MotifKMT2B.H12INVIVO.0.P.B
Gene (human)KMT2B
(GeneCards)
Gene synonyms (human)HRX2, KIAA0304, MLL2, MLL4, TRX2, WBP7
Gene (mouse)Kmt2b
Gene synonyms (mouse)Mll2, Trx2, Wbp7
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
B
Motif length8
ConsensusGCGGCGGC
GC content96.36%
Information content (bits; total / per base)13.976 / 1.747
Data sourcesChIP-Seq
Aligned words998

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Mouse 15 (102) 0.811 0.878 0.608 0.733 0.593 0.729 1.174 1.505 8.097 26.699
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classCXXC zinc finger factors {2.6} (TFClass)
TF familyCpG-binding {2.6.1} (TFClass)
TF subfamily {2.6.1.0} (TFClass)
TFClass IDTFClass: 2.6.1.0.7
HGNCHGNC:15840
MGIMGI:109565
EntrezGene (human)GeneID:9757
(SSTAR profile)
EntrezGene (mouse)GeneID:75410
(SSTAR profile)
UniProt ID (human)KMT2B_HUMAN
UniProt ID (mouse)KMT2B_MOUSE
UniProt AC (human)Q9UMN6
(TFClass)
UniProt AC (mouse)O08550
(TFClass)
GRECO-DB-TF
no
ChIP-Seq 0 human, 15 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
012.00.0984.012.0
0243.0950.00.05.0
037.01.0938.052.0
044.03.0987.04.0
0529.0957.01.011.0
0617.04.0897.080.0
074.04.0987.03.0
0814.0976.04.04.0
PFM
ACGT
010.0020.00.9860.012
020.0430.9520.00.005
030.0070.0010.940.052
040.0040.0030.9890.004
050.0290.9590.0010.011
060.0170.0040.8990.08
070.0040.0040.9890.003
080.0140.9780.0040.004
PWM
ACGT
01-4.211-4.981.367-2.907
02-1.7261.332-4.98-3.62
03-3.36-4.5231.319-1.542
04-3.781-3.9731.37-3.781
05-2.1011.339-4.523-2.983
06-2.596-3.7811.275-1.123
07-3.781-3.7811.37-3.973
08-2.7711.359-3.781-3.781
Standard thresholds
P-value Threshold
0.001 2.67379
0.0005 4.0455
0.0001 6.54965