MotifLBX2.H12INVIVO.1.S.D
Gene (human)LBX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Lbx2
Gene synonyms (mouse)Lbx2h
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
D
Motif length17
ConsensusnnvYTAATTARYdvnhn
GC content35.39%
Information content (bits; total / per base)14.402 / 0.847
Data sourcesHT-SELEX
Aligned words2484

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.965 0.948 0.902 0.884 0.779 0.78
best 0.995 0.993 0.99 0.985 0.972 0.963
Methyl HT-SELEX, 1 experiments median 0.654 0.635 0.581 0.577 0.543 0.547
best 0.654 0.635 0.581 0.577 0.543 0.547
Non-Methyl HT-SELEX, 3 experiments median 0.988 0.981 0.965 0.953 0.851 0.85
best 0.995 0.993 0.99 0.985 0.972 0.963
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyLBX {3.1.2.10} (TFClass)
TFClass IDTFClass: 3.1.2.10.2
HGNCHGNC:15525
MGIMGI:1342288
EntrezGene (human)GeneID:85474
(SSTAR profile)
EntrezGene (mouse)GeneID:16815
(SSTAR profile)
UniProt ID (human)LBX2_HUMAN
UniProt ID (mouse)LBX2_MOUSE
UniProt AC (human)Q6XYB7
(TFClass)
UniProt AC (mouse)Q9WUN8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01650.5661.5669.5502.5
02617.0793.0734.0340.0
03560.0991.0733.0200.0
0464.01878.0128.0414.0
053.0819.01.01661.0
062455.027.01.01.0
072477.00.07.00.0
080.00.00.02484.0
090.00.00.02484.0
102474.00.010.00.0
111807.080.0562.035.0
1226.01009.0191.01258.0
13315.0280.0659.01230.0
141494.0408.0345.0237.0
15680.0680.0699.0425.0
16434.75977.75425.75645.75
17668.75605.75569.75639.75
PFM
ACGT
010.2620.2660.270.202
020.2480.3190.2950.137
030.2250.3990.2950.081
040.0260.7560.0520.167
050.0010.330.00.669
060.9880.0110.00.0
070.9970.00.0030.0
080.00.00.01.0
090.00.00.01.0
100.9960.00.0040.0
110.7270.0320.2260.014
120.010.4060.0770.506
130.1270.1130.2650.495
140.6010.1640.1390.095
150.2740.2740.2810.171
160.1750.3940.1710.26
170.2690.2440.2290.258
PWM
ACGT
010.0460.0630.075-0.211
02-0.0060.2440.167-0.6
03-0.1030.4660.165-1.126
04-2.2461.105-1.567-0.404
05-4.8340.276-5.3510.982
061.372-3.069-5.351-5.351
071.381-5.764-4.242-5.764
08-5.764-5.764-5.7641.384
09-5.764-5.764-5.7641.384
101.38-5.764-3.953-5.764
111.066-2.028-0.099-2.825
12-3.1040.484-1.1720.704
13-0.676-0.7930.0590.682
140.876-0.418-0.585-0.958
150.090.090.118-0.378
16-0.3550.453-0.3760.039
170.074-0.025-0.0860.03
Standard thresholds
P-value Threshold
0.001 1.86316
0.0005 3.33211
0.0001 6.72741