KLF14.H12INVITRO.0.PSM.A motif - HOmo sapiens COmprehensive MOdel COllection

Motif	KLF14.H12INVITRO.0.PSM.A
Gene (human)	KLF14 (GeneCards)
Gene synonyms (human)	BTEB5
Gene (mouse)	Klf14
Gene synonyms (mouse)
LOGO
LOGO (reverse complement)
Motif subtype	0
Quality	A

Motif length	14
Consensus	ddRKGGGCGTGKbn
GC content	70.35%
Information content (bits; total / per base)	14.81 / 1.058
Data sources	ChIP-Seq + HT-SELEX + Methyl-HT-SELEX
Aligned words	9938

ChIP-Seq benchmarking	Num. of experiments (peaksets)	auROC, median	auROC, best	auPRC, median	auPRC, best	pseudo-auROC, median	pseudo-auROC, best	pseudo-log-auROC, median	pseudo-log-auROC, best	Centrality, median	Centrality, best
Human	1 (6)	0.727	0.757	0.587	0.628	0.753	0.762	2.599	2.645	9.056	16.155

HT-SELEX benchmarking		auROC10	auPRC10	auROC25	auPRC25	auROC50	auPRC50
Overall, 4 experiments	median	0.873	0.854	0.795	0.788	0.748	0.744
Overall, 4 experiments	best	0.987	0.976	0.981	0.968	0.963	0.946
Methyl HT-SELEX, 1 experiments	median	0.97	0.946	0.961	0.934	0.937	0.907
Methyl HT-SELEX, 1 experiments	best	0.97	0.946	0.961	0.934	0.937	0.907
Non-Methyl HT-SELEX, 3 experiments	median	0.777	0.761	0.63	0.642	0.558	0.581
Non-Methyl HT-SELEX, 3 experiments	best	0.987	0.976	0.981	0.968	0.963	0.946

rSNP benchmarking, SNP-SELEX	auROC	auPRC	Pearson r	Kendall tau
batch 2	0.574	0.054	0.28	0.22

TF superclass	Zinc-coordinating DNA-binding domains {2} (TFClass)
TF class	C2H2 zinc finger factors {2.3} (TFClass)
TF family	Three-zinc finger Kruppel-related {2.3.1} (TFClass)
TF subfamily	Kr-like {2.3.1.2} (TFClass)
TFClass ID	TFClass: 2.3.1.2.14
HGNC	HGNC:23025
MGI	MGI:3577024
EntrezGene (human)	GeneID:136259 (SSTAR profile)
EntrezGene (mouse)	GeneID:619665 (SSTAR profile)
UniProt ID (human)	KLF14_HUMAN
UniProt ID (mouse)	KLF14_MOUSE
UniProt AC (human)	Q8TD94 (TFClass)
UniProt AC (mouse)	Q19A41 (TFClass)
GRECO-DB-TF	yes

ChIP-Seq	1 human, 0 mouse
HT-SELEX	3
Methyl-HT-SELEX	1

PCM	KLF14.H12INVITRO.0.PSM.A.pcm
PWM	KLF14.H12INVITRO.0.PSM.A.pwm
PFM	KLF14.H12INVITRO.0.PSM.A.pfm
Alignment	KLF14.H12INVITRO.0.PSM.A.words.tsv
Threshold to P-value map	KLF14.H12INVITRO.0.PSM.A.thr
Motif in other formats
JASPAR format	KLF14.H12INVITRO.0.PSM.A_jaspar_format.txt
MEME format	KLF14.H12INVITRO.0.PSM.A_meme_format.meme
Transfac format	KLF14.H12INVITRO.0.PSM.A_transfac_format.txt
Homer format	KLF14.H12INVITRO.0.PSM.A_homer_format_0.001.txt KLF14.H12INVITRO.0.PSM.A_homer_format_0.0005.txt KLF14.H12INVITRO.0.PSM.A_homer_format_0.0001.txt

PCM

	A	C	G	T
01	2469.75	1319.75	4168.75	1979.75
02	2835.75	1116.75	4047.75	1937.75
03	2246.0	210.0	6801.0	681.0
04	1124.0	27.0	4772.0	4015.0
05	1332.0	1.0	8596.0	9.0
06	0.0	0.0	9938.0	0.0
07	0.0	0.0	9938.0	0.0
08	100.0	9654.0	0.0	184.0
09	0.0	0.0	9936.0	2.0
10	31.0	39.0	191.0	9677.0
11	784.0	18.0	8929.0	207.0
12	1584.0	232.0	5498.0	2624.0
13	1127.5	5022.5	1551.5	2236.5
14	2045.0	2247.0	3625.0	2021.0

PFM

	A	C	G	T
01	0.249	0.133	0.419	0.199
02	0.285	0.112	0.407	0.195
03	0.226	0.021	0.684	0.069
04	0.113	0.003	0.48	0.404
05	0.134	0.0	0.865	0.001
06	0.0	0.0	1.0	0.0
07	0.0	0.0	1.0	0.0
08	0.01	0.971	0.0	0.019
09	0.0	0.0	1.0	0.0
10	0.003	0.004	0.019	0.974
11	0.079	0.002	0.898	0.021
12	0.159	0.023	0.553	0.264
13	0.113	0.505	0.156	0.225
14	0.206	0.226	0.365	0.203

PWM

	A	C	G	T
01	-0.006	-0.632	0.517	-0.227
02	0.132	-0.799	0.488	-0.248
03	-0.101	-2.461	1.006	-1.292
04	-0.792	-4.441	0.652	0.48
05	-0.623	-6.625	1.241	-5.394
06	-6.985	-6.985	1.386	-6.985
07	-6.985	-6.985	1.386	-6.985
08	-3.191	1.357	-6.985	-2.591
09	-6.985	-6.985	1.385	-6.36
10	-4.313	-4.098	-2.555	1.359
11	-1.151	-4.808	1.279	-2.475
12	-0.45	-2.362	0.794	0.055
13	-0.789	0.703	-0.47	-0.105
14	-0.194	-0.1	0.377	-0.206

Standard thresholds

P-value	Threshold
0.001	1.39236
0.0005	3.05266
0.0001	6.42056