KLF14.H12RSNP.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF14.H12RSNP.0.PSM.A
Gene (human)	KLF14 (GeneCards)
Gene synonyms (human)	BTEB5
Gene (mouse)	Klf14
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	16
Consensus	nnddRKGGGCGTGdbn
GC content	67.55%
Information content (bits; total / per base)	14.301 / 0.894
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9963

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.73	0.754	0.58	0.615	0.755	0.758	2.568	2.602	8.398	14.538

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.851	0.829	0.781	0.77	0.734	0.726
Overall, 4 experiments	best	0.984	0.97	0.978	0.963	0.958	0.939
Methyl HT-SELEX, 1 experiments	median	0.959	0.926	0.95	0.916	0.917	0.881
Methyl HT-SELEX, 1 experiments	best	0.959	0.926	0.95	0.916	0.917	0.881
Non-Methyl HT-SELEX, 3 experiments	median	0.743	0.732	0.611	0.624	0.551	0.571
Non-Methyl HT-SELEX, 3 experiments	best	0.984	0.97	0.978	0.963	0.958	0.939

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.611	0.063	0.269	0.233

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.14
HGNC	HGNC:23025
MGI	MGI:3577024
EntrezGene (human)	GeneID:136259 (SSTAR profile)
EntrezGene (mouse)	GeneID:619665 (SSTAR profile)
UniProt ID (human)	KLF14_HUMAN
UniProt ID (mouse)	KLF14_MOUSE
UniProt AC (human)	Q8TD94 (TFClass)
UniProt AC (mouse)	Q19A41 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	KLF14.H12RSNP.0.PSM.A.pcm
PWM	KLF14.H12RSNP.0.PSM.A.pwm
PFM	KLF14.H12RSNP.0.PSM.A.pfm
Alignment	KLF14.H12RSNP.0.PSM.A.words.tsv
Threshold to P-value map	KLF14.H12RSNP.0.PSM.A.thr
Motif in other formats
JASPAR format	KLF14.H12RSNP.0.PSM.A_jaspar_format.txt
MEME format	KLF14.H12RSNP.0.PSM.A_meme_format.meme
Transfac format	KLF14.H12RSNP.0.PSM.A_transfac_format.txt
Homer format	KLF14.H12RSNP.0.PSM.A_homer_format_0.001.txt KLF14.H12RSNP.0.PSM.A_homer_format_0.0005.txt KLF14.H12RSNP.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2329.0	1773.0	3710.0	2151.0
02	2490.5	1737.5	3672.5	2062.5
03	3079.0	1286.0	3633.0	1965.0
04	3185.0	1304.0	3670.0	1804.0
05	2545.0	333.0	6262.0	823.0
06	1207.0	39.0	5127.0	3590.0
07	1064.0	11.0	8865.0	23.0
08	5.0	10.0	9948.0	0.0
09	6.0	1.0	9951.0	5.0
10	33.0	9886.0	4.0	40.0
11	3.0	2.0	9954.0	4.0
12	23.0	47.0	275.0	9618.0
13	1292.0	79.0	8124.0	468.0
14	1881.0	518.0	5600.0	1964.0
15	1226.5	3988.5	2053.5	2694.5
16	2012.75	2265.75	3543.75	2140.75

PFM

	A	C	G	T
01	0.234	0.178	0.372	0.216
02	0.25	0.174	0.369	0.207
03	0.309	0.129	0.365	0.197
04	0.32	0.131	0.368	0.181
05	0.255	0.033	0.629	0.083
06	0.121	0.004	0.515	0.36
07	0.107	0.001	0.89	0.002
08	0.001	0.001	0.998	0.0
09	0.001	0.0	0.999	0.001
10	0.003	0.992	0.0	0.004
11	0.0	0.0	0.999	0.0
12	0.002	0.005	0.028	0.965
13	0.13	0.008	0.815	0.047
14	0.189	0.052	0.562	0.197
15	0.123	0.4	0.206	0.27
16	0.202	0.227	0.356	0.215

PWM

	A	C	G	T
01	-0.067	-0.34	0.398	-0.147
02	-0.0	-0.36	0.388	-0.188
03	0.212	-0.66	0.377	-0.237
04	0.246	-0.646	0.387	-0.322
05	0.022	-2.006	0.921	-1.106
06	-0.723	-4.1	0.721	0.365
07	-0.849	-5.233	1.269	-4.59
08	-5.833	-5.312	1.384	-6.988
09	-5.705	-6.627	1.384	-5.833
10	-4.257	1.378	-5.98	-4.076
11	-6.153	-6.362	1.385	-5.98
12	-4.59	-3.923	-2.196	1.35
13	-0.656	-3.423	1.182	-1.668
14	-0.28	-1.567	0.81	-0.237
15	-0.707	0.47	-0.193	0.079
16	-0.213	-0.095	0.352	-0.151

Standard thresholds

P-value	Threshold
0.001	1.92616
0.0005	3.43031
0.0001	6.70711