MotifLBX2.H12INVITRO.2.M.C
Gene (human)LBX2
(GeneCards)
Gene synonyms (human)
Gene (mouse)Lbx2
Gene synonyms (mouse)Lbx2h
LOGO
LOGO (reverse complement)
Motif subtype2
Quality
C
Motif length14
ConsensusnbMTMATTAAYbnn
GC content32.71%
Information content (bits; total / per base)12.005 / 0.857
Data sourcesMethyl-HT-SELEX
Aligned words1842

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.938 0.912 0.878 0.849 0.768 0.759
best 0.991 0.987 0.982 0.973 0.959 0.945
Methyl HT-SELEX, 1 experiments median 0.681 0.654 0.612 0.596 0.57 0.564
best 0.681 0.654 0.612 0.596 0.57 0.564
Non-Methyl HT-SELEX, 3 experiments median 0.972 0.957 0.94 0.917 0.839 0.826
best 0.991 0.987 0.982 0.973 0.959 0.945
TF superclassHelix-turn-helix domains {3} (TFClass)
TF classHomeo domain factors {3.1} (TFClass)
TF familyNK-related {3.1.2} (TFClass)
TF subfamilyLBX {3.1.2.10} (TFClass)
TFClass IDTFClass: 3.1.2.10.2
HGNCHGNC:15525
MGIMGI:1342288
EntrezGene (human)GeneID:85474
(SSTAR profile)
EntrezGene (mouse)GeneID:16815
(SSTAR profile)
UniProt ID (human)LBX2_HUMAN
UniProt ID (mouse)LBX2_MOUSE
UniProt AC (human)Q6XYB7
(TFClass)
UniProt AC (mouse)Q9WUN8
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 0 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01525.0329.0547.0441.0
02263.25803.25498.25277.25
03278.01278.0128.0158.0
0427.0185.028.01602.0
051029.0804.01.08.0
061203.09.0630.00.0
071.01.00.01840.0
080.03.00.01839.0
091823.03.016.00.0
101464.092.0234.052.0
1131.0535.0247.01029.0
12231.0292.0467.0852.0
13950.75296.75296.75297.75
14565.75370.75339.75565.75
PFM
ACGT
010.2850.1790.2970.239
020.1430.4360.270.151
030.1510.6940.0690.086
040.0150.10.0150.87
050.5590.4360.0010.004
060.6530.0050.3420.0
070.0010.0010.00.999
080.00.0020.00.998
090.990.0020.0090.0
100.7950.050.1270.028
110.0170.290.1340.559
120.1250.1590.2540.463
130.5160.1610.1610.162
140.3070.2010.1840.307
PWM
ACGT
010.131-0.3350.171-0.043
02-0.5560.5550.078-0.505
03-0.5021.018-1.27-1.062
04-2.773-0.906-2.7391.244
050.8020.556-5.079-3.846
060.958-3.7490.312-5.505
07-5.079-5.079-5.5051.382
08-5.505-4.551-5.5051.382
091.373-4.551-3.253-5.505
101.154-1.594-0.673-2.15
11-2.6440.149-0.6190.802
12-0.686-0.4530.0140.613
130.723-0.437-0.437-0.434
140.205-0.216-0.3030.205
Standard thresholds
P-value Threshold
0.001 3.96421
0.0005 5.19251
0.0001 7.43371