KLF14.H12RSNP.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF14.H12RSNP.1.P.C
Gene (human)	KLF14 (GeneCards)
Gene synonyms (human)	BTEB5
Gene (mouse)	Klf14
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	23
Consensus	GSvSGvGGMGGvGSvRGvSSSRG
GC content	86.8%
Information content (bits; total / per base)	20.397 / 0.887
Data sources	ChIP-Seq
Aligned words	1000

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.649	0.658	0.427	0.435	0.633	0.692	2.274	2.447	0.0	0

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.525	0.513	0.523	0.512	0.519	0.511
Overall, 4 experiments	best	0.642	0.587	0.613	0.572	0.583	0.556
Methyl HT-SELEX, 1 experiments	median	0.547	0.524	0.544	0.523	0.537	0.521
Methyl HT-SELEX, 1 experiments	best	0.547	0.524	0.544	0.523	0.537	0.521
Non-Methyl HT-SELEX, 3 experiments	median	0.503	0.503	0.501	0.501	0.501	0.501
Non-Methyl HT-SELEX, 3 experiments	best	0.642	0.587	0.613	0.572	0.583	0.556

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.624	0.017	0.109	0.04

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.14
HGNC	HGNC:23025
MGI	MGI:3577024
EntrezGene (human)	GeneID:136259 (SSTAR profile)
EntrezGene (mouse)	GeneID:619665 (SSTAR profile)
UniProt ID (human)	KLF14_HUMAN
UniProt ID (mouse)	KLF14_MOUSE
UniProt AC (human)	Q8TD94 (TFClass)
UniProt AC (mouse)	Q19A41 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	KLF14.H12RSNP.1.P.C.pcm
PWM	KLF14.H12RSNP.1.P.C.pwm
PFM	KLF14.H12RSNP.1.P.C.pfm
Alignment	KLF14.H12RSNP.1.P.C.words.tsv
Threshold to P-value map	KLF14.H12RSNP.1.P.C.thr
Motif in other formats
JASPAR format	KLF14.H12RSNP.1.P.C_jaspar_format.txt
MEME format	KLF14.H12RSNP.1.P.C_meme_format.meme
Transfac format	KLF14.H12RSNP.1.P.C_transfac_format.txt
Homer format	KLF14.H12RSNP.1.P.C_homer_format_0.001.txt KLF14.H12RSNP.1.P.C_homer_format_0.0005.txt KLF14.H12RSNP.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	46.0	96.0	811.0	47.0
02	55.0	152.0	769.0	24.0
03	227.0	365.0	379.0	29.0
04	163.0	217.0	574.0	46.0
05	37.0	16.0	923.0	24.0
06	136.0	293.0	528.0	43.0
07	81.0	38.0	862.0	19.0
08	12.0	13.0	967.0	8.0
09	188.0	751.0	10.0	51.0
10	46.0	26.0	865.0	63.0
11	16.0	12.0	951.0	21.0
12	114.0	285.0	538.0	63.0
13	35.0	39.0	895.0	31.0
14	77.0	362.0	523.0	38.0
15	112.0	510.0	287.0	91.0
16	119.0	52.0	769.0	60.0
17	37.0	72.0	862.0	29.0
18	124.0	305.0	514.0	57.0
19	104.0	184.0	675.0	37.0
20	100.0	164.0	714.0	22.0
21	139.0	362.0	473.0	26.0
22	144.0	89.0	733.0	34.0
23	43.0	52.0	886.0	19.0

PFM

	A	C	G	T
01	0.046	0.096	0.811	0.047
02	0.055	0.152	0.769	0.024
03	0.227	0.365	0.379	0.029
04	0.163	0.217	0.574	0.046
05	0.037	0.016	0.923	0.024
06	0.136	0.293	0.528	0.043
07	0.081	0.038	0.862	0.019
08	0.012	0.013	0.967	0.008
09	0.188	0.751	0.01	0.051
10	0.046	0.026	0.865	0.063
11	0.016	0.012	0.951	0.021
12	0.114	0.285	0.538	0.063
13	0.035	0.039	0.895	0.031
14	0.077	0.362	0.523	0.038
15	0.112	0.51	0.287	0.091
16	0.119	0.052	0.769	0.06
17	0.037	0.072	0.862	0.029
18	0.124	0.305	0.514	0.057
19	0.104	0.184	0.675	0.037
20	0.1	0.164	0.714	0.022
21	0.139	0.362	0.473	0.026
22	0.144	0.089	0.733	0.034
23	0.043	0.052	0.886	0.019

PWM

	A	C	G	T
01	-1.663	-0.946	1.172	-1.642
02	-1.49	-0.493	1.119	-2.281
03	-0.096	0.376	0.414	-2.103
04	-0.424	-0.141	0.827	-1.663
05	-1.872	-2.653	1.301	-2.281
06	-0.603	0.158	0.744	-1.728
07	-1.113	-1.846	1.233	-2.497
08	-2.909	-2.839	1.348	-3.253
09	-0.283	1.095	-3.066	-1.563
10	-1.663	-2.206	1.236	-1.358
11	-2.653	-2.909	1.331	-2.405
12	-0.777	0.13	0.763	-1.358
13	-1.925	-1.821	1.27	-2.04
14	-1.162	0.368	0.735	-1.846
15	-0.795	0.709	0.137	-0.999
16	-0.735	-1.544	1.119	-1.406
17	-1.872	-1.228	1.233	-2.103
18	-0.694	0.198	0.717	-1.455
19	-0.867	-0.304	0.989	-1.872
20	-0.906	-0.418	1.045	-2.362
21	-0.582	0.368	0.634	-2.206
22	-0.547	-1.02	1.071	-1.952
23	-1.728	-1.544	1.26	-2.497

Standard thresholds

P-value	Threshold
0.001	1.24971
0.0005	2.49486
0.0001	5.15746