KLF3.H12INVITRO.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF3.H12INVITRO.0.PS.A
Gene (human)	KLF3 (GeneCards)
Gene synonyms (human)	BKLF
Gene (mouse)	Klf3
Gene synonyms (mouse)	Bklf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	12
Consensus	dWGGGCGYGKbn
GC content	70.14%
Information content (bits; total / per base)	12.38 / 1.032
Data sources	ChIP-Seq + HT-SELEX
Aligned words	7303

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.632	0.661	0.456	0.474	0.664	0.713	1.874	2.041	3.841	6.432
Mouse	3 (21)	0.754	0.833	0.63	0.702	0.741	0.87	2.591	3.325	61.456	131.523

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.882	0.863	0.744	0.737	0.641	0.651
Overall, 2 experiments	best	0.915	0.899	0.787	0.775	0.669	0.677
Methyl HT-SELEX, 1 experiments	median	0.915	0.899	0.787	0.775	0.669	0.677
Methyl HT-SELEX, 1 experiments	best	0.915	0.899	0.787	0.775	0.669	0.677
Non-Methyl HT-SELEX, 1 experiments	median	0.848	0.828	0.702	0.699	0.613	0.624
Non-Methyl HT-SELEX, 1 experiments	best	0.848	0.828	0.702	0.699	0.613	0.624

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.3
HGNC	HGNC:16516
MGI	MGI:1342773
EntrezGene (human)	GeneID:51274 (SSTAR profile)
EntrezGene (mouse)	GeneID:16599 (SSTAR profile)
UniProt ID (human)	KLF3_HUMAN
UniProt ID (mouse)	KLF3_MOUSE
UniProt AC (human)	P57682 (TFClass)
UniProt AC (mouse)	Q60980 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 3 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	KLF3.H12INVITRO.0.PS.A.pcm
PWM	KLF3.H12INVITRO.0.PS.A.pwm
PFM	KLF3.H12INVITRO.0.PS.A.pfm
Alignment	KLF3.H12INVITRO.0.PS.A.words.tsv
Threshold to P-value map	KLF3.H12INVITRO.0.PS.A.thr
Motif in other formats
JASPAR format	KLF3.H12INVITRO.0.PS.A_jaspar_format.txt
MEME format	KLF3.H12INVITRO.0.PS.A_meme_format.meme
Transfac format	KLF3.H12INVITRO.0.PS.A_transfac_format.txt
Homer format	KLF3.H12INVITRO.0.PS.A_homer_format_0.001.txt KLF3.H12INVITRO.0.PS.A_homer_format_0.0005.txt KLF3.H12INVITRO.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2666.5	934.5	1863.5	1838.5
02	3551.75	160.75	1139.75	2450.75
03	351.0	16.0	6824.0	112.0
04	7.0	64.0	7207.0	25.0
05	9.0	0.0	7293.0	1.0
06	107.0	7089.0	1.0	106.0
07	256.0	2.0	6879.0	166.0
08	225.0	1768.0	97.0	5213.0
09	469.0	280.0	6125.0	429.0
10	765.0	781.0	4971.0	786.0
11	501.25	3009.25	782.25	3010.25
12	1318.25	2676.25	1503.25	1805.25

PFM

	A	C	G	T
01	0.365	0.128	0.255	0.252
02	0.486	0.022	0.156	0.336
03	0.048	0.002	0.934	0.015
04	0.001	0.009	0.987	0.003
05	0.001	0.0	0.999	0.0
06	0.015	0.971	0.0	0.015
07	0.035	0.0	0.942	0.023
08	0.031	0.242	0.013	0.714
09	0.064	0.038	0.839	0.059
10	0.105	0.107	0.681	0.108
11	0.069	0.412	0.107	0.412
12	0.181	0.366	0.206	0.247

PWM

	A	C	G	T
01	0.378	-0.669	0.02	0.007
02	0.665	-2.417	-0.47	0.294
03	-1.644	-4.608	1.318	-2.773
04	-5.289	-3.318	1.372	-4.207
05	-5.093	-6.712	1.384	-6.34
06	-2.818	1.356	-6.34	-2.827
07	-1.957	-6.07	1.326	-2.386
08	-2.085	-0.032	-2.914	1.048
09	-1.356	-1.868	1.21	-1.444
10	-0.868	-0.848	1.001	-0.841
11	-1.289	0.499	-0.846	0.5
12	-0.325	0.382	-0.194	-0.011

Standard thresholds

P-value	Threshold
0.001	3.79696
0.0005	4.962335
0.0001	7.219565