MotifLHX8.H12CORE.1.M.C
Gene (human)LHX8
(GeneCards)
Gene synonyms (human)
Gene (mouse)Lhx8
Gene synonyms (mouse)Lhx7
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length13
ConsensusnvCTMGTTARYbn
GC content42.7%
Information content (bits; total / per base)12.222 / 0.94
Data sourcesMethyl-HT-SELEX
Aligned words1951

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.941 0.9 0.925 0.881 0.877 0.839
best 0.985 0.975 0.974 0.959 0.948 0.928
Methyl HT-SELEX, 1 experiments median 0.985 0.975 0.974 0.959 0.948 0.928
best 0.985 0.975 0.974 0.959 0.948 0.928
Non-Methyl HT-SELEX, 3 experiments median 0.919 0.864 0.899 0.844 0.827 0.786
best 0.964 0.936 0.95 0.919 0.927 0.892

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.784 0.092 0.735 0.43
batch 2 0.57 0.222 0.321 0.258
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLHX6-like {3.1.5.5} (TFClass)
TFClass IDTFClass: 3.1.5.5.2
HGNCHGNC:28838
MGIMGI:1096343
EntrezGene (human)GeneID:431707
(SSTAR profile)
EntrezGene (mouse)GeneID:16875
(SSTAR profile)
UniProt ID (human)LHX8_HUMAN
UniProt ID (mouse)LHX8_MOUSE
UniProt AC (human)Q68G74
(TFClass)
UniProt AC (mouse)O35652
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01520.75487.75454.75487.75
02378.5612.5768.5191.5
03161.01606.0146.038.0
040.01.01.01949.0
05556.01296.099.00.0
06696.00.01255.00.0
070.00.00.01951.0
080.00.00.01951.0
091936.00.015.00.0
10970.0156.0775.050.0
1136.0844.0300.0771.0
12221.0412.0745.0573.0
13682.5424.5430.5413.5
PFM
ACGT
010.2670.250.2330.25
020.1940.3140.3940.098
030.0830.8230.0750.019
040.00.0010.0010.999
050.2850.6640.0510.0
060.3570.00.6430.0
070.00.00.01.0
080.00.00.01.0
090.9920.00.0080.0
100.4970.080.3970.026
110.0180.4330.1540.395
120.1130.2110.3820.294
130.350.2180.2210.212
PWM
ACGT
010.0650.0-0.070.0
02-0.2520.2270.453-0.929
03-1.1011.189-1.197-2.507
04-5.555-5.131-5.1311.382
050.130.975-1.58-5.555
060.354-5.5550.943-5.555
07-5.555-5.555-5.5551.383
08-5.555-5.555-5.5551.383
091.376-5.555-3.367-5.555
100.686-1.1320.462-2.244
11-2.5590.547-0.4840.456
12-0.787-0.1680.4220.161
130.335-0.138-0.124-0.164
Standard thresholds
P-value Threshold
0.001 3.258575
0.0005 4.945915
0.0001 7.56071