MotifLHX1.H12INVIVO.0.S.D
Gene (human)LHX1
(GeneCards)
Gene synonyms (human)LIM-1, LIM1
Gene (mouse)Lhx1
Gene synonyms (mouse)Lim-1, Lim1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length11
ConsensusnvbTAATKRnn
GC content33.84%
Information content (bits; total / per base)9.44 / 0.858
Data sourcesHT-SELEX
Aligned words9612

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.863 0.801 0.817 0.759 0.752 0.707
best 0.899 0.846 0.852 0.799 0.781 0.739
Methyl HT-SELEX, 1 experiments median 0.826 0.755 0.783 0.718 0.723 0.675
best 0.826 0.755 0.783 0.718 0.723 0.675
Non-Methyl HT-SELEX, 1 experiments median 0.899 0.846 0.852 0.799 0.781 0.739
best 0.899 0.846 0.852 0.799 0.781 0.739
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyHD-LIM {3.1.5} (TFClass)
TF subfamilyLHX1-like {3.1.5.2} (TFClass)
TFClass IDTFClass: 3.1.5.2.1
HGNCHGNC:6593
MGIMGI:99783
EntrezGene (human)GeneID:3975
(SSTAR profile)
EntrezGene (mouse)GeneID:16869
(SSTAR profile)
UniProt ID (human)LHX1_HUMAN
UniProt ID (mouse)LHX1_MOUSE
UniProt AC (human)P48742
(TFClass)
UniProt AC (mouse)P63006
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012424.02872.02300.02016.0
022089.02881.03886.0756.0
03793.02508.02957.03354.0
040.096.00.09516.0
059612.00.00.00.0
069612.00.00.00.0
073.042.00.09567.0
08155.01498.01561.06398.0
094936.0606.03538.0532.0
101730.03384.02732.01766.0
112313.752229.752687.752380.75
PFM
ACGT
010.2520.2990.2390.21
020.2170.30.4040.079
030.0830.2610.3080.349
040.00.010.00.99
051.00.00.00.0
061.00.00.00.0
070.00.0040.00.995
080.0160.1560.1620.666
090.5140.0630.3680.055
100.180.3520.2840.184
110.2410.2320.280.248
PWM
ACGT
010.0090.178-0.044-0.175
02-0.140.1810.48-1.154
03-1.1070.0430.2070.333
04-6.956-3.197-6.9561.376
051.386-6.956-6.956-6.956
061.386-6.956-6.956-6.956
07-6.119-3.995-6.9561.381
08-2.727-0.472-0.4310.979
090.719-1.3750.387-1.504
10-0.3280.3420.128-0.308
11-0.038-0.0750.112-0.009
Standard thresholds
P-value Threshold
0.001 5.511095
0.0005 6.225525
0.0001 7.542285