MotifKMT2A.H12INVITRO.0.P.D
Gene (human)KMT2A
(GeneCards)
Gene synonyms (human)ALL1, CXXC7, HRX, HTRX, MLL, MLL1, TRX1
Gene (mouse)Kmt2a
Gene synonyms (mouse)All1, Hrx, Mll, Mll1
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
D
Motif length23
ConsensusCSSvGCYSSSSCYSCSGCYbCSb
GC content86.92%
Information content (bits; total / per base)18.946 / 0.824
Data sourcesChIP-Seq
Aligned words995

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 36 (223) 0.713 0.83 0.481 0.645 0.658 0.892 2.617 4.379 2.108 16.658
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classCXXC zinc finger factors {2.6} (TFClass)
TF familyCpG-binding {2.6.1} (TFClass)
TF subfamily {2.6.1.0} (TFClass)
TFClass IDTFClass: 2.6.1.0.4
HGNCHGNC:7132
MGIMGI:96995
EntrezGene (human)GeneID:4297
(SSTAR profile)
EntrezGene (mouse)
UniProt ID (human)KMT2A_HUMAN
UniProt ID (mouse)KMT2A_MOUSE
UniProt AC (human)Q03164
(TFClass)
UniProt AC (mouse)P55200
(TFClass)
GRECO-DB-TF
no
ChIP-Seq 36 human, 0 mouse
HT-SELEX 0
Methyl-HT-SELEX 0
PCM
ACGT
0124.0796.0112.063.0
0256.0501.0342.096.0
0340.0621.0300.034.0
04112.0534.0257.092.0
0533.032.0831.099.0
0617.0827.079.072.0
0729.0656.094.0216.0
0827.0358.0535.075.0
0923.0786.0113.073.0
1056.0598.0270.071.0
1135.0189.0723.048.0
126.0813.0109.067.0
1335.0781.085.094.0
1445.0161.0692.097.0
1527.0886.052.030.0
1697.0700.0101.097.0
1718.095.0795.087.0
1810.0892.049.044.0
1941.0752.049.0153.0
2035.0167.0533.0260.0
2117.0850.0101.027.0
2227.0722.0164.082.0
2387.0434.0355.0119.0
PFM
ACGT
010.0240.80.1130.063
020.0560.5040.3440.096
030.040.6240.3020.034
040.1130.5370.2580.092
050.0330.0320.8350.099
060.0170.8310.0790.072
070.0290.6590.0940.217
080.0270.360.5380.075
090.0230.790.1140.073
100.0560.6010.2710.071
110.0350.190.7270.048
120.0060.8170.110.067
130.0350.7850.0850.094
140.0450.1620.6950.097
150.0270.890.0520.03
160.0970.7040.1020.097
170.0180.0950.7990.087
180.010.8960.0490.044
190.0410.7560.0490.154
200.0350.1680.5360.261
210.0170.8540.1020.027
220.0270.7260.1650.082
230.0870.4360.3570.12
PWM
ACGT
01-2.2761.158-0.79-1.353
02-1.4680.6970.316-0.941
03-1.7920.9110.186-1.947
04-0.790.760.032-0.983
05-1.976-2.0051.201-0.911
06-2.5931.197-1.132-1.223
07-2.0980.965-0.962-0.14
08-2.1660.3620.762-1.183
09-2.3161.146-0.781-1.21
10-1.4680.8730.081-1.237
11-1.92-0.2731.062-1.617
12-3.4791.179-0.816-1.293
13-1.921.139-1.061-0.962
14-1.679-0.4311.019-0.931
15-2.1661.265-1.539-2.066
16-0.9311.03-0.891-0.931
17-2.541-0.9511.157-1.038
18-3.0621.272-1.597-1.701
19-1.7691.102-1.597-0.482
20-1.92-0.3950.7580.044
21-2.5931.224-0.891-2.166
22-2.1661.061-0.413-1.096
23-1.0380.5540.354-0.73
Standard thresholds
P-value Threshold
0.001 2.09521
0.0005 3.24486
0.0001 5.70421