KLF16.H12CORE.0.SM.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF16.H12CORE.0.SM.B
Gene (human)	KLF16 (GeneCards)
Gene synonyms (human)	BTEB4, NSLP2
Gene (mouse)	Klf16
Gene synonyms (mouse)	Bteb4, Drrf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	11
Consensus	dddGGGCGTRd
GC content	70.26%
Information content (bits; total / per base)	11.728 / 1.066
Data sources	HT-SELEX + Methyl-HT-SELEX
Aligned words	9252

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	2 (13)	0.648	0.74	0.472	0.566	0.638	0.796	1.631	2.369	6.569	10.071

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 3 experiments	median	0.894	0.83	0.865	0.803	0.815	0.76
Overall, 3 experiments	best	0.901	0.831	0.872	0.808	0.832	0.773
Methyl HT-SELEX, 1 experiments	median	0.901	0.831	0.872	0.808	0.832	0.773
Methyl HT-SELEX, 1 experiments	best	0.901	0.831	0.872	0.808	0.832	0.773
Non-Methyl HT-SELEX, 2 experiments	median	0.761	0.715	0.715	0.681	0.674	0.648
Non-Methyl HT-SELEX, 2 experiments	best	0.894	0.83	0.865	0.803	0.815	0.76

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.16
HGNC	HGNC:16857
MGI	MGI:2153049
EntrezGene (human)	GeneID:83855 (SSTAR profile)
EntrezGene (mouse)	GeneID:118445 (SSTAR profile)
UniProt ID (human)	KLF16_HUMAN
UniProt ID (mouse)	KLF16_MOUSE
UniProt AC (human)	Q9BXK1 (TFClass)
UniProt AC (mouse)	P58334 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	2 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	1

PCM	KLF16.H12CORE.0.SM.B.pcm
PWM	KLF16.H12CORE.0.SM.B.pwm
PFM	KLF16.H12CORE.0.SM.B.pfm
Alignment	KLF16.H12CORE.0.SM.B.words.tsv
Threshold to P-value map	KLF16.H12CORE.0.SM.B.thr
Motif in other formats
JASPAR format	KLF16.H12CORE.0.SM.B_jaspar_format.txt
MEME format	KLF16.H12CORE.0.SM.B_meme_format.meme
Transfac format	KLF16.H12CORE.0.SM.B_transfac_format.txt
Homer format	KLF16.H12CORE.0.SM.B_homer_format_0.001.txt KLF16.H12CORE.0.SM.B_homer_format_0.0005.txt KLF16.H12CORE.0.SM.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2248.25	1294.25	3731.25	1978.25
02	2236.0	522.0	5177.0	1317.0
03	1891.0	189.0	4251.0	2921.0
04	1551.0	7.0	7555.0	139.0
05	0.0	4.0	9245.0	3.0
06	0.0	0.0	9252.0	0.0
07	122.0	8660.0	0.0	470.0
08	2.0	0.0	9250.0	0.0
09	99.0	134.0	1120.0	7899.0
10	1801.25	216.25	5967.25	1267.25
11	2079.5	1101.5	3831.5	2239.5

PFM

	A	C	G	T
01	0.243	0.14	0.403	0.214
02	0.242	0.056	0.56	0.142
03	0.204	0.02	0.459	0.316
04	0.168	0.001	0.817	0.015
05	0.0	0.0	0.999	0.0
06	0.0	0.0	1.0	0.0
07	0.013	0.936	0.0	0.051
08	0.0	0.0	1.0	0.0
09	0.011	0.014	0.121	0.854
10	0.195	0.023	0.645	0.137
11	0.225	0.119	0.414	0.242

PWM

	A	C	G	T
01	-0.028	-0.58	0.478	-0.156
02	-0.034	-1.485	0.805	-0.562
03	-0.201	-2.494	0.608	0.233
04	-0.399	-5.519	1.183	-2.797
05	-6.922	-5.909	1.385	-6.083
06	-6.922	-6.922	1.386	-6.922
07	-2.925	1.319	-6.922	-1.59
08	-6.293	-6.922	1.385	-6.922
09	-3.129	-2.833	-0.724	1.227
10	-0.25	-2.36	0.947	-0.601
11	-0.106	-0.741	0.504	-0.032

Standard thresholds

P-value	Threshold
0.001	3.96591
0.0005	5.261625
0.0001	7.59174