060.9920.0010.0070.0
070.00.5460.0070.448
080.00.00.5950.405
090.9740.0030.0230.0
100.0690.0860.6820.164
110.1160.4090.2850.19
120.2420.1880.2460.324
PWM
ACGT
010.3250.081-0.314-0.222
020.45-0.8740.56-1.33
03-1.6580.097-1.380.899
04-4.903-4.441-3.5331.374
051.379-4.903-4.126-4.903
061.373-4.441-3.394-4.903
07-4.9030.776-3.3940.58
08-4.903-4.9030.8630.48
091.354-3.887-2.313-4.903
10-1.266-1.0570.998-0.42
11-0.7610.4890.13-0.27
12-0.033-0.283-0.0150.258
Standard thresholds
P-value Threshold
0.001 3.997465
0.0005 5.41878
0.0001 7.646965