KLF5.H12CORE.0.PM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF5.H12CORE.0.PM.A
Gene (human)	KLF5 (GeneCards)
Gene synonyms (human)	BTEB2, CKLF, IKLF
Gene (mouse)	Klf5
Gene synonyms (mouse)	Bteb2, Iklf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	13
Consensus	nndGGGYGKGRYh
GC content	66.2%
Information content (bits; total / per base)	11.266 / 0.867
Data sources	ChIP-Seq + Methyl-HT-SELEX
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	14 (86)	0.842	0.909	0.718	0.82	0.852	0.929	3.007	3.592	97.867	235.678
Mouse	7 (47)	0.837	0.874	0.715	0.779	0.827	0.879	2.776	3.207	70.77	178.569

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.832	0.78	0.71	0.688	0.593	0.61
Methyl HT-SELEX, 1 experiments	best	0.832	0.78	0.71	0.688	0.593	0.61

rSNP benchmarking, ADASTRA	odds-ratio	-log-Fisher's P	Pearson r	Kendall tau
#	2.323	1.807	0.165	0.058

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.5
HGNC	HGNC:6349
MGI	MGI:1338056
EntrezGene (human)	GeneID:688 (SSTAR profile)
EntrezGene (mouse)	GeneID:12224 (SSTAR profile)
UniProt ID (human)	KLF5_HUMAN
UniProt ID (mouse)	KLF5_MOUSE
UniProt AC (human)	Q13887 (TFClass)
UniProt AC (mouse)	Q9Z0Z7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	14 human, 7 mouse
HT-SELEX	0
Methyl-HT-SELEX	1

PCM	KLF5.H12CORE.0.PM.A.pcm
PWM	KLF5.H12CORE.0.PM.A.pwm
PFM	KLF5.H12CORE.0.PM.A.pfm
Alignment	KLF5.H12CORE.0.PM.A.words.tsv
Threshold to P-value map	KLF5.H12CORE.0.PM.A.thr
Motif in other formats
JASPAR format	KLF5.H12CORE.0.PM.A_jaspar_format.txt
MEME format	KLF5.H12CORE.0.PM.A_meme_format.meme
Transfac format	KLF5.H12CORE.0.PM.A_transfac_format.txt
Homer format	KLF5.H12CORE.0.PM.A_homer_format_0.001.txt KLF5.H12CORE.0.PM.A_homer_format_0.0005.txt KLF5.H12CORE.0.PM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	259.0	199.0	342.0	198.0
02	262.0	329.0	205.0	202.0
03	415.0	33.0	189.0	361.0
04	73.0	1.0	906.0	18.0
05	3.0	4.0	987.0	4.0
06	6.0	8.0	983.0	1.0
07	156.0	303.0	3.0	536.0
08	21.0	8.0	958.0	11.0
09	21.0	25.0	317.0	635.0
10	41.0	16.0	912.0	29.0
11	221.0	62.0	588.0	127.0
12	90.0	663.0	92.0	153.0
13	250.0	353.0	103.0	292.0

PFM

	A	C	G	T
01	0.26	0.199	0.343	0.198
02	0.263	0.33	0.205	0.202
03	0.416	0.033	0.189	0.362
04	0.073	0.001	0.908	0.018
05	0.003	0.004	0.989	0.004
06	0.006	0.008	0.985	0.001
07	0.156	0.304	0.003	0.537
08	0.021	0.008	0.96	0.011
09	0.021	0.025	0.318	0.636
10	0.041	0.016	0.914	0.029
11	0.221	0.062	0.589	0.127
12	0.09	0.664	0.092	0.153
13	0.251	0.354	0.103	0.293

PWM

	A	C	G	T
01	0.037	-0.224	0.313	-0.229
02	0.049	0.275	-0.195	-0.21
03	0.506	-1.979	-0.276	0.367
04	-1.213	-4.523	1.285	-2.544
05	-3.973	-3.781	1.37	-3.781
06	-3.482	-3.252	1.366	-4.523
07	-0.465	0.193	-3.973	0.761
08	-2.403	-3.252	1.34	-2.983
09	-2.403	-2.241	0.238	0.93
10	-1.772	-2.651	1.291	-2.101
11	-0.12	-1.372	0.853	-0.669
12	-1.008	0.973	-0.986	-0.485
13	0.002	0.345	-0.875	0.156

Standard thresholds

P-value	Threshold
0.001	4.34111
0.0005	5.33151
0.0001	7.415375