Motif | LHX8.H12CORE.0.S.B |
Gene (human) | LHX8 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Lhx8 |
Gene synonyms (mouse) | Lhx7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif | LHX8.H12CORE.0.S.B |
Gene (human) | LHX8 (GeneCards) |
Gene synonyms (human) | |
Gene (mouse) | Lhx8 |
Gene synonyms (mouse) | Lhx7 |
LOGO | |
LOGO (reverse complement) | |
Motif subtype | 0 |
Quality | B |
Motif length | 13 |
Consensus | nvRYTAATTASnn |
GC content | 34.95% |
Information content (bits; total / per base) | 12.834 / 0.987 |
Data sources | HT-SELEX |
Aligned words | 7700 |
HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
---|---|---|---|---|---|---|---|
Overall, 4 experiments | median | 0.981 | 0.969 | 0.971 | 0.955 | 0.924 | 0.908 |
best | 0.986 | 0.977 | 0.98 | 0.967 | 0.971 | 0.954 | |
Methyl HT-SELEX, 1 experiments | median | 0.978 | 0.962 | 0.968 | 0.948 | 0.938 | 0.914 |
best | 0.978 | 0.962 | 0.968 | 0.948 | 0.938 | 0.914 | |
Non-Methyl HT-SELEX, 3 experiments | median | 0.985 | 0.976 | 0.975 | 0.962 | 0.91 | 0.901 |
best | 0.986 | 0.977 | 0.98 | 0.967 | 0.971 | 0.954 |
rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
---|---|---|---|---|
batch 1 | 0.976 | 0.726 | 0.947 | 0.605 |
batch 2 | 0.655 | 0.503 | 0.59 | 0.611 |
TF superclass | Helix-turn-helix domains {3} (TFClass) |
TF class | Homeo domain factors {3.1} (TFClass) |
TF family | HD-LIM {3.1.5} (TFClass) |
TF subfamily | LHX6-like {3.1.5.5} (TFClass) |
TFClass ID | TFClass: 3.1.5.5.2 |
HGNC | HGNC:28838 |
MGI | MGI:1096343 |
EntrezGene (human) | GeneID:431707 (SSTAR profile) |
EntrezGene (mouse) | GeneID:16875 (SSTAR profile) |
UniProt ID (human) | LHX8_HUMAN |
UniProt ID (mouse) | LHX8_MOUSE |
UniProt AC (human) | Q68G74 (TFClass) |
UniProt AC (mouse) | O35652 (TFClass) |
GRECO-DB-TF | yes |
ChIP-Seq | 0 human, 0 mouse |
HT-SELEX | 3 |
Methyl-HT-SELEX | 1 |
PCM | LHX8.H12CORE.0.S.B.pcm |
PWM | LHX8.H12CORE.0.S.B.pwm |
PFM | LHX8.H12CORE.0.S.B.pfm |
Alignment | LHX8.H12CORE.0.S.B.words.tsv |
Threshold to P-value map | LHX8.H12CORE.0.S.B.thr |
Motif in other formats | |
JASPAR format | LHX8.H12CORE.0.S.B_jaspar_format.txt |
MEME format | LHX8.H12CORE.0.S.B_meme_format.meme |
Transfac format | LHX8.H12CORE.0.S.B_transfac_format.txt |
Homer format |
A | C | G | T | |
---|---|---|---|---|
01 | 1593.25 | 1581.25 | 1908.25 | 2617.25 |
02 | 1904.5 | 2734.5 | 2141.5 | 919.5 |
03 | 3295.0 | 1416.0 | 2926.0 | 63.0 |
04 | 24.0 | 4290.0 | 279.0 | 3107.0 |
05 | 0.0 | 0.0 | 0.0 | 7700.0 |
06 | 6766.0 | 0.0 | 934.0 | 0.0 |
07 | 7700.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 0.0 | 7700.0 |
09 | 0.0 | 0.0 | 0.0 | 7700.0 |
10 | 6491.0 | 1.0 | 1207.0 | 1.0 |
11 | 400.0 | 3595.0 | 3410.0 | 295.0 |
12 | 1353.5 | 2735.5 | 2146.5 | 1464.5 |
13 | 2082.5 | 2073.5 | 1608.5 | 1935.5 |
A | C | G | T | |
---|---|---|---|---|
01 | 0.207 | 0.205 | 0.248 | 0.34 |
02 | 0.247 | 0.355 | 0.278 | 0.119 |
03 | 0.428 | 0.184 | 0.38 | 0.008 |
04 | 0.003 | 0.557 | 0.036 | 0.404 |
05 | 0.0 | 0.0 | 0.0 | 1.0 |
06 | 0.879 | 0.0 | 0.121 | 0.0 |
07 | 1.0 | 0.0 | 0.0 | 0.0 |
08 | 0.0 | 0.0 | 0.0 | 1.0 |
09 | 0.0 | 0.0 | 0.0 | 1.0 |
10 | 0.843 | 0.0 | 0.157 | 0.0 |
11 | 0.052 | 0.467 | 0.443 | 0.038 |
12 | 0.176 | 0.355 | 0.279 | 0.19 |
13 | 0.27 | 0.269 | 0.209 | 0.251 |
A | C | G | T | |
---|---|---|---|---|
01 | -0.189 | -0.196 | -0.009 | 0.307 |
02 | -0.011 | 0.351 | 0.106 | -0.738 |
03 | 0.537 | -0.307 | 0.418 | -3.386 |
04 | -4.297 | 0.801 | -1.925 | 0.478 |
05 | -6.759 | -6.759 | -6.759 | 1.385 |
06 | 1.256 | -6.759 | -0.722 | -6.759 |
07 | 1.385 | -6.759 | -6.759 | -6.759 |
08 | -6.759 | -6.759 | -6.759 | 1.385 |
09 | -6.759 | -6.759 | -6.759 | 1.385 |
10 | 1.215 | -6.389 | -0.466 | -6.389 |
11 | -1.567 | 0.624 | 0.571 | -1.869 |
12 | -0.352 | 0.351 | 0.109 | -0.273 |
13 | 0.079 | 0.074 | -0.179 | 0.005 |
P-value | Threshold |
---|---|
0.001 | 1.51741 |
0.0005 | 3.58151 |
0.0001 | 7.595665 |