MotifLHX6.H12CORE.1.S.B
Gene (human)LHX6
(GeneCards)
Gene synonyms (human)LHX6.1
Gene (mouse)Lhx6
Gene synonyms (mouse)Lhx6.1
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
B
Motif length14
ConsensusnnvSTAATTARbbn
GC content40.71%
Information content (bits; total / per base)12.657 / 0.904
Data sourcesHT-SELEX
Aligned words8423

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (12) 0.841 0.889 0.7 0.754 0.75 0.834 1.99 2.449 118.876 158.174

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.818 0.805 0.775 0.77 0.75 0.746
best 0.991 0.984 0.986 0.976 0.978 0.966
Methyl HT-SELEX, 1 experiments median 0.989 0.982 0.982 0.971 0.966 0.951
best 0.989 0.982 0.982 0.971 0.966 0.951
Non-Methyl HT-SELEX, 3 experiments median 0.646 0.627 0.568 0.569 0.534 0.541
best 0.991 0.984 0.986 0.976 0.978 0.966

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.95 0.827 0.922 0.606
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLHX6-like {3.1.5.5} (TFClass)
TFClass IDTFClass: 3.1.5.5.1
HGNCHGNC:21735
MGIMGI:1306803
EntrezGene (human)GeneID:26468
(SSTAR profile)
EntrezGene (mouse)GeneID:16874
(SSTAR profile)
UniProt ID (human)LHX6_HUMAN
UniProt ID (mouse)LHX6_MOUSE
UniProt AC (human)Q9UPM6
(TFClass)
UniProt AC (mouse)Q9R1R0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012406.251813.252194.252009.25
022142.751719.752872.751687.75
031265.03129.02962.01067.0
0414.03907.04245.0257.0
050.01498.00.06925.0
068421.02.00.00.0
078423.00.00.00.0
080.00.00.08423.0
090.02639.00.05784.0
108423.00.00.00.0
112379.0647.05256.0141.0
1264.03692.01952.02715.0
131225.51863.53644.51689.5
142323.02184.01784.02132.0
PFM
ACGT
010.2860.2150.2610.239
020.2540.2040.3410.2
030.150.3710.3520.127
040.0020.4640.5040.031
050.00.1780.00.822
061.00.00.00.0
071.00.00.00.0
080.00.00.01.0
090.00.3130.00.687
101.00.00.00.0
110.2820.0770.6240.017
120.0080.4380.2320.322
130.1450.2210.4330.201
140.2760.2590.2120.253
PWM
ACGT
010.133-0.1490.041-0.047
020.017-0.2020.31-0.221
03-0.5090.3960.341-0.679
04-4.8650.6180.701-2.096
05-6.838-0.34-6.8381.19
061.385-6.204-6.838-6.838
071.385-6.838-6.838-6.838
08-6.838-6.838-6.8381.385
09-6.8380.226-6.8381.01
101.385-6.838-6.838-6.838
110.122-1.1780.914-2.689
12-3.460.561-0.0760.254
13-0.541-0.1220.548-0.22
140.0980.036-0.1660.012
Standard thresholds
P-value Threshold
0.001 1.29291
0.0005 3.634815
0.0001 7.752765