KLF16.H12INVITRO.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF16.H12INVITRO.0.SM.B
Gene (human)	KLF16 (GeneCards)
Gene synonyms (human)	BTEB4, NSLP2
Gene (mouse)	Klf16
Gene synonyms (mouse)	Bteb4, Drrf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	dRdGGGCGTRd
GC content	69.71%
Information content (bits; total / per base)	13.031 / 1.185
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	6722

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (13)	0.624	0.7	0.436	0.525	0.571	0.71	1.302	1.899	2.143	7.26

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.901	0.833	0.872	0.812	0.813	0.763
Overall, 3 experiments	best	0.902	0.835	0.891	0.826	0.843	0.787
Methyl HT-SELEX, 1 experiments	median	0.902	0.833	0.891	0.826	0.843	0.787
Methyl HT-SELEX, 1 experiments	best	0.902	0.833	0.891	0.826	0.843	0.787
Non-Methyl HT-SELEX, 2 experiments	median	0.76	0.715	0.72	0.684	0.676	0.65
Non-Methyl HT-SELEX, 2 experiments	best	0.901	0.835	0.872	0.812	0.813	0.763

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.16
HGNC	HGNC:16857
MGI	MGI:2153049
EntrezGene (human)	GeneID:83855 (SSTAR profile)
EntrezGene (mouse)	GeneID:118445 (SSTAR profile)
UniProt ID (human)	KLF16_HUMAN
UniProt ID (mouse)	KLF16_MOUSE
UniProt AC (human)	Q9BXK1 (TFClass)
UniProt AC (mouse)	P58334 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	1

PCM	KLF16.H12INVITRO.0.SM.B.pcm
PWM	KLF16.H12INVITRO.0.SM.B.pwm
PFM	KLF16.H12INVITRO.0.SM.B.pfm
Alignment	KLF16.H12INVITRO.0.SM.B.words.tsv
Threshold to P-value map	KLF16.H12INVITRO.0.SM.B.thr
Motif in other formats
JASPAR format	KLF16.H12INVITRO.0.SM.B_jaspar_format.txt
MEME format	KLF16.H12INVITRO.0.SM.B_meme_format.meme
Transfac format	KLF16.H12INVITRO.0.SM.B_transfac_format.txt
Homer format	KLF16.H12INVITRO.0.SM.B_homer_format_0.001.txt KLF16.H12INVITRO.0.SM.B_homer_format_0.0005.txt KLF16.H12INVITRO.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1612.75	941.75	2670.75	1496.75
02	1609.75	316.75	3799.75	995.75
03	1280.0	113.0	3133.0	2196.0
04	1154.0	0.0	5568.0	0.0
05	0.0	0.0	6722.0	0.0
06	0.0	0.0	6722.0	0.0
07	0.0	6703.0	0.0	19.0
08	0.0	0.0	6722.0	0.0
09	0.0	0.0	10.0	6712.0
10	1272.0	85.0	4469.0	896.0
11	1458.5	817.5	2749.5	1696.5

PFM

	A	C	G	T
01	0.24	0.14	0.397	0.223
02	0.239	0.047	0.565	0.148
03	0.19	0.017	0.466	0.327
04	0.172	0.0	0.828	0.0
05	0.0	0.0	1.0	0.0
06	0.0	0.0	1.0	0.0
07	0.0	0.997	0.0	0.003
08	0.0	0.0	1.0	0.0
09	0.0	0.0	0.001	0.999
10	0.189	0.013	0.665	0.133
11	0.217	0.122	0.409	0.252

PWM

	A	C	G	T
01	-0.041	-0.578	0.463	-0.116
02	-0.043	-1.663	0.815	-0.522
03	-0.272	-2.681	0.622	0.267
04	-0.375	-6.638	1.197	-6.638
05	-6.638	-6.638	1.385	-6.638
06	-6.638	-6.638	1.385	-6.638
07	-6.638	1.382	-6.638	-4.374
08	-6.638	-6.638	1.385	-6.638
09	-6.638	-6.638	-4.926	1.384
10	-0.278	-2.96	0.977	-0.628
11	-0.141	-0.719	0.492	0.009

Standard thresholds

P-value	Threshold
0.001	1.33638
0.0005	2.932835
0.0001	7.620255