MotifLHX2.H12INVITRO.0.PS.A
Gene (human)LHX2
(GeneCards)
Gene synonyms (human)LH2
Gene (mouse)Lhx2
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length9
ConsensushTAATKRSn
GC content33.08%
Information content (bits; total / per base)8.076 / 0.897
Data sourcesChIP-Seq + HT-SELEX
Aligned words976

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.858 0.867 0.748 0.752 0.831 0.843 2.51 2.56 146.452 173.161
Mouse 9 (53) 0.89 0.976 0.792 0.951 0.828 0.929 2.561 3.421 179.678 356.051

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Non-Methyl HT-SELEX, 2 experiments median 0.768 0.737 0.653 0.646 0.576 0.587
best 0.866 0.838 0.711 0.709 0.604 0.624
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLHX2-like {3.1.5.3} (TFClass)
TFClass IDTFClass: 3.1.5.3.1
HGNCHGNC:6594
MGIMGI:96785
EntrezGene (human)GeneID:9355
(SSTAR profile)
EntrezGene (mouse)GeneID:16870
(SSTAR profile)
UniProt ID (human)LHX2_HUMAN
UniProt ID (mouse)LHX2_MOUSE
UniProt AC (human)P50458
(TFClass)
UniProt AC (mouse)Q9Z0S2
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 9 mouse
HT-SELEX 2
Methyl-HT-SELEX 0
PCM
ACGT
01155.0355.0108.0358.0
0264.011.015.0886.0
03806.050.096.024.0
04897.039.020.020.0
0511.023.017.0925.0
0620.00.0437.0519.0
07574.08.0365.029.0
08115.0176.0622.063.0
09181.0363.0201.0231.0
PFM
ACGT
010.1590.3640.1110.367
020.0660.0110.0150.908
030.8260.0510.0980.025
040.9190.040.020.02
050.0110.0240.0170.948
060.020.00.4480.532
070.5880.0080.3740.03
080.1180.180.6370.065
090.1850.3720.2060.237
PWM
ACGT
01-0.450.373-0.8060.381
02-1.319-2.961-2.6881.284
031.19-1.558-0.922-2.257
041.297-1.797-2.426-2.426
05-2.961-2.297-2.5751.327
06-2.426-4.9610.580.751
070.851-3.230.4-2.079
08-0.744-0.3240.932-1.334
09-0.2960.395-0.192-0.054
Standard thresholds
P-value Threshold
0.001 5.05378
0.0005 5.839385
0.0001 7.33507