KLF14.H12INVITRO.1.P.C motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF14.H12INVITRO.1.P.C
Gene (human)	KLF14 (GeneCards)
Gene synonyms (human)	BTEB5
Gene (mouse)	Klf14
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	1
Quality	C

Motif length	23
Consensus	vdGdRGGYGKRRvnvbRdvdRdv
GC content	67.61%
Information content (bits; total / per base)	12.108 / 0.526
Data sources	ChIP-Seq
Aligned words	998

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.684	0.7	0.499	0.519	0.804	0.819	3.03	3.074	1.509	5.854

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.695	0.654	0.66	0.629	0.629	0.605
Overall, 4 experiments	best	0.885	0.824	0.841	0.783	0.776	0.729
Methyl HT-SELEX, 1 experiments	median	0.842	0.769	0.809	0.74	0.759	0.702
Methyl HT-SELEX, 1 experiments	best	0.842	0.769	0.809	0.74	0.759	0.702
Non-Methyl HT-SELEX, 3 experiments	median	0.547	0.539	0.512	0.517	0.499	0.508
Non-Methyl HT-SELEX, 3 experiments	best	0.885	0.824	0.841	0.783	0.776	0.729

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.53	0.01	0.363	0.1

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.14
HGNC	HGNC:23025
MGI	MGI:3577024
EntrezGene (human)	GeneID:136259 (SSTAR profile)
EntrezGene (mouse)	GeneID:619665 (SSTAR profile)
UniProt ID (human)	KLF14_HUMAN
UniProt ID (mouse)	KLF14_MOUSE
UniProt AC (human)	Q8TD94 (TFClass)
UniProt AC (mouse)	Q19A41 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	KLF14.H12INVITRO.1.P.C.pcm
PWM	KLF14.H12INVITRO.1.P.C.pwm
PFM	KLF14.H12INVITRO.1.P.C.pfm
Alignment	KLF14.H12INVITRO.1.P.C.words.tsv
Threshold to P-value map	KLF14.H12INVITRO.1.P.C.thr
Motif in other formats
JASPAR format	KLF14.H12INVITRO.1.P.C_jaspar_format.txt
MEME format	KLF14.H12INVITRO.1.P.C_meme_format.meme
Transfac format	KLF14.H12INVITRO.1.P.C_transfac_format.txt
Homer format	KLF14.H12INVITRO.1.P.C_homer_format_0.001.txt KLF14.H12INVITRO.1.P.C_homer_format_0.0005.txt KLF14.H12INVITRO.1.P.C_homer_format_0.0001.txt

PCM

	A	C	G	T
01	312.0	200.0	398.0	88.0
02	373.0	106.0	251.0	268.0
03	153.0	12.0	791.0	42.0
04	166.0	45.0	480.0	307.0
05	206.0	41.0	706.0	45.0
06	83.0	11.0	825.0	79.0
07	64.0	43.0	878.0	13.0
08	211.0	551.0	5.0	231.0
09	24.0	23.0	937.0	14.0
10	41.0	33.0	614.0	310.0
11	185.0	40.0	704.0	69.0
12	239.0	44.0	584.0	131.0
13	154.0	528.0	249.0	67.0
14	173.0	365.0	170.0	290.0
15	219.0	159.0	494.0	126.0
16	133.0	149.0	519.0	197.0
17	209.0	140.0	590.0	59.0
18	280.0	99.0	418.0	201.0
19	172.0	142.0	589.0	95.0
20	264.0	100.0	389.0	245.0
21	162.0	94.0	659.0	83.0
22	232.0	83.0	503.0	180.0
23	168.0	185.0	573.0	72.0

PFM

	A	C	G	T
01	0.313	0.2	0.399	0.088
02	0.374	0.106	0.252	0.269
03	0.153	0.012	0.793	0.042
04	0.166	0.045	0.481	0.308
05	0.206	0.041	0.707	0.045
06	0.083	0.011	0.827	0.079
07	0.064	0.043	0.88	0.013
08	0.211	0.552	0.005	0.231
09	0.024	0.023	0.939	0.014
10	0.041	0.033	0.615	0.311
11	0.185	0.04	0.705	0.069
12	0.239	0.044	0.585	0.131
13	0.154	0.529	0.249	0.067
14	0.173	0.366	0.17	0.291
15	0.219	0.159	0.495	0.126
16	0.133	0.149	0.52	0.197
17	0.209	0.14	0.591	0.059
18	0.281	0.099	0.419	0.201
19	0.172	0.142	0.59	0.095
20	0.265	0.1	0.39	0.245
21	0.162	0.094	0.66	0.083
22	0.232	0.083	0.504	0.18
23	0.168	0.185	0.574	0.072

PWM

	A	C	G	T
01	0.222	-0.219	0.464	-1.03
02	0.4	-0.847	0.006	0.071
03	-0.485	-2.907	1.149	-1.748
04	-0.404	-1.682	0.651	0.206
05	-0.19	-1.772	1.036	-1.682
06	-1.087	-2.983	1.191	-1.135
07	-1.341	-1.726	1.253	-2.837
08	-0.166	0.789	-3.62	-0.076
09	-2.279	-2.318	1.318	-2.771
10	-1.772	-1.979	0.896	0.216
11	-0.297	-1.795	1.033	-1.268
12	-0.043	-1.704	0.846	-0.638
13	-0.478	0.746	-0.002	-1.296
14	-0.363	0.378	-0.38	0.149
15	-0.129	-0.447	0.68	-0.676
16	-0.623	-0.511	0.729	-0.234
17	-0.176	-0.572	0.857	-1.42
18	0.115	-0.914	0.513	-0.214
19	-0.369	-0.558	0.855	-0.954
20	0.056	-0.904	0.442	-0.018
21	-0.428	-0.965	0.967	-1.087
22	-0.072	-1.087	0.698	-0.324
23	-0.392	-0.297	0.828	-1.226

Standard thresholds

P-value	Threshold
0.001	4.25211
0.0005	5.14496
0.0001	7.02231