KLF5.H12RSNP.0.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF5.H12RSNP.0.PM.A
Gene (human)	KLF5 (GeneCards)
Gene synonyms (human)	BTEB2, CKLF, IKLF
Gene (mouse)	Klf5
Gene synonyms (mouse)	Bteb2, Iklf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	dnnWGGGYGKGRY
GC content	64.81%
Information content (bits; total / per base)	10.785 / 0.83
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	14 (86)	0.818	0.888	0.686	0.78	0.844	0.917	2.978	3.521	80.471	212.509
Mouse	7 (47)	0.824	0.855	0.696	0.748	0.822	0.874	2.756	3.202	65.678	158.921

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.819	0.77	0.697	0.677	0.593	0.606
Methyl HT-SELEX, 1 experiments	best	0.819	0.77	0.697	0.677	0.593	0.606

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	3.049	2.911	0.15	0.064

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.5
HGNC	HGNC:6349
MGI	MGI:1338056
EntrezGene (human)	GeneID:688 (SSTAR profile)
EntrezGene (mouse)	GeneID:12224 (SSTAR profile)
UniProt ID (human)	KLF5_HUMAN
UniProt ID (mouse)	KLF5_MOUSE
UniProt AC (human)	Q13887 (TFClass)
UniProt AC (mouse)	Q9Z0Z7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	14 human, 7 mouse
HT-SELEX	0
Methyl-HT-SELEX	1

PCM	KLF5.H12RSNP.0.PM.A.pcm
PWM	KLF5.H12RSNP.0.PM.A.pwm
PFM	KLF5.H12RSNP.0.PM.A.pfm
Alignment	KLF5.H12RSNP.0.PM.A.words.tsv
Threshold to P-value map	KLF5.H12RSNP.0.PM.A.thr
Motif in other formats
JASPAR format	KLF5.H12RSNP.0.PM.A_jaspar_format.txt
MEME format	KLF5.H12RSNP.0.PM.A_meme_format.meme
Transfac format	KLF5.H12RSNP.0.PM.A_transfac_format.txt
Homer format	KLF5.H12RSNP.0.PM.A_homer_format_0.001.txt KLF5.H12RSNP.0.PM.A_homer_format_0.0005.txt KLF5.H12RSNP.0.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	354.0	159.0	315.0	172.0
02	240.0	169.0	383.0	208.0
03	281.0	350.0	216.0	153.0
04	463.0	21.0	122.0	394.0
05	44.0	1.0	893.0	62.0
06	2.0	17.0	970.0	11.0
07	25.0	24.0	946.0	5.0
08	225.0	265.0	6.0	504.0
09	63.0	9.0	900.0	28.0
10	30.0	25.0	293.0	652.0
11	27.0	9.0	944.0	20.0
12	199.0	56.0	641.0	104.0
13	154.0	624.0	67.0	155.0

PFM

	A	C	G	T
01	0.354	0.159	0.315	0.172
02	0.24	0.169	0.383	0.208
03	0.281	0.35	0.216	0.153
04	0.463	0.021	0.122	0.394
05	0.044	0.001	0.893	0.062
06	0.002	0.017	0.97	0.011
07	0.025	0.024	0.946	0.005
08	0.225	0.265	0.006	0.504
09	0.063	0.009	0.9	0.028
10	0.03	0.025	0.293	0.652
11	0.027	0.009	0.944	0.02
12	0.199	0.056	0.641	0.104
13	0.154	0.624	0.067	0.155

PWM

	A	C	G	T
01	0.346	-0.449	0.23	-0.371
02	-0.041	-0.388	0.424	-0.183
03	0.116	0.335	-0.145	-0.487
04	0.613	-2.405	-0.71	0.452
05	-1.706	-4.525	1.268	-1.374
06	-4.213	-2.598	1.351	-2.985
07	-2.243	-2.281	1.326	-3.622
08	-0.105	0.058	-3.484	0.698
09	-1.358	-3.156	1.276	-2.136
10	-2.071	-2.243	0.158	0.954
11	-2.171	-3.156	1.324	-2.45
12	-0.226	-1.473	0.937	-0.867
13	-0.48	0.911	-1.298	-0.474

Standard thresholds

P-value	Threshold
0.001	4.52831
0.0005	5.43426
0.0001	7.33116