KLF16.H12INVITRO.1.P.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF16.H12INVITRO.1.P.B
Gene (human)	KLF16 (GeneCards)
Gene synonyms (human)	BTEB4, NSLP2
Gene (mouse)	Klf16
Gene synonyms (mouse)	Bteb4, Drrf
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	B

Motif length	23
Consensus	SvvRvvRRRGGMRGRGMnSRvRS
GC content	76.31%
Information content (bits; total / per base)	15.502 / 0.674
Data sources	ChIP-Seq
Aligned words	999

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (13)	0.635	0.682	0.433	0.449	0.681	0.834	2.459	3.335	0.149	2.0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.582	0.547	0.568	0.54	0.55	0.532
Overall, 3 experiments	best	0.603	0.558	0.586	0.551	0.563	0.541
Methyl HT-SELEX, 1 experiments	median	0.582	0.547	0.568	0.54	0.55	0.532
Methyl HT-SELEX, 1 experiments	best	0.582	0.547	0.568	0.54	0.55	0.532
Non-Methyl HT-SELEX, 2 experiments	median	0.558	0.534	0.548	0.529	0.534	0.522
Non-Methyl HT-SELEX, 2 experiments	best	0.603	0.558	0.586	0.551	0.563	0.541

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.16
HGNC	HGNC:16857
MGI	MGI:2153049
EntrezGene (human)	GeneID:83855 (SSTAR profile)
EntrezGene (mouse)	GeneID:118445 (SSTAR profile)
UniProt ID (human)	KLF16_HUMAN
UniProt ID (mouse)	KLF16_MOUSE
UniProt AC (human)	Q9BXK1 (TFClass)
UniProt AC (mouse)	P58334 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	1

PCM	KLF16.H12INVITRO.1.P.B.pcm
PWM	KLF16.H12INVITRO.1.P.B.pwm
PFM	KLF16.H12INVITRO.1.P.B.pfm
Alignment	KLF16.H12INVITRO.1.P.B.words.tsv
Threshold to P-value map	KLF16.H12INVITRO.1.P.B.thr
Motif in other formats
JASPAR format	KLF16.H12INVITRO.1.P.B_jaspar_format.txt
MEME format	KLF16.H12INVITRO.1.P.B_meme_format.meme
Transfac format	KLF16.H12INVITRO.1.P.B_transfac_format.txt
Homer format	KLF16.H12INVITRO.1.P.B_homer_format_0.001.txt KLF16.H12INVITRO.1.P.B_homer_format_0.0005.txt KLF16.H12INVITRO.1.P.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	137.0	247.0	566.0	49.0
02	179.0	263.0	515.0	42.0
03	198.0	183.0	503.0	115.0
04	113.0	90.0	718.0	78.0
05	163.0	244.0	540.0	52.0
06	389.0	183.0	294.0	133.0
07	208.0	79.0	658.0	54.0
08	129.0	73.0	773.0	24.0
09	313.0	42.0	598.0	46.0
10	43.0	9.0	929.0	18.0
11	20.0	52.0	916.0	11.0
12	265.0	646.0	11.0	77.0
13	140.0	25.0	782.0	52.0
14	39.0	10.0	917.0	33.0
15	227.0	33.0	702.0	37.0
16	86.0	32.0	850.0	31.0
17	249.0	573.0	148.0	29.0
18	219.0	288.0	306.0	186.0
19	122.0	153.0	606.0	118.0
20	192.0	118.0	654.0	35.0
21	245.0	224.0	459.0	71.0
22	262.0	90.0	603.0	44.0
23	114.0	159.0	670.0	56.0

PFM

	A	C	G	T
01	0.137	0.247	0.567	0.049
02	0.179	0.263	0.516	0.042
03	0.198	0.183	0.504	0.115
04	0.113	0.09	0.719	0.078
05	0.163	0.244	0.541	0.052
06	0.389	0.183	0.294	0.133
07	0.208	0.079	0.659	0.054
08	0.129	0.073	0.774	0.024
09	0.313	0.042	0.599	0.046
10	0.043	0.009	0.93	0.018
11	0.02	0.052	0.917	0.011
12	0.265	0.647	0.011	0.077
13	0.14	0.025	0.783	0.052
14	0.039	0.01	0.918	0.033
15	0.227	0.033	0.703	0.037
16	0.086	0.032	0.851	0.031
17	0.249	0.574	0.148	0.029
18	0.219	0.288	0.306	0.186
19	0.122	0.153	0.607	0.118
20	0.192	0.118	0.655	0.035
21	0.245	0.224	0.459	0.071
22	0.262	0.09	0.604	0.044
23	0.114	0.159	0.671	0.056

PWM

	A	C	G	T
01	-0.595	-0.011	0.814	-1.601
02	-0.33	0.051	0.72	-1.749
03	-0.23	-0.308	0.697	-0.768
04	-0.785	-1.009	1.052	-1.149
05	-0.423	-0.023	0.767	-1.543
06	0.441	-0.308	0.162	-0.624
07	-0.182	-1.136	0.964	-1.507
08	-0.654	-1.214	1.125	-2.28
09	0.224	-1.749	0.869	-1.662
10	-1.727	-3.155	1.309	-2.545
11	-2.449	-1.543	1.295	-2.984
12	0.059	0.946	-2.984	-1.161
13	-0.573	-2.242	1.137	-1.543
14	-1.82	-3.065	1.296	-1.98
15	-0.095	-1.98	1.029	-1.871
16	-1.053	-2.009	1.22	-2.039
17	-0.003	0.827	-0.519	-2.102
18	-0.13	0.142	0.202	-0.292
19	-0.709	-0.486	0.882	-0.742
20	-0.261	-0.742	0.958	-1.924
21	-0.019	-0.108	0.605	-1.241
22	0.048	-1.009	0.877	-1.705
23	-0.776	-0.448	0.983	-1.472

Standard thresholds

P-value	Threshold
0.001	3.24701
0.0005	4.29121
0.0001	6.50751