KLF17.H12INVITRO.0.M.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF17.H12INVITRO.0.M.C
Gene (human)	KLF17 (GeneCards)
Gene synonyms (human)	ZNF393
Gene (mouse)	Klf17
Gene synonyms (mouse)	Gzf, Zfp393, Znf393
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	C

Motif length	14
Consensus	nddAGGGCGTGKYn
GC content	60.54%
Information content (bits; total / per base)	14.493 / 1.035
Data sources	Methyl-HT-SELEX
Aligned words	8288

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.664	0.672	0.468	0.496	0.714	0.722	1.861	1.934	3.051	4.194

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Methyl HT-SELEX, 1 experiments	median	0.993	0.989	0.972	0.963	0.862	0.865
Methyl HT-SELEX, 1 experiments	best	0.993	0.989	0.972	0.963	0.862	0.865

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.17
HGNC	HGNC:18830
MGI	MGI:2181068
EntrezGene (human)	GeneID:128209 (SSTAR profile)
EntrezGene (mouse)	GeneID:75753 (SSTAR profile)
UniProt ID (human)	KLF17_HUMAN
UniProt ID (mouse)	KLF17_MOUSE
UniProt AC (human)	Q5JT82 (TFClass)
UniProt AC (mouse)	Q8CFA7 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	0
Methyl-HT-SELEX	1

PCM	KLF17.H12INVITRO.0.M.C.pcm
PWM	KLF17.H12INVITRO.0.M.C.pwm
PFM	KLF17.H12INVITRO.0.M.C.pfm
Alignment	KLF17.H12INVITRO.0.M.C.words.tsv
Threshold to P-value map	KLF17.H12INVITRO.0.M.C.thr
Motif in other formats
JASPAR format	KLF17.H12INVITRO.0.M.C_jaspar_format.txt
MEME format	KLF17.H12INVITRO.0.M.C_meme_format.meme
Transfac format	KLF17.H12INVITRO.0.M.C_transfac_format.txt
Homer format	KLF17.H12INVITRO.0.M.C_homer_format_0.001.txt KLF17.H12INVITRO.0.M.C_homer_format_0.0005.txt KLF17.H12INVITRO.0.M.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2228.75	1208.75	2349.75	2500.75
02	1685.0	1305.0	1769.0	3529.0
03	3127.25	483.25	1556.25	3121.25
04	6648.0	381.0	279.0	980.0
05	613.0	0.0	7666.0	9.0
06	0.0	1.0	8287.0	0.0
07	0.0	0.0	8288.0	0.0
08	543.0	6410.0	1.0	1334.0
09	6.0	0.0	8282.0	0.0
10	7.0	18.0	545.0	7718.0
11	144.0	7.0	8097.0	40.0
12	783.75	224.75	3952.75	3326.75
13	728.75	5060.75	750.75	1747.75
14	2721.0	1400.0	1921.0	2246.0

PFM

	A	C	G	T
01	0.269	0.146	0.284	0.302
02	0.203	0.157	0.213	0.426
03	0.377	0.058	0.188	0.377
04	0.802	0.046	0.034	0.118
05	0.074	0.0	0.925	0.001
06	0.0	0.0	1.0	0.0
07	0.0	0.0	1.0	0.0
08	0.066	0.773	0.0	0.161
09	0.001	0.0	0.999	0.0
10	0.001	0.002	0.066	0.931
11	0.017	0.001	0.977	0.005
12	0.095	0.027	0.477	0.401
13	0.088	0.611	0.091	0.211
14	0.328	0.169	0.232	0.271

PWM

	A	C	G	T
01	0.073	-0.538	0.126	0.188
02	-0.206	-0.462	-0.158	0.532
03	0.411	-1.452	-0.286	0.409
04	1.165	-1.689	-1.998	-0.748
05	-1.215	-6.824	1.307	-5.216
06	-6.824	-6.457	1.385	-6.824
07	-6.824	-6.824	1.385	-6.824
08	-1.336	1.129	-6.457	-0.44
09	-5.526	-6.824	1.385	-6.824
10	-5.412	-4.629	-1.332	1.314
11	-2.652	-5.412	1.362	-3.894
12	-0.97	-2.212	0.645	0.473
13	-1.043	0.892	-1.013	-0.17
14	0.272	-0.392	-0.076	0.081

Standard thresholds

P-value	Threshold
0.001	1.75001
0.0005	3.39481
0.0001	6.69942