Motif | LHX8.H12CORE.1.M.C |
Gene (human) | LHX8 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Lhx8 |
Gene synonyms (mouse) | Lhx7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | C |
Motif | LHX8.H12CORE.1.M.C |
Gene (human) | LHX8 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Lhx8 |
Gene synonyms (mouse) | Lhx7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 1 |
Quality | C |
Motif length | 13 |
Consensus | nvCTMGTTARYbn |
GC content | 42.7% |
Information content (bits; total / per base) | 12.222 / 0.94 |
Data sources | Methyl-HT-SELEX |
Aligned words | 1951 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.941 | 0.9 | 0.925 | 0.881 | 0.877 | 0.839 |
best | 0.985 | 0.975 | 0.974 | 0.959 | 0.948 | 0.928 | |
Methyl HT-SELEX, 1 experiments | median | 0.985 | 0.975 | 0.974 | 0.959 | 0.948 | 0.928 |
best | 0.985 | 0.975 | 0.974 | 0.959 | 0.948 | 0.928 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.919 | 0.864 | 0.899 | 0.844 | 0.827 | 0.786 |
best | 0.964 | 0.936 | 0.95 | 0.919 | 0.927 | 0.892 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.784 | 0.092 | 0.735 | 0.43 |
batch 2 | 0.57 | 0.222 | 0.321 | 0.258 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HD-LIM {3.1.5} (TFClass) |
TF subfamily | LHX6-like {3.1.5.5} (TFClass) |
TFClass ID | TFClass: 3.1.5.5.2 |
HGNC | HGNC:28838 |
MGI | MGI:1096343 |
EntrezGene (human) | GeneID:431707 (SSTAR profile) |
EntrezGene (mouse) | GeneID:16875 (SSTAR profile) |
UniProt ID (human) | LHX8_HUMAN |
UniProt ID (mouse) | LHX8_MOUSE |
UniProt AC (human) | Q68G74 (TFClass) |
UniProt AC (mouse) | O35652 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | LHX8.H12CORE.1.M.C.pcm |
PWM | LHX8.H12CORE.1.M.C.pwm |
PFM | LHX8.H12CORE.1.M.C.pfm |
Alignment | LHX8.H12CORE.1.M.C.words.tsv |
Threshold to P-value map | LHX8.H12CORE.1.M.C.thr |
Motif in other formats | |
JASPAR format | LHX8.H12CORE.1.M.C_jaspar_format.txt |
MEME format | LHX8.H12CORE.1.M.C_meme_format.meme |
Transfac format | LHX8.H12CORE.1.M.C_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 520.75 | 487.75 | 454.75 | 487.75 |
02 | 378.5 | 612.5 | 768.5 | 191.5 |
03 | 161.0 | 1606.0 | 146.0 | 38.0 |
04 | 0.0 | 1.0 | 1.0 | 1949.0 |
05 | 556.0 | 1296.0 | 99.0 | 0.0 |
06 | 696.0 | 0.0 | 1255.0 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 1951.0 |
08 | 0.0 | 0.0 | 0.0 | 1951.0 |
09 | 1936.0 | 0.0 | 15.0 | 0.0 |
10 | 970.0 | 156.0 | 775.0 | 50.0 |
11 | 36.0 | 844.0 | 300.0 | 771.0 |
12 | 221.0 | 412.0 | 745.0 | 573.0 |
13 | 682.5 | 424.5 | 430.5 | 413.5 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.267 | 0.25 | 0.233 | 0.25 |
02 | 0.194 | 0.314 | 0.394 | 0.098 |
03 | 0.083 | 0.823 | 0.075 | 0.019 |
04 | 0.0 | 0.001 | 0.001 | 0.999 |
05 | 0.285 | 0.664 | 0.051 | 0.0 |
06 | 0.357 | 0.0 | 0.643 | 0.0 |
07 | 0.0 | 0.0 | 0.0 | 1.0 |
08 | 0.0 | 0.0 | 0.0 | 1.0 |
09 | 0.992 | 0.0 | 0.008 | 0.0 |
10 | 0.497 | 0.08 | 0.397 | 0.026 |
11 | 0.018 | 0.433 | 0.154 | 0.395 |
12 | 0.113 | 0.211 | 0.382 | 0.294 |
13 | 0.35 | 0.218 | 0.221 | 0.212 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.065 | 0.0 | -0.07 | 0.0 |
02 | -0.252 | 0.227 | 0.453 | -0.929 |
03 | -1.101 | 1.189 | -1.197 | -2.507 |
04 | -5.555 | -5.131 | -5.131 | 1.382 |
05 | 0.13 | 0.975 | -1.58 | -5.555 |
06 | 0.354 | -5.555 | 0.943 | -5.555 |
07 | -5.555 | -5.555 | -5.555 | 1.383 |
08 | -5.555 | -5.555 | -5.555 | 1.383 |
09 | 1.376 | -5.555 | -3.367 | -5.555 |
10 | 0.686 | -1.132 | 0.462 | -2.244 |
11 | -2.559 | 0.547 | -0.484 | 0.456 |
12 | -0.787 | -0.168 | 0.422 | 0.161 |
13 | 0.335 | -0.138 | -0.124 | -0.164 |
P-value | Threshold |
---|---|
0.001 | 3.258575 |
0.0005 | 4.945915 |
0.0001 | 7.56071 |