| Motif | KLF14.H12INVIVO.1.P.C |
| Gene (human) | KLF14 (GeneCards) |
| Gene synonyms (human) | BTEB5 |
| Gene (mouse) | Klf14 |
| Gene synonyms (mouse) | |
| LOGO |  |
| LOGO (reverse complement) |  |
| Motif subtype | 1 |
| Quality | C |
| Motif | KLF14.H12INVIVO.1.P.C |
| Gene (human) | KLF14 (GeneCards) |
| Gene synonyms (human) | BTEB5 |
| Gene (mouse) | Klf14 |
| Gene synonyms (mouse) | |
| LOGO | |
| LOGO (reverse complement) | |
| Motif subtype | 1 |
| Quality | C |
| Motif length | 23 |
| Consensus | dRvdRdRGGYGKRdvnvdRdbdR |
| GC content | 67.07% |
| Information content (bits; total / per base) | 12.032 / 0.523 |
| Data sources | ChIP-Seq |
| Aligned words | 997 |
| ChIP-Seq benchmarking | Num. of experiments (peaksets) | auROC, median | auROC, best | auPRC, median | auPRC, best | pseudo-auROC, median | pseudo-auROC, best | pseudo-log-auROC, median | pseudo-log-auROC, best | Centrality, median | Centrality, best |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Human | 1 (6) | 0.688 | 0.712 | 0.492 | 0.524 | 0.809 | 0.824 | 3.045 | 3.099 | 4.432 | 9.62 |
| HT-SELEX benchmarking | auROC10 | auPRC10 | auROC25 | auPRC25 | auROC50 | auPRC50 | |
|---|---|---|---|---|---|---|---|
| Overall, 4 experiments | median | 0.68 | 0.635 | 0.65 | 0.614 | 0.621 | 0.593 |
| best | 0.867 | 0.799 | 0.831 | 0.766 | 0.774 | 0.721 | |
| Methyl HT-SELEX, 1 experiments | median | 0.81 | 0.734 | 0.779 | 0.708 | 0.733 | 0.676 |
| best | 0.81 | 0.734 | 0.779 | 0.708 | 0.733 | 0.676 | |
| Non-Methyl HT-SELEX, 3 experiments | median | 0.55 | 0.536 | 0.52 | 0.519 | 0.508 | 0.511 |
| best | 0.867 | 0.799 | 0.831 | 0.766 | 0.774 | 0.721 | |
| rSNP benchmarking, SNP-SELEX | auROC | auPRC | Pearson r | Kendall tau |
|---|---|---|---|---|
| batch 2 | 0.541 | 0.01 | 0.314 | 0.12 |
| TF superclass | Zinc-coordinating DNA-binding domains {2} (TFClass) |
| TF class | C2H2 zinc finger factors {2.3} (TFClass) |
| TF family | Three-zinc finger Kruppel-related {2.3.1} (TFClass) |
| TF subfamily | Kr-like {2.3.1.2} (TFClass) |
| TFClass ID | TFClass: 2.3.1.2.14 |
| HGNC | HGNC:23025 |
| MGI | MGI:3577024 |
| EntrezGene (human) | GeneID:136259 (SSTAR profile) |
| EntrezGene (mouse) | GeneID:619665 (SSTAR profile) |
| UniProt ID (human) | KLF14_HUMAN |
| UniProt ID (mouse) | KLF14_MOUSE |
| UniProt AC (human) | Q8TD94 (TFClass) |
| UniProt AC (mouse) | Q19A41 (TFClass) |
| GRECO-DB-TF | yes |
| ChIP-Seq | 1 human, 0 mouse |
| HT-SELEX | 3 |
| Methyl-HT-SELEX | 1 |
| PCM | KLF14.H12INVIVO.1.P.C.pcm |
| PWM | KLF14.H12INVIVO.1.P.C.pwm |
| PFM | KLF14.H12INVIVO.1.P.C.pfm |
| Alignment | KLF14.H12INVIVO.1.P.C.words.tsv |
| Threshold to P-value map | KLF14.H12INVIVO.1.P.C.thr |
| Motif in other formats | |
| JASPAR format | KLF14.H12INVIVO.1.P.C_jaspar_format.txt |
| MEME format | KLF14.H12INVIVO.1.P.C_meme_format.meme |
| Transfac format | KLF14.H12INVIVO.1.P.C_transfac_format.txt |
