| Motif | LHX2.H12CORE.0.PS.A |
| Gene (human) | LHX2 (GeneCards) |
| Gene synonyms (human) | LH2 |
| Gene (mouse) | Lhx2 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 0 |
| Quality | A |
| Motif | LHX2.H12CORE.0.PS.A |
| Gene (human) | LHX2 (GeneCards) |
| Gene synonyms (human) | LH2 |
| Gene (mouse) | Lhx2 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 0 |
| Quality | A |
| Motif length | 9 |
| Consensus | hTAATKRSn |
| GC content | 33.08% |
| Information content (bits; total / per base) | 8.076 / 0.897 |
| Data sources | ChIP-Seq + HT-SELEX |
| Aligned words | 976 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 1 (6) | 0.858 | 0.867 | 0.748 | 0.752 | 0.831 | 0.843 | 2.51 | 2.56 | 146.452 | 173.161 |
| Mouse | 9 (53) | 0.89 | 0.976 | 0.792 | 0.951 | 0.828 | 0.929 | 2.561 | 3.421 | 179.678 | 356.051 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Non-Methyl HT-SELEX, 2 experiments | median | 0.768 | 0.737 | 0.653 | 0.646 | 0.576 | 0.587 |
| best | 0.866 | 0.838 | 0.711 | 0.709 | 0.604 | 0.624 | |
| TF superclass | Helix-turn-helix domains {3} (TFClass) |
| TF class | Homeo domain factors {3.1} (TFClass) |
| TF family | HD-LIM {3.1.5} (TFClass) |
| TF subfamily | LHX2-like {3.1.5.3} (TFClass) |
| TFClass ID | TFClass: 3.1.5.3.1 |
| HGNC | HGNC:6594 |
| MGI | MGI:96785 |
| EntrezGene (human) | GeneID:9355 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:16870 (SSTAR profile) |
| UniProt ID (human) | LHX2_HUMAN |
| UniProt ID (mouse) | LHX2_MOUSE |
| UniProt AC (human) | P50458 (TFClass) |
| UniProt AC (mouse) | Q9Z0S2 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 9 mouse |
| HT-SELEX | 2 |
| Methyl-HT-SELEX | 0 |
| PCM | LHX2.H12CORE.0.PS.A.pcm |
| PWM | LHX2.H12CORE.0.PS.A.pwm |
| PFM | LHX2.H12CORE.0.PS.A.pfm |
| Alignment | LHX2.H12CORE.0.PS.A.words.tsv |
| Threshold to P-value map | LHX2.H12CORE.0.PS.A.thr |
| Motif in other formats | |
| JASPAR format | LHX2.H12CORE.0.PS.A_jaspar_format.txt |
| MEME format | LHX2.H12CORE.0.PS.A_meme_format.meme |
| Transfac format | LHX2.H12CORE.0.PS.A_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 155.0 | 355.0 | 108.0 | 358.0 |
| 02 | 64.0 | 11.0 | 15.0 | 886.0 |
| 03 | 806.0 | 50.0 | 96.0 | 24.0 |
| 04 | 897.0 | 39.0 | 20.0 | 20.0 |
| 05 | 11.0 | 23.0 | 17.0 | 925.0 |
| 06 | 20.0 | 0.0 | 437.0 | 519.0 |
| 07 | 574.0 | 8.0 | 365.0 | 29.0 |
| 08 | 115.0 | 176.0 | 622.0 | 63.0 |
| 09 | 181.0 | 363.0 | 201.0 | 231.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.159 | 0.364 | 0.111 | 0.367 |
| 02 | 0.066 | 0.011 | 0.015 | 0.908 |
| 03 | 0.826 | 0.051 | 0.098 | 0.025 |
| 04 | 0.919 | 0.04 | 0.02 | 0.02 |
| 05 | 0.011 | 0.024 | 0.017 | 0.948 |
| 06 | 0.02 | 0.0 | 0.448 | 0.532 |
| 07 | 0.588 | 0.008 | 0.374 | 0.03 |
| 08 | 0.118 | 0.18 | 0.637 | 0.065 |
| 09 | 0.185 | 0.372 | 0.206 | 0.237 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.45 | 0.373 | -0.806 | 0.381 |
| 02 | -1.319 | -2.961 | -2.688 | 1.284 |
| 03 | 1.19 | -1.558 | -0.922 | -2.257 |
| 04 | 1.297 | -1.797 | -2.426 | -2.426 |
| 05 | -2.961 | -2.297 | -2.575 | 1.327 |
| 06 | -2.426 | -4.961 | 0.58 | 0.751 |
| 07 | 0.851 | -3.23 | 0.4 | -2.079 |
| 08 | -0.744 | -0.324 | 0.932 | -1.334 |
| 09 | -0.296 | 0.395 | -0.192 | -0.054 |
| P-value | Threshold |
|---|---|
| 0.001 | 5.05378 |
| 0.0005 | 5.839385 |
| 0.0001 | 7.33507 |