MotifKLF14.H12INVIVO.0.PSM.A
Gene (human)KLF14
(GeneCards)
Gene synonyms (human)BTEB5
Gene (mouse)Klf14
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype0
Quality
A
Motif length14
ConsensusnddRKGGGCGTKdb
GC content66.78%
Information content (bits; total / per base)13.522 / 0.966
Data sourcesChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words8298

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.738 0.768 0.587 0.632 0.754 0.756 2.511 2.548 8.921 17.538

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.864 0.846 0.786 0.778 0.737 0.73
best 0.987 0.977 0.979 0.966 0.957 0.939
Methyl HT-SELEX, 1 experiments median 0.965 0.939 0.949 0.92 0.914 0.881
best 0.965 0.939 0.949 0.92 0.914 0.881
Non-Methyl HT-SELEX, 3 experiments median 0.763 0.753 0.623 0.636 0.559 0.578
best 0.987 0.977 0.979 0.966 0.957 0.939

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.62 0.057 0.243 0.167
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyThree-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamilyKr-like {2.3.1.2} (TFClass)
TFClass IDTFClass: 2.3.1.2.14
HGNCHGNC:23025
MGIMGI:3577024
EntrezGene (human)GeneID:136259
(SSTAR profile)
EntrezGene (mouse)GeneID:619665
(SSTAR profile)
UniProt ID (human)KLF14_HUMAN
UniProt ID (mouse)KLF14_MOUSE
UniProt AC (human)Q8TD94
(TFClass)
UniProt AC (mouse)Q19A41
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
012181.751310.752745.752059.75
022733.5988.52665.51910.5
033051.0692.03059.01496.0
041605.0237.05839.0617.0
05624.0106.04462.03106.0
06590.040.07559.0109.0
0721.026.08234.017.0
080.01.08295.02.0
0933.08185.04.076.0
101.00.08295.02.0
1175.076.0730.07417.0
12859.0129.05663.01647.0
131090.5640.53354.53212.5
141165.252740.251497.252895.25
PFM
ACGT
010.2630.1580.3310.248
020.3290.1190.3210.23
030.3680.0830.3690.18
040.1930.0290.7040.074
050.0750.0130.5380.374
060.0710.0050.9110.013
070.0030.0030.9920.002
080.00.01.00.0
090.0040.9860.00.009
100.00.01.00.0
110.0090.0090.0880.894
120.1040.0160.6820.198
130.1310.0770.4040.387
140.140.330.180.349
PWM
ACGT
010.05-0.4580.28-0.007
020.276-0.740.25-0.082
030.385-1.0960.388-0.327
04-0.256-2.1611.034-1.21
05-1.199-2.9540.7650.403
06-1.255-3.8951.292-2.927
07-4.492-4.2971.378-4.681
08-6.825-6.4581.385-6.19
09-4.0761.372-5.805-3.279
10-6.458-6.8251.385-6.19
11-3.291-3.279-1.0421.273
12-0.88-2.7611.004-0.23
13-0.642-1.1730.480.437
14-0.5760.278-0.3260.333
Standard thresholds
P-value Threshold
0.001 2.83816
0.0005 4.22986
0.0001 7.02266