| Homer format | |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 161.0 | 147.0 | 512.0 | 177.0 |
| 02 | 219.0 | 164.0 | 572.0 | 42.0 |
| 03 | 393.0 | 137.0 | 353.0 | 114.0 |
| 04 | 352.0 | 77.0 | 380.0 | 188.0 |
| 05 | 266.0 | 20.0 | 676.0 | 35.0 |
| 06 | 211.0 | 16.0 | 454.0 | 316.0 |
| 07 | 218.0 | 18.0 | 717.0 | 44.0 |
| 08 | 57.0 | 17.0 | 804.0 | 119.0 |
| 09 | 48.0 | 24.0 | 902.0 | 23.0 |
| 10 | 174.0 | 543.0 | 1.0 | 279.0 |
| 11 | 34.0 | 19.0 | 924.0 | 20.0 |
| 12 | 74.0 | 11.0 | 578.0 | 334.0 |
| 13 | 146.0 | 24.0 | 759.0 | 68.0 |
| 14 | 214.0 | 62.0 | 571.0 | 150.0 |
| 15 | 144.0 | 520.0 | 242.0 | 91.0 |
| 16 | 173.0 | 341.0 | 177.0 | 306.0 |
| 17 | 184.0 | 165.0 | 527.0 | 121.0 |
| 18 | 172.0 | 150.0 | 450.0 | 225.0 |
| 19 | 213.0 | 141.0 | 586.0 | 57.0 |
| 20 | 236.0 | 121.0 | 430.0 | 210.0 |
| 21 | 130.0 | 139.0 | 588.0 | 140.0 |
| 22 | 231.0 | 106.0 | 460.0 | 200.0 |
| 23 | 144.0 | 124.0 | 630.0 | 99.0 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | 0.161 | 0.147 | 0.514 | 0.178 |
| 02 | 0.22 | 0.164 | 0.574 | 0.042 |
| 03 | 0.394 | 0.137 | 0.354 | 0.114 |
| 04 | 0.353 | 0.077 | 0.381 | 0.189 |
| 05 | 0.267 | 0.02 | 0.678 | 0.035 |
| 06 | 0.212 | 0.016 | 0.455 | 0.317 |
| 07 | 0.219 | 0.018 | 0.719 | 0.044 |
| 08 | 0.057 | 0.017 | 0.806 | 0.119 |
| 09 | 0.048 | 0.024 | 0.905 | 0.023 |
| 10 | 0.175 | 0.545 | 0.001 | 0.28 |
| 11 | 0.034 | 0.019 | 0.927 | 0.02 |
| 12 | 0.074 | 0.011 | 0.58 | 0.335 |
| 13 | 0.146 | 0.024 | 0.761 | 0.068 |
| 14 | 0.215 | 0.062 | 0.573 | 0.15 |
| 15 | 0.144 | 0.522 | 0.243 | 0.091 |
| 16 | 0.174 | 0.342 | 0.178 | 0.307 |
| 17 | 0.185 | 0.165 | 0.529 | 0.121 |
| 18 | 0.173 | 0.15 | 0.451 | 0.226 |
| 19 | 0.214 | 0.141 | 0.588 | 0.057 |
| 20 | 0.237 | 0.121 | 0.431 | 0.211 |
| 21 | 0.13 | 0.139 | 0.59 | 0.14 |
| 22 | 0.232 | 0.106 | 0.461 | 0.201 |
| 23 | 0.144 | 0.124 | 0.632 | 0.099 |
| A | C | G | T | |
|---|---|---|---|---|
| 01 | -0.433 | -0.523 | 0.716 | -0.34 |
| 02 | -0.128 | -0.415 | 0.827 | -1.747 |
| 03 | 0.453 | -0.593 | 0.346 | -0.774 |
| 04 | 0.343 | -1.159 | 0.419 | -0.28 |
| 05 | 0.065 | -2.447 | 0.993 | -1.922 |
| 06 | -0.165 | -2.65 | 0.597 | 0.236 |
| 07 | -0.133 | -2.543 | 1.052 | -1.703 |
| 08 | -1.452 | -2.595 | 1.166 | -0.732 |
| 09 | -1.619 | -2.278 | 1.281 | -2.317 |
| 10 | -0.356 | 0.775 | -4.522 | 0.112 |
| 11 | -1.949 | -2.494 | 1.305 | -2.447 |
| 12 | -1.198 | -2.982 | 0.837 | 0.291 |
| 13 | -0.53 | -2.278 | 1.109 | -1.281 |
| 14 | -0.151 | -1.371 | 0.825 | -0.503 |
| 15 | -0.544 | 0.732 | -0.029 | -0.996 |
| 16 | -0.362 | 0.312 | -0.34 | 0.204 |
| 17 | -0.301 | -0.409 | 0.745 | -0.715 |
| 18 | -0.368 | -0.503 | 0.588 | -0.102 |
| 19 | -0.156 | -0.564 | 0.851 | -1.452 |
| 20 | -0.054 | -0.715 | 0.542 | -0.17 |
| 21 | -0.645 | -0.579 | 0.854 | -0.571 |
| 22 | -0.075 | -0.846 | 0.61 | -0.218 |
| 23 | -0.544 | -0.691 | 0.923 | -0.913 |
| P-value | Threshold |
|---|---|
| 0.001 | 4.26976 |
| 0.0005 | 5.16606 |
| 0.0001 | 7.04456 |