KLF3.H12CORE.0.PS.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF3.H12CORE.0.PS.A
Gene (human)	KLF3 (GeneCards)
Gene synonyms (human)	BKLF
Gene (mouse)	Klf3
Gene synonyms (mouse)	Bklf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	18
Consensus	nnndGGGYGKGKYhnnnn
GC content	66.51%
Information content (bits; total / per base)	12.209 / 0.678
Data sources	ChIP-Seq + HT-SELEX
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.688	0.7	0.507	0.535	0.788	0.832	3.031	3.144	5.251	7.215
Mouse	3 (21)	0.798	0.89	0.657	0.771	0.87	0.958	3.727	4.699	73.77	177.509

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 2 experiments	median	0.773	0.723	0.673	0.648	0.592	0.593
Overall, 2 experiments	best	0.801	0.748	0.703	0.671	0.617	0.611
Methyl HT-SELEX, 1 experiments	median	0.801	0.748	0.703	0.671	0.617	0.611
Methyl HT-SELEX, 1 experiments	best	0.801	0.748	0.703	0.671	0.617	0.611
Non-Methyl HT-SELEX, 1 experiments	median	0.744	0.698	0.643	0.625	0.567	0.574
Non-Methyl HT-SELEX, 1 experiments	best	0.744	0.698	0.643	0.625	0.567	0.574

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.3
HGNC	HGNC:16516
MGI	MGI:1342773
EntrezGene (human)	GeneID:51274 (SSTAR profile)
EntrezGene (mouse)	GeneID:16599 (SSTAR profile)
UniProt ID (human)	KLF3_HUMAN
UniProt ID (mouse)	KLF3_MOUSE
UniProt AC (human)	P57682 (TFClass)
UniProt AC (mouse)	Q60980 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 3 mouse
HT-SELEX	1
Methyl-HT-SELEX	1

PCM	KLF3.H12CORE.0.PS.A.pcm
PWM	KLF3.H12CORE.0.PS.A.pwm
PFM	KLF3.H12CORE.0.PS.A.pfm
Alignment	KLF3.H12CORE.0.PS.A.words.tsv
Threshold to P-value map	KLF3.H12CORE.0.PS.A.thr
Motif in other formats
JASPAR format	KLF3.H12CORE.0.PS.A_jaspar_format.txt
MEME format	KLF3.H12CORE.0.PS.A_meme_format.meme
Transfac format	KLF3.H12CORE.0.PS.A_transfac_format.txt
Homer format	KLF3.H12CORE.0.PS.A_homer_format_0.001.txt KLF3.H12CORE.0.PS.A_homer_format_0.0005.txt KLF3.H12CORE.0.PS.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	238.0	199.0	349.0	213.0
02	241.0	211.0	359.0	188.0
03	293.0	307.0	205.0	194.0
04	360.0	43.0	213.0	383.0
05	59.0	1.0	936.0	3.0
06	4.0	0.0	989.0	6.0
07	2.0	8.0	986.0	3.0
08	59.0	407.0	2.0	531.0
09	9.0	4.0	978.0	8.0
10	20.0	15.0	487.0	477.0
11	66.0	13.0	874.0	46.0
12	72.0	31.0	800.0	96.0
13	71.0	622.0	56.0	250.0
14	200.0	372.0	149.0	278.0
15	168.0	258.0	370.0	203.0
16	202.0	292.0	296.0	209.0
17	206.0	235.0	309.0	249.0
18	197.0	240.0	344.0	218.0

PFM

	A	C	G	T
01	0.238	0.199	0.349	0.213
02	0.241	0.211	0.359	0.188
03	0.293	0.307	0.205	0.194
04	0.36	0.043	0.213	0.383
05	0.059	0.001	0.937	0.003
06	0.004	0.0	0.99	0.006
07	0.002	0.008	0.987	0.003
08	0.059	0.407	0.002	0.532
09	0.009	0.004	0.979	0.008
10	0.02	0.015	0.487	0.477
11	0.066	0.013	0.875	0.046
12	0.072	0.031	0.801	0.096
13	0.071	0.623	0.056	0.25
14	0.2	0.372	0.149	0.278
15	0.168	0.258	0.37	0.203
16	0.202	0.292	0.296	0.209
17	0.206	0.235	0.309	0.249
18	0.197	0.24	0.344	0.218

PWM

	A	C	G	T
01	-0.048	-0.225	0.333	-0.158
02	-0.035	-0.167	0.361	-0.282
03	0.159	0.205	-0.196	-0.251
04	0.364	-1.727	-0.158	0.425
05	-1.421	-4.524	1.316	-3.974
06	-3.782	-4.981	1.371	-3.483
07	-4.212	-3.252	1.368	-3.974
08	-1.421	0.486	-4.212	0.751
09	-3.155	-3.782	1.36	-3.252
10	-2.449	-2.71	0.664	0.644
11	-1.312	-2.838	1.248	-1.662
12	-1.227	-2.039	1.159	-0.945
13	-1.241	0.908	-1.472	0.001
14	-0.22	0.396	-0.512	0.106
15	-0.393	0.032	0.391	-0.206
16	-0.211	0.155	0.169	-0.177
17	-0.191	-0.06	0.212	-0.003
18	-0.235	-0.04	0.318	-0.135

Standard thresholds

P-value	Threshold
0.001	3.97251
0.0005	5.07631
0.0001	7.30691