MotifLHX6.H12CORE.0.P.B
Gene (human)LHX6
(GeneCards)
Gene synonyms (human)LHX6.1
Gene (mouse)Lhx6
Gene synonyms (mouse)Lhx6.1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length10
ConsensusbYAATCARnn
GC content39.52%
Information content (bits; total / per base)10.195 / 1.02
Data sourcesChIP-Seq
Aligned words481

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 2 (12) 0.874 0.93 0.806 0.848 0.801 0.84 2.387 2.477 174.922 205.495

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.813 0.791 0.771 0.758 0.748 0.737
best 0.986 0.977 0.976 0.963 0.967 0.948
Methyl HT-SELEX, 1 experiments median 0.98 0.969 0.969 0.951 0.958 0.935
best 0.98 0.969 0.969 0.951 0.958 0.935
Non-Methyl HT-SELEX, 3 experiments median 0.645 0.613 0.572 0.565 0.537 0.54
best 0.986 0.977 0.976 0.963 0.967 0.948

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 1 0.927 0.763 0.907 0.599
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLHX6-like {3.1.5.5} (TFClass)
TFClass IDTFClass: 3.1.5.5.1
HGNCHGNC:21735
MGIMGI:1306803
EntrezGene (human)GeneID:26468
(SSTAR profile)
EntrezGene (mouse)GeneID:16874
(SSTAR profile)
UniProt ID (human)LHX6_HUMAN
UniProt ID (mouse)LHX6_MOUSE
UniProt AC (human)Q9UPM6
(TFClass)
UniProt AC (mouse)Q9R1R0
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 2 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
0123.0166.0174.0118.0
0217.0172.02.0290.0
03446.034.01.00.0
04472.02.00.07.0
050.01.00.0480.0
061.0407.042.031.0
07476.00.02.03.0
08131.044.0283.023.0
09103.0135.0142.0101.0
10109.0151.0143.078.0
PFM
ACGT
010.0480.3450.3620.245
020.0350.3580.0040.603
030.9270.0710.0020.0
040.9810.0040.00.015
050.00.0020.00.998
060.0020.8460.0870.064
070.990.00.0040.006
080.2720.0910.5880.048
090.2140.2810.2950.21
100.2270.3140.2970.162
PWM
ACGT
01-1.6020.3190.366-0.019
02-1.8820.354-3.5370.873
031.301-1.232-3.869-4.368
041.358-3.537-4.368-2.657
05-4.368-3.869-4.3681.375
06-3.8691.21-1.029-1.32
071.366-4.368-3.537-3.289
080.085-0.9840.849-1.602
09-0.1530.1140.164-0.172
10-0.0970.2250.171-0.426
Standard thresholds
P-value Threshold
0.001 4.82311
0.0005 5.872735
0.0001 7.81849