KLF15.H12CORE.0.S.B motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF15.H12CORE.0.S.B
Gene (human)	KLF15 (GeneCards)
Gene synonyms (human)	KKLF
Gene (mouse)	Klf15
Gene synonyms (mouse)	Cklf
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	B

Motif length	14
Consensus	dddRKGGGCGTKKb
GC content	72.5%
Information content (bits; total / per base)	13.381 / 0.956
Data sources	HT-SELEX
Aligned words	7121

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (5)	0.826	0.861	0.647	0.685	0.841	0.871	2.712	2.776	59.77	105.745

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Non-Methyl HT-SELEX, 2 experiments	median	0.831	0.767	0.755	0.707	0.655	0.641
Non-Methyl HT-SELEX, 2 experiments	best	0.835	0.776	0.769	0.711	0.683	0.654

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.565	0.153	0.379	0.167

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.15
HGNC	HGNC:14536
MGI	MGI:1929988
EntrezGene (human)	GeneID:28999 (SSTAR profile)
EntrezGene (mouse)	GeneID:66277 (SSTAR profile)
UniProt ID (human)	KLF15_HUMAN
UniProt ID (mouse)	KLF15_MOUSE
UniProt AC (human)	Q9UIH9 (TFClass)
UniProt AC (mouse)	Q9EPW2 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	2
Methyl-HT-SELEX	0

PCM	KLF15.H12CORE.0.S.B.pcm
PWM	KLF15.H12CORE.0.S.B.pwm
PFM	KLF15.H12CORE.0.S.B.pfm
Alignment	KLF15.H12CORE.0.S.B.words.tsv
Threshold to P-value map	KLF15.H12CORE.0.S.B.thr
Motif in other formats
JASPAR format	KLF15.H12CORE.0.S.B_jaspar_format.txt
MEME format	KLF15.H12CORE.0.S.B_meme_format.meme
Transfac format	KLF15.H12CORE.0.S.B_transfac_format.txt
Homer format	KLF15.H12CORE.0.S.B_homer_format_0.001.txt KLF15.H12CORE.0.S.B_homer_format_0.0005.txt KLF15.H12CORE.0.S.B_homer_format_0.0001.txt

PCM

	A	C	G	T
01	1482.75	953.75	3153.75	1530.75
02	1803.25	842.25	3084.25	1391.25
03	1959.0	509.0	3501.0	1152.0
04	1298.0	131.0	4953.0	739.0
05	811.0	43.0	3837.0	2430.0
06	304.0	2.0	6751.0	64.0
07	12.0	105.0	7000.0	4.0
08	0.0	0.0	7121.0	0.0
09	458.0	6273.0	0.0	390.0
10	9.0	0.0	7111.0	1.0
11	93.0	18.0	1846.0	5164.0
12	633.0	97.0	5514.0	877.0
13	875.5	405.5	4440.5	1399.5
14	907.5	2546.5	2042.5	1624.5

PFM

	A	C	G	T
01	0.208	0.134	0.443	0.215
02	0.253	0.118	0.433	0.195
03	0.275	0.071	0.492	0.162
04	0.182	0.018	0.696	0.104
05	0.114	0.006	0.539	0.341
06	0.043	0.0	0.948	0.009
07	0.002	0.015	0.983	0.001
08	0.0	0.0	1.0	0.0
09	0.064	0.881	0.0	0.055
10	0.001	0.0	0.999	0.0
11	0.013	0.003	0.259	0.725
12	0.089	0.014	0.774	0.123
13	0.123	0.057	0.624	0.197
14	0.127	0.358	0.287	0.228

PWM

	A	C	G	T
01	-0.183	-0.623	0.571	-0.151
02	0.013	-0.747	0.549	-0.246
03	0.096	-1.249	0.676	-0.435
04	-0.315	-2.594	1.022	-0.877
05	-0.785	-3.674	0.767	0.311
06	-1.761	-6.046	1.332	-3.293
07	-4.831	-2.811	1.368	-5.658
08	-6.689	-6.689	1.385	-6.689
09	-1.354	1.259	-6.689	-1.514
10	-5.068	-6.689	1.384	-6.317
11	-2.93	-4.479	0.036	1.064
12	-1.032	-2.888	1.13	-0.707
13	-0.708	-1.475	0.913	-0.24
14	-0.673	0.358	0.137	-0.091

Standard thresholds

P-value	Threshold
0.001	3.14671
0.0005	4.50326
0.0001	7.08937