KLF15.H12RSNP.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF15.H12RSNP.0.S.B
Gene (human)	KLF15 (GeneCards)
Gene synonyms (human)	KKLF
Gene (mouse)	Klf15
Gene synonyms (mouse)	Cklf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	dddRKGGGYGKKKn
GC content	70.85%
Information content (bits; total / per base)	11.777 / 0.841
Data sources	HT-SELEX
Aligned words	9293

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.82	0.855	0.627	0.664	0.84	0.868	2.624	2.668	54.0	94.42

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.809	0.733	0.748	0.69	0.654	0.633
Non-Methyl HT-SELEX, 2 experiments	best	0.813	0.739	0.759	0.694	0.681	0.645

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.583	0.145	0.374	0.191

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.15
HGNC	HGNC:14536
MGI	MGI:1929988
EntrezGene (human)	GeneID:28999 (SSTAR profile)
EntrezGene (mouse)	GeneID:66277 (SSTAR profile)
UniProt ID (human)	KLF15_HUMAN
UniProt ID (mouse)	KLF15_MOUSE
UniProt AC (human)	Q9UIH9 (TFClass)
UniProt AC (mouse)	Q9EPW2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	KLF15.H12RSNP.0.S.B.pcm
PWM	KLF15.H12RSNP.0.S.B.pwm
PFM	KLF15.H12RSNP.0.S.B.pfm
Alignment	KLF15.H12RSNP.0.S.B.words.tsv
Threshold to P-value map	KLF15.H12RSNP.0.S.B.thr
Motif in other formats
JASPAR format	KLF15.H12RSNP.0.S.B_jaspar_format.txt
MEME format	KLF15.H12RSNP.0.S.B_meme_format.meme
Transfac format	KLF15.H12RSNP.0.S.B_transfac_format.txt
Homer format	KLF15.H12RSNP.0.S.B_homer_format_0.001.txt KLF15.H12RSNP.0.S.B_homer_format_0.0005.txt KLF15.H12RSNP.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2056.5	1317.5	3920.5	1998.5
02	2404.25	1081.25	4047.25	1760.25
03	2412.0	700.0	4729.0	1452.0
04	1743.0	171.0	6447.0	932.0
05	1558.0	101.0	4492.0	3142.0
06	545.0	0.0	8572.0	176.0
07	30.0	312.0	8944.0	7.0
08	1.0	0.0	9292.0	0.0
09	1581.0	6068.0	0.0	1644.0
10	126.0	0.0	9157.0	10.0
11	317.0	122.0	3716.0	5138.0
12	945.0	131.0	6866.0	1351.0
13	1278.25	606.25	5549.25	1859.25
14	1335.75	2974.75	2856.75	2125.75

PFM

	A	C	G	T
01	0.221	0.142	0.422	0.215
02	0.259	0.116	0.436	0.189
03	0.26	0.075	0.509	0.156
04	0.188	0.018	0.694	0.1
05	0.168	0.011	0.483	0.338
06	0.059	0.0	0.922	0.019
07	0.003	0.034	0.962	0.001
08	0.0	0.0	1.0	0.0
09	0.17	0.653	0.0	0.177
10	0.014	0.0	0.985	0.001
11	0.034	0.013	0.4	0.553
12	0.102	0.014	0.739	0.145
13	0.138	0.065	0.597	0.2
14	0.144	0.32	0.307	0.229

PWM

	A	C	G	T
01	-0.122	-0.566	0.523	-0.15
02	0.034	-0.764	0.555	-0.277
03	0.037	-1.197	0.71	-0.469
04	-0.287	-2.597	1.02	-0.912
05	-0.399	-3.114	0.659	0.302
06	-1.447	-6.926	1.305	-2.568
07	-4.277	-2.001	1.347	-5.523
08	-6.563	-6.926	1.385	-6.926
09	-0.384	0.959	-6.926	-0.345
10	-2.897	-6.926	1.371	-5.243
11	-1.986	-2.929	0.469	0.793
12	-0.898	-2.859	1.083	-0.541
13	-0.597	-1.341	0.87	-0.223
14	-0.553	0.247	0.207	-0.089

Standard thresholds

P-value	Threshold
0.001	4.14196
0.0005	5.26481
0.0001	7.39006