MotifLHX2.H12INVIVO.1.S.C
Gene (human)LHX2
(GeneCards)
Gene synonyms (human)LH2
Gene (mouse)Lhx2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length19
ConsensusnhhWWWdnvYTAATTAvnn
GC content26.26%
Information content (bits; total / per base)15.479 / 0.815
Data sourcesHT-SELEX
Aligned words2014

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.786 0.795 0.576 0.581 0.807 0.821 2.36 2.385 89.699 97.018
Mouse 9 (53) 0.851 0.922 0.677 0.822 0.777 0.883 2.558 3.172 126.222 203.678

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.769 0.746 0.64 0.643 0.569 0.584
best 0.867 0.849 0.693 0.704 0.592 0.619
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLHX2-like {3.1.5.3} (TFClass)
TFClass IDTFClass: 3.1.5.3.1
HGNCHGNC:6594
MGIMGI:96785
EntrezGene (human)GeneID:9355
(SSTAR profile)
EntrezGene (mouse)GeneID:16870
(SSTAR profile)
UniProt ID (human)LHX2_HUMAN
UniProt ID (mouse)LHX2_MOUSE
UniProt AC (human)P50458
(TFClass)
UniProt AC (mouse)Q9Z0S2
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 9 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01569.75461.75291.75690.75
02517.0492.0121.0884.0
031097.0314.0104.0499.0
041351.081.0121.0461.0
05553.059.0103.01299.0
06391.0110.0167.01346.0
071051.0161.0285.0517.0
08711.0439.0502.0362.0
09577.0387.0873.0177.0
1087.01193.0200.0534.0
110.02.00.02012.0
122010.04.00.00.0
132014.00.00.00.0
140.00.00.02014.0
151.01.020.01992.0
161697.01.0315.01.0
17607.0282.01031.094.0
18304.75565.75483.75659.75
19552.5387.5488.5585.5
PFM
ACGT
010.2830.2290.1450.343
020.2570.2440.060.439
030.5450.1560.0520.248
040.6710.040.060.229
050.2750.0290.0510.645
060.1940.0550.0830.668
070.5220.080.1420.257
080.3530.2180.2490.18
090.2860.1920.4330.088
100.0430.5920.0990.265
110.00.0010.00.999
120.9980.0020.00.0
131.00.00.00.0
140.00.00.01.0
150.00.00.010.989
160.8430.00.1560.0
170.3010.140.5120.047
180.1510.2810.240.328
190.2740.1920.2430.291
PWM
ACGT
010.123-0.086-0.5430.315
020.026-0.023-1.4140.561
030.777-0.47-1.563-0.009
040.985-1.808-1.414-0.088
050.093-2.116-1.5720.945
06-0.252-1.508-1.0960.981
070.734-1.132-0.5660.026
080.344-0.137-0.003-0.328
090.136-0.2620.549-1.039
10-1.7380.86-0.9180.059
11-5.582-4.864-5.5821.382
121.381-4.45-5.582-5.582
131.383-5.582-5.582-5.582
14-5.582-5.582-5.5821.383
15-5.16-5.16-3.1391.372
161.212-5.16-0.467-5.16
170.186-0.5770.715-1.662
18-0.50.116-0.040.269
190.093-0.261-0.030.15
Standard thresholds
P-value Threshold
0.001 1.46291
0.0005 2.97301
0.0001 6.32036