MotifKLF14.H12INVITRO.1.P.C
Gene (human)KLF14
(GeneCards)
Gene synonyms (human)BTEB5
Gene (mouse)Klf14
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype1
Quality
C
Motif length23
ConsensusvdGdRGGYGKRRvnvbRdvdRdv
GC content67.61%
Information content (bits; total / per base)12.108 / 0.526
Data sourcesChIP-Seq
Aligned words998

ChIP-Seq benchmarking Num. of experiments (peaksets) auROC, median auROC, best auPRC, median auPRC, best pseudo-auROC, median pseudo-auROC, best pseudo-log-auROC, median pseudo-log-auROC, best Centrality, median Centrality, best
Human 1 (6) 0.684 0.7 0.499 0.519 0.804 0.819 3.03 3.074 1.509 5.854

HT-SELEX benchmarking auROC10 auPRC10 auROC25 auPRC25 auROC50 auPRC50
Overall, 4 experiments median 0.695 0.654 0.66 0.629 0.629 0.605
best 0.885 0.824 0.841 0.783 0.776 0.729
Methyl HT-SELEX, 1 experiments median 0.842 0.769 0.809 0.74 0.759 0.702
best 0.842 0.769 0.809 0.74 0.759 0.702
Non-Methyl HT-SELEX, 3 experiments median 0.547 0.539 0.512 0.517 0.499 0.508
best 0.885 0.824 0.841 0.783 0.776 0.729

rSNP benchmarking, SNP-SELEX auROC auPRC Pearson r Kendall tau
batch 2 0.53 0.01 0.363 0.1
TF superclassZinc-coordinating DNA-binding domains {2} (TFClass)
TF classC2H2 zinc finger factors {2.3} (TFClass)
TF familyThree-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamilyKr-like {2.3.1.2} (TFClass)
TFClass IDTFClass: 2.3.1.2.14
HGNCHGNC:23025
MGIMGI:3577024
EntrezGene (human)GeneID:136259
(SSTAR profile)
EntrezGene (mouse)GeneID:619665
(SSTAR profile)
UniProt ID (human)KLF14_HUMAN
UniProt ID (mouse)KLF14_MOUSE
UniProt AC (human)Q8TD94
(TFClass)
UniProt AC (mouse)Q19A41
(TFClass)
GRECO-DB-TF
yes
ChIP-Seq 1 human, 0 mouse
HT-SELEX 3
Methyl-HT-SELEX 1
PCM
ACGT
01312.0200.0398.088.0
02373.0106.0251.0268.0
03153.012.0791.042.0
04166.045.0480.0307.0
05206.041.0706.045.0
0683.011.0825.079.0
0764.043.0878.013.0
08211.0551.05.0231.0
0924.023.0937.014.0
1041.033.0614.0310.0
11185.040.0704.069.0
12239.044.0584.0131.0
13154.0528.0249.067.0
14173.0365.0170.0290.0
15219.0159.0494.0126.0
16133.0149.0519.0197.0
17209.0140.0590.059.0
18280.099.0418.0201.0
19172.0142.0589.095.0
20264.0100.0389.0245.0
21162.094.0659.083.0
22232.083.0503.0180.0
23168.0185.0573.072.0
PFM
ACGT
010.3130.20.3990.088
020.3740.1060.2520.269
030.1530.0120.7930.042
040.1660.0450.4810.308
050.2060.0410.7070.045
060.0830.0110.8270.079
070.0640.0430.880.013
080.2110.5520.0050.231
090.0240.0230.9390.014
100.0410.0330.6150.311
110.1850.040.7050.069
120.2390.0440.5850.131
130.1540.5290.2490.067
140.1730.3660.170.291
150.2190.1590.4950.126
160.1330.1490.520.197
170.2090.140.5910.059
180.2810.0990.4190.201
190.1720.1420.590.095
200.2650.10.390.245
210.1620.0940.660.083
220.2320.0830.5040.18
230.1680.1850.5740.072
PWM
ACGT
010.222-0.2190.464-1.03
020.4-0.8470.0060.071
03-0.485-2.9071.149-1.748
04-0.404-1.6820.6510.206
05-0.19-1.7721.036-1.682
06-1.087-2.9831.191-1.135
07-1.341-1.7261.253-2.837
08-0.1660.789-3.62-0.076
09-2.279-2.3181.318-2.771
10-1.772-1.9790.8960.216
11-0.297-1.7951.033-1.268
12-0.043-1.7040.846-0.638
13-0.4780.746-0.002-1.296
14-0.3630.378-0.380.149
15-0.129-0.4470.68-0.676
16-0.623-0.5110.729-0.234
17-0.176-0.5720.857-1.42
180.115-0.9140.513-0.214
19-0.369-0.5580.855-0.954
200.056-0.9040.442-0.018
21-0.428-0.9650.967-1.087
22-0.072-1.0870.698-0.324
23-0.392-0.2970.828-1.226
Standard thresholds
P-value Threshold
0.001 4.25211
0.0005 5.14496
0.0001 7.02231