MotifKLF3.H12INVITRO.1.M.C
Gene (human)KLF3
(GeneCards)
Gene synonyms (human)BKLF
Gene (mouse)Klf3
Gene synonyms (mouse)Bklf
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length13
ConsensusddGGGCKKSGbbn
GC content71.04%
Information content (bits; total / per base)11.884 / 0.914
Data sourcesMethyl-HT-SELEX
Aligned words6205

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.627 0.641 0.436 0.446 0.661 0.718 1.759 1.928 0.889 1.796
Mouse 3 (21) 0.721 0.818 0.57 0.66 0.741 0.884 2.244 2.975 54.585 105.638

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 2 experiments median 0.867 0.83 0.755 0.738 0.634 0.649
best 0.946 0.921 0.853 0.83 0.701 0.714
Methyl HT-SELEX, 1 experiments median 0.946 0.921 0.853 0.83 0.701 0.714
best 0.946 0.921 0.853 0.83 0.701 0.714
Non-Methyl HT-SELEX, 1 experiments median 0.788 0.739 0.656 0.646 0.566 0.583
best 0.788 0.739 0.656 0.646 0.566 0.583
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyThree-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamilyKr-like {2.3.1.2} (TFClass)
TFClass IDTFClass: 2.3.1.2.3
HGNCHGNC:16516
MGIMGI:1342773
EntrezGene (human)GeneID:51274
(SSTAR profile)
EntrezGene (mouse)GeneID:16599
(SSTAR profile)
UniProt ID (human)KLF3_HUMAN
UniProt ID (mouse)KLF3_MOUSE
UniProt AC (human)P57682
(TFClass)
UniProt AC (mouse)Q60980
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 3 mouse
HT-SELEX 1
Methyl-HT-SELEX 1
PCM
ACGT
012054.0620.01662.01869.0
022415.0507.0870.02413.0
0322.00.06179.04.0
040.01.06204.00.0
050.02.06203.00.0
0656.05328.00.0821.0
0732.00.02781.03392.0
08112.0725.02776.02592.0
09198.02474.03279.0254.0
10177.0156.05635.0237.0
11140.02396.02044.01625.0
12571.253235.25641.251757.25
131133.252277.251306.251488.25
PFM
ACGT
010.3310.10.2680.301
020.3890.0820.140.389
030.0040.00.9960.001
040.00.01.00.0
050.00.01.00.0
060.0090.8590.00.132
070.0050.00.4480.547
080.0180.1170.4470.418
090.0320.3990.5280.041
100.0290.0250.9080.038
110.0230.3860.3290.262
120.0920.5210.1030.283
130.1830.3670.2110.24
PWM
ACGT
010.28-0.9150.0690.186
020.442-1.115-0.5770.441
03-4.163-6.5671.381-5.526
04-6.567-6.191.385-6.567
05-6.567-5.9171.385-6.567
06-3.2851.233-6.567-0.635
07-3.816-6.5670.5830.782
08-2.61-0.7590.5810.513
09-2.0490.4660.748-1.802
10-2.16-2.2841.289-1.871
11-2.3910.4340.2760.046
12-0.9970.734-0.8810.125
13-0.3130.383-0.172-0.041
Standard thresholds
P-value Threshold
0.001 3.85581
0.0005 5.15511
0.0001 7.502725