MotifLHX8.H12CORE.0.S.B
Gene (human)LHX8
(GeneCards)
Gene synonyms (human)
Gene (mouse)Lhx8
Gene synonyms (mouse)Lhx7
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length13
ConsensusnvRYTAATTASnn
GC content34.95%
Information content (bits; total / per base)12.834 / 0.987
Data sourcesHT-SELEX
Aligned words7700

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.981 0.969 0.971 0.955 0.924 0.908
best 0.986 0.977 0.98 0.967 0.971 0.954
Methyl HT-SELEX, 1 experiments median 0.978 0.962 0.968 0.948 0.938 0.914
best 0.978 0.962 0.968 0.948 0.938 0.914
Non-Methyl HT-SELEX, 3 experiments median 0.985 0.976 0.975 0.962 0.91 0.901
best 0.986 0.977 0.98 0.967 0.971 0.954

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.976 0.726 0.947 0.605
batch 2 0.655 0.503 0.59 0.611
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLHX6-like {3.1.5.5} (TFClass)
TFClass IDTFClass: 3.1.5.5.2
HGNCHGNC:28838
MGIMGI:1096343
EntrezGene (human)GeneID:431707
(SSTAR profile)
EntrezGene (mouse)GeneID:16875
(SSTAR profile)
UniProt ID (human)LHX8_HUMAN
UniProt ID (mouse)LHX8_MOUSE
UniProt AC (human)Q68G74
(TFClass)
UniProt AC (mouse)O35652
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
011593.251581.251908.252617.25
021904.52734.52141.5919.5
033295.01416.02926.063.0
0424.04290.0279.03107.0
050.00.00.07700.0
066766.00.0934.00.0
077700.00.00.00.0
080.00.00.07700.0
090.00.00.07700.0
106491.01.01207.01.0
11400.03595.03410.0295.0
121353.52735.52146.51464.5
132082.52073.51608.51935.5
PFM
ACGT
010.2070.2050.2480.34
020.2470.3550.2780.119
030.4280.1840.380.008
040.0030.5570.0360.404
050.00.00.01.0
060.8790.00.1210.0
071.00.00.00.0
080.00.00.01.0
090.00.00.01.0
100.8430.00.1570.0
110.0520.4670.4430.038
120.1760.3550.2790.19
130.270.2690.2090.251
PWM
ACGT
01-0.189-0.196-0.0090.307
02-0.0110.3510.106-0.738
030.537-0.3070.418-3.386
04-4.2970.801-1.9250.478
05-6.759-6.759-6.7591.385
061.256-6.759-0.722-6.759
071.385-6.759-6.759-6.759
08-6.759-6.759-6.7591.385
09-6.759-6.759-6.7591.385
101.215-6.389-0.466-6.389
11-1.5670.6240.571-1.869
12-0.3520.3510.109-0.273
130.0790.074-0.1790.005
Standard thresholds
P-value Threshold
0.001 1.51741
0.0005 3.58151
0.0001 7.595